Periprosthetic Joint Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA) [Phase 1]
A Phase 1 clinical trial, sponsored by Peptilogics, evaluating a DAIR (debridement, antibiotics, and implant retention) approach for peripro…
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CLINICAL_TRIALS other · 2025-04-28Clinical Trial Update: One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection [NA]
Clinical trial update indicates a study comparing one-stage versus two-stage strategies for periprosthetic hip and knee infection is current…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Antibiotic Elution After Two-stage Knee Revision
A completed clinical trial from University Hospital Bonn evaluating antibiotic elution after a two-stage knee revision for periprosthetic jo…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a bacteriophage therapy for chronic Enterococcus faecium periprosthetic joint infection; recruitmen…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Single-stage Surgery With Antibiotic-loaded Hydrogel Coated Implants Versus Two Stage Surgery for Secondary Prevention of Complex Chronic Periprosthetic Hip Joint Infection [NA]
A clinical trial comparing single-stage surgery with antibiotic-loaded hydrogel-coated implants to two-stage surgery for secondary preventio…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Efficacy of New Silver-coated Prosthesis in Reducing the Incidence of Periprosthetic Infections
A clinical trial is evaluating whether a silver-coated prosthesis can reduce periprosthetic infections in hip arthroplasty. The study is cur…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Use of Phage Therapy for Treatment of a Periprosthetic Joint Infection [Phase 1]
Phase 1 study evaluating bacteriophage therapy for periprosthetic joint infection; currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: Results of Silver-coated Resection Prostheses in the Treatment of Periprosthetic Knee Infections with Bone Deficiency
Clinical trial results evaluating silver-coated resection knee prostheses for treatment of periprosthetic knee infections with bone deficien…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Molecular Biology in the Identification of Pathogens at Reimplantation in the Two-Stage Treatment of Periprosthetic Infections
This clinical trial update describes a study using molecular biology to identify pathogens at the reimplantation stage of the two-stage trea…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Bacteriophage Clinical Trial for Periprosthetic Joint Infection of Multidrug Resistant Pseudomonas Aeruginosa
An update on an ongoing clinical trial evaluating bacteriophage therapy for periprosthetic joint infection caused by multidrug-resistant Pse…
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CLINICAL_TRIALS trial_result · 2025-01-20Clinical Trial Update: Analysis of Risk Factors for Recurrence of Periprosthetic Infection in Megaprostheses Implanted for Sarcoma of Bone
Completed clinical trial analyzing risk factors for recurrence of periprosthetic joint infection in megaprostheses implanted for bone sarcom…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities [NA]
A multicenter clinical trial is recruiting to evaluate an antibiotic-eluting graft intended to promote bone growth in or near infected bone …
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Outcome After Revisions of Infected Knee Arthroplasties
Clinical trial update describing outcomes after revisions for periprosthetic joint infection of the knee.
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: One-stage Versus Two-stage Revision of the Infected Knee Arthroplasty [NA]
This document reports an ongoing clinical trial comparing one-stage versus two-stage revision surgery for infected knee arthroplasty; the st…
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Optimizing Infection Prophylaxis Prior to Shoulder Surgery [NA]
Clinical trial update on optimizing infection prophylaxis before shoulder arthroplasty to prevent periprosthetic joint infection.
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CLINICAL_TRIALS research · 2024-10-30Clinical Trial Update: Paper-based Electrochemical Point-of-care Device in Diagnostic of Orthopedic Infections
A clinical trial is investigating a paper-based electrochemical point-of-care device for diagnosing orthopedic infections, including peripro…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Early Discrimination of Periprosthetic Hip Infections Using Neural Networks (SEPTIC-ANNR)
The clinical trial SEPTIC-ANNR evaluated neural networks for early discrimination of periprosthetic hip infections; the study status is comp…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Infection Prophylaxis in Total Joint Replacement [Phase 3]
A Phase 3 clinical trial investigating infection prophylaxis in total joint replacement is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Efficacy of Local Antibiotic Injection Via a Catheter for Treating Acute Periprosthetic Infections After Knee DAIR Surgery [NA]
A randomized controlled trial to test local antibiotic catheter injections for treating acute knee periprosthetic joint infection after DAIR…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Prospective Cohort Study of Synovial Biomarkers in the Diagnosis and Prediction of Periprosthetic Joint Infection
This is a protocol for a prospective cohort study evaluating synovial biomarkers to aid diagnosis and prediction of periprosthetic joint inf…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Diagnostic Accuracy of Synovial Biopsy for Implant-Related Shoulder Infections [NA]
An update on a study evaluating the diagnostic accuracy of synovial biopsy for implant-related shoulder infections in total shoulder arthrop…
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CLINICAL_TRIALS trial_result · 2022-06-16Clinical Trial Update: Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip [Phase 4]
Phase 4 clinical trial assessing periarticular penetration of cefazolin and clindamycin in second-stage revision hip arthroplasty for bone a…
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CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: Prophylaxis of Periprosthetic Joint Infections With Calcium Sulfate Beads in Patients With Non-modifiable Risk Factors. [Phase 4]
Phase 4 clinical trial evaluating calcium sulfate beads for prophylaxis of periprosthetic joint infections in patients with non-modifiable r…
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CLINICAL_TRIALS research · 2018-06-21Clinical Trial Update: Comparative Study With Different Tracers (18F-FDG and 68Gallium Citrate) in the Diagnosis of Periprosthetic Joint Infection [NA]
This clinical trial compares two PET tracers, 18F-FDG and 68Ga-citrate, for diagnosing periprosthetic joint infection.
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CLINICAL_TRIALS research · 2018-04-19Clinical Trial Update: Fructosamine as a Predictor of Surgical Outcomes in Total Joint Arthroplasty A Prospective Multi-center Study
A prospective multi-center study evaluating whether fructosamine levels can predict surgical outcomes after total joint arthroplasty, includ…