Persistent Pulmonary Hypertension of the Newborn
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Milrinone in Congenital Diaphragmatic Hernia [Phase 2]
A Phase 2 trial evaluating milrinone for congenital diaphragmatic hernia with persistent pulmonary hypertension of the newborn has completed…
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Melatonin Effects on the Left Ventricular Function in Neonates With Persistent Pulmonary Hypertension [NA]
This clinical trial update reports completion of a study evaluating the effects of melatonin on left ventricular function in neonates with p…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: The Effect Of Nebulizied Nitroglycerin As An Adjuvant Therapy For Persistent Pulmonary Hypertension Of Newborns [NA]
This completed clinical trial evaluated nebulized nitroglycerin as an adjuvant therapy for persistent pulmonary hypertension of the newborn,…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Vardenafil Vs Sildenafil for the Treatment of Pulmonary Hypertension of the Newborn [Phase 1, Phase 2]
This clinical trial update reports completed Phase 1 and Phase 2 studies comparing vardenafil to sildenafil for treating persistent pulmonar…
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CLINICAL_TRIALS trial_result · 2025-02-05Clinical Trial Update: Treatment of Persistent Pulmonary Hypertension in Neonates With Nebulized Magnesium Sulfate [Phase 2, Phase 3]
A trial update indicates completion of Phase 2 and Phase 3 studies testing nebulized magnesium sulfate for persistent pulmonary hypertension…
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: Nebulized Magnesium Sulfate and Sildenafil for Persistent Pulmonary Hypertension of Newborn [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating nebulized magnesium sulfate in combination with sildenafil for Persistent Pulmonary Hypertension of th…
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CLINICAL_TRIALS trial_result · 2024-08-26Clinical Trial Update: Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in Children [NA]
Clinical trial update reporting on the efficacy of combining milrinone with sildenafil for persistent pulmonary hypertension of the newborn;…
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CLINICAL_TRIALS trial_result · 2024-03-05Clinical Trial Update: Remodulin as Add-on Therapy for the Treatment of Persistent Pulmonary Hypertension of the Newborn [Phase 2]
Phase 2 trial of Remodulin as add-on therapy for persistent pulmonary hypertension of the newborn has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2022-05-20Clinical Trial Update: Oral Sildenafil in Persistent Pulmonary Hypertension Secondary to Meconium Aspiration Syndrome in Newborns [Phase 4]
Phase 4 trial update evaluating oral sildenafil for persistent pulmonary hypertension in newborns with meconium aspiration syndrome has comp…
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CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: Nebulized MgSO4 in Persistent Pulmonary Hypertension of Newborn [Phase 1, Phase 2]
Phase 1/2 trial evaluating nebulized magnesium sulfate for persistent pulmonary hypertension of the newborn has completed.
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CLINICAL_TRIALS trial_result · 2020-03-25Clinical Trial Update: A Study To Evaluate Safety And Efficacy Of IV Sildenafil In The Treatment Of Neonates With Persistent Pulmonary Hypertension Of The Newborn [Phase 3]
Phase 3 trial evaluating safety and efficacy of intravenous sildenafil in neonates with persistent pulmonary hypertension; study completed w…
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: Markers of Inflammation and Lung Recovery in ECMO Patients for PPHN
Completed clinical trial studying inflammatory markers and lung recovery in ECMO-treated newborns with persistent pulmonary hypertension.
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Study of Sildenafil to Treat Newborns With Persistent Pulmonary Hypertension [Phase 2]
A Phase 2 study evaluating sildenafil for newborns with persistent pulmonary hypertension was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: Pharmacokinetics of Sildenafil in Premature Infants [Phase 1]
Phase 1 pharmacokinetic study of sildenafil in premature infants with persistent pulmonary hypertension of the newborn; the trial has comple…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: Plethismographic Perfusion Index in Neonates
Clinical trial update on Plethismographic Perfusion Index in neonates, involving patent ductus arteriosus and persistent pulmonary hypertens…
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CLINICAL_TRIALS trial_result · 2016-07-12Clinical Trial Update: Pharmacokinetic Study of Milrinone in Babies With Persistent Pulmonary Hypertension of the Newborn [NA]
This clinical trial update reports on a pharmacokinetic study of milrinone in newborns with persistent pulmonary hypertension of the newborn…
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CLINICAL_TRIALS trial_result · 2016-07-11Clinical Trial Update: N-Terminal Pro-brain Natriuretic Peptide Hormone and Persistent Pulmonary Hypertension
A clinical trial investigating N-terminal pro-brain natriuretic peptide (NT-proBNP) in persistent pulmonary hypertension of the newborn has …
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CLINICAL_TRIALS trial_result · 2015-03-23Clinical Trial Update: Persistent Pulmonary Hypertension of the Newborn [Phase 3]
A Phase 3 clinical trial for Persistent Pulmonary Hypertension of the Newborn was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2014-06-02Clinical Trial Update: Inhaled Iloprost for the Treatment of Persistent Pulmonary Hypertension in the Term and Near Term Infants. [Phase 4]
Phase 4 clinical trial evaluating inhaled iloprost for persistent pulmonary hypertension in term and near-term infants has been terminated.
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: NO Need to Ventilate: A Trial of Non-invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn [NA]
A completed clinical trial evaluating inhaled nitric oxide as non-invasive therapy for persistent pulmonary hypertension of the newborn.
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN) [Phase 2]
A Phase 2 trial assessing sildenafil for safety and efficacy in newborns with persistent pulmonary hypertension (PPHN) has been terminated w…
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CLINICAL_TRIALS trial_result · 2012-09-25Clinical Trial Update: Sildenofil in Persistent Pulmonary Hypertension in Newborns [Phase 3]
A Phase 3 clinical trial evaluating sildenafil for persistent pulmonary hypertension of the newborn is ongoing, sponsored by Hamad Medical C…
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CLINICAL_TRIALS trial_result · 2008-08-12Clinical Trial Update: Inhaled Nitric Oxide by Oxygen Hood in Neonates [Phase 4]
Phase 4 clinical trial evaluating inhaled nitric oxide delivered by an oxygen hood in neonates with respiratory failure, including persisten…