Pertussis
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CLINICAL_TRIALS trial_result · 2026-08-17Clinical Trial Update: A Study on the Immune Response and Safety of a Combined Vaccine Against Diphtheria, Tetanus and Acellular Pertussis (dTpa) in Healthy Japanese Adolescents Aged 11 Years to <13 Years [Phase 3]
Phase 3 trial evaluating immune response and safety of a combined diphtheria-tetanus-acellular pertussis vaccine (dTpa) in healthy Japanese …
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: Safety and Immunogenicity Study of Tdap Vaccinations for Plasma Donors [Phase 2]
Phase 2 trial evaluating safety and immunogenicity of Tdap vaccinations in plasma donors; results completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-06-22Clinical Trial Results: Establishing a Controlled Human Infection Model of Bordetella Pertussis [Phase 1]
Phase 1 clinical trial results establishing a controlled human infection model for Bordetella pertussis.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Safety of Tetanus, Diphtheria, Acellular Pertussis With 5 Acellular Pertussis Components (Tdap5) Vaccination During Pregnancy
This clinical trial update reports on the safety of the Tdap5 vaccine administered during pregnancy; the study is active but not currently r…
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EMA approval · 2026-03-31EMA Authorised: Vaxelis (Diphtheria toxoid;tetanus toxoid;Bordetella pertussis antigens: pertussis toxoid, filamentous haemagglutinin, pertactin, fimbriae Types 2 and 3;hepatitis B surface antigen produced in yeast cells;poliovirus (inactivated): type 1 (Mahoney), type 2 (MEF-1), type 3 (Saukett) produced in Vero cells/ Haemophilus influenzae type b polysaccharide (polyribosylribitol phosphate) conjugated to meningococcal protein.) — MCM Vaccine B.V.
The EMA has authorised Vaxelis, a combination vaccine containing diphtheria and tetanus toxoids, pertussis antigens, hepatitis B surface ant…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) [Phase 1]
A Phase I clinical trial update for an absorbed acellular pertussis–diphtheria–tetanus vaccine intended for adults and adolescents; the stud…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Concurrent Versus Sequential Administration of Tdap and RSV Vaccines in Pregnancy [Phase 4]
Phase 4 clinical trial evaluating concurrent versus sequential administration of Tdap and an RSV vaccine in pregnant individuals.
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EMA approval · 2026-03-05EMA Authorised: VacPertagen (recombinant pertussis toxin;filamentous haemagglutinin) — BioNet Europe
The EMA authorised VacPertagen, a pertussis vaccine containing recombinant pertussis toxin and filamentous haemagglutinin, for protection ag…
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CLINICAL_TRIALS safety_alert · 2026-03-03Clinical Trial Update: Safety Monitoring of Boostagen® Vaccine in Thailand
A safety monitoring update for Boostagen Vaccine in Thailand indicates the study safety monitoring has been completed, with the vaccine bein…
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CLINICAL_TRIALS other · 2026-02-18Clinical Trial Update: Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine [Phase 1, Phase 2]
This entry notes a Phase I/II clinical trial evaluating a reduced-dose Diphtheria-Tetanus-Pertussis vaccine; the study is not yet recruiting…
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EMA approval · 2026-02-12EMA Authorised: Infanrix Hexa (Diphtheria toxoid;tetanus toxoid;Bordetella pertussis antigens (pertussis toxoid, filamentous haemagglutinin, pertactin);hepatitis B surface antigen;poliovirus (inactivated) (type-1 (Mahoney strain), type-2 (MEF-1 strain), type-3 (Saukett strain));Haemophilus influenzae type b polysaccharide) — GlaxoSmithKline Biologicals S.A.
The European Medicines Agency authorised Infanrix Hexa, a hexavalent vaccine that combines diphtheria, tetanus, pertussis, hepatitis B, poli…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Safety Monitoring of VacPertagen Vaccine in Thailand
Safety monitoring update for the VacPertagen vaccine trial in Thailand investigating pertussis, with the study reported as completed and ong…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Maternal Determinants of Infant Immunity to Pertussis [Phase 4]
A Phase 4 clinical trial evaluated maternal factors that influence infant immunity to pertussis. The study status is completed.
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine [Phase 1]
This is a Phase 1 clinical trial evaluating an adsorbed, acellular pertussis vaccine component combined with Hib and ACWY meningococcal comp…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: First Adult Safety Trial on Nasal Live Attenuated B. Pertussis Vaccine [Phase 1]
This document reports the completion of the first adult safety trial (Phase 1) of an intranasal live attenuated Bordetella pertussis vaccine…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Establishing a Controlled Human Infection Model of Pertactin-deficient Bordetella Pertussis [Phase 1]
Phase 1 clinical trial update on establishing a controlled human infection model using pertactin-deficient Bordetella pertussis to study per…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: CARE-ID: Dynamics of Respiratory Infections in Children and Transmission in Households and Schools
The CARE-ID trial is currently recruiting to study dynamics of respiratory infections in children and transmission in households and schools…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Immunogenicity and Safety of BPZE1 Intranasal Pertussis Vaccine in Healthy School-age Children [Phase 2]
Phase 2 trial assessing the immunogenicity and safety of the BPZE1 intranasal pertussis vaccine in healthy school-age children has completed…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Immunogenicity of a Combined Diphtheria-Tetanus-recombinant Acellular Pertussis (DTaP) Vaccine in Healthy Toddlers [Phase 2, Phase 3]
Immunogenicity results from Phase 2 and Phase 3 trials of a combined Diphtheria-Tetanus-recombinant Acellular Pertussis (DTaP) vaccine in he…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Study Evaluating the Safety of a Recombinant Acellular Pertussis Vaccine in Adults [Phase 3]
A Phase 3 clinical trial is evaluating the safety of a recombinant acellular pertussis vaccine in adults; the study is currently active but …
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Study Evaluating the Safety of a Recombinant Acellular Pertussis Vaccine in Pregnant Women
A clinical trial updating the safety assessment of a recombinant acellular pertussis vaccine in pregnant women; the study is currently activ…
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EMA approval · 2025-09-29EMA Authorised: Hexyon (filamentous haemagglutinin;Haemophilus influenzae type B polysaccharide (polyribosylribitol phosphate);hepatitis B surface antigen;pertussis toxoid;poliovirus (inactivated) type 1 (Mahoney strain) produced on Vero cells;poliovirus (inactivated) type 2 (MEF-1 strain) produced on Vero cells;poliovirus (inactivated) type 3 (Saukett strain) produced on Vero cells;tetanus protein;tetanus toxoid adsorbed on aluminium hydroxide, hydrated;Diphtheria toxoid) — Sanofi Winthrop Industrie
EMA authorised Hexyon, a hexavalent vaccine combining protection against hepatitis B, diphtheria, tetanus, pertussis, Haemophilus influenzae…
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EMA approval · 2025-09-29EMA Authorised: Hexacima (hepatitis B surface antigen;Diphtheria toxoid;Bordetella pertussis antigens Pertussis Toxoid Filamentous Haemagglutinin;poliovirus (inactivated) type 1 (Mahoney) type 2 (MEF-1) type 3 (Saukett);Haemophilus influenzae type b polysaccharide (Polyribosylribitol Phosphate) conjugated to Tetanus protein;tetanus toxoid) — Sanofi Winthrop Industrie
The European Medicines Agency authorised Hexacima, a hexavalent vaccine combining hepatitis B surface antigen, diphtheria toxoid, pertussis …
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand [Phase 3]
Phase 3 study evaluating the DTwP-HepB-Hib-IPV (SHAN6) vaccine administered with routine vaccines in healthy infants and toddlers in Thailan…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed [Phase 3]
Phase 3 trial update for Beijing Institute of Biological Products' Diphtheria, Tetanus and Acellular Pertussis vaccine adsorbed; the study i…