Periprosthetic Joint Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Study to Evaluate the REMEDY SPECTRUM IM Spacer Nail in the Treatment of Ankle-Related Infections [Phase 2]
A Phase 2 clinical trial evaluating the REMEDY SPECTRUM IM Spacer Nail for treating ankle-related periprosthetic joint infection is currentl…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Joint Endoprostheses Can Succesfully Treat Disabling Osteoarthritis. However, Infection is an Important Cause of Failure. Adequate Diagnostics Remains Challenging. Combining Advanced Imaging With Next-generation Sequencing of Samples Obtained Endoscopically Should Aid in Mapping and Characterizing. [NA]
A clinical trial is evaluating whether advanced imaging combined with next-generation sequencing of endoscopically obtained samples can map …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection [NA]
A clinical trial evaluating real-component versus all-cement articulating spacers for periprosthetic knee infection; the study is currently …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Genetic Susceptibility to Periprosthetic Joint Infections
A clinical trial update shows enrollment by invitation for a study investigating genetic susceptibility to periprosthetic joint infections i…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Assessment of Functional Outcomes of Custom-made Articulating Spacers in Two Stage Arthroplasty for Treatment of Infected Hip Joint [NA]
Clinical trial completed evaluating functional outcomes of custom-made articulating spacers in two-stage hip arthroplasty for the treatment …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI Participants [Phase 1, Phase 2]
A Phase 1/2 study evaluating the safety, pharmacokinetics and preliminary efficacy of TNP-2092 administered via intra-articular injection in…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Evaluation of Outcomes of the Triathlon Hinge Knee (THK) System
An ongoing clinical trial sponsored by The Cleveland Clinic is recruiting to evaluate outcomes of the Triathlon Hinge Knee System for knee j…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Incidence and Microbial Profiles of Periprosthetic Joint Infection After Total Knee Arthroplasty in Obese vs Non-Obese Patients
This completed trial compares infection rates and the bacteria involved in periprosthetic joint infections following total knee arthroplasty…
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CLINICAL_TRIALS withdrawal · 2026-02-10Clinical Trial Update: Proper Duration of Suppressive Antibiotic Therapy After Debridement, Antibiotics, and Implant Retention [NA]
This clinical trial update notes the withdrawal of a study examining the proper duration of suppressive antibiotic therapy after debridement…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Preop Biomarkers as Outcome Predictors in 2 Stage Revision Surgery for PJI
This clinical trial update describes a study evaluating preoperative biomarkers as predictors of outcomes in a two-stage revision surgery fo…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Clindamycin as Antimicrobial Treatment for Streptococcus Spp. PeRiprosthetic Infection
The document reports an ongoing clinical trial evaluating clindamycin as antimicrobial therapy for Streptococcus spp. periprosthetic infecti…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: IP-coated Revision Hip Implants [NA]
Aesculap AG is conducting a clinical trial evaluating IP-coated revision hip implants for prevention of peri-prosthetic joint infection, and…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Rifampin-combined Antibiotic Therapy for Staphylococcal PJI [NA]
This clinical trial update notes a study currently recruiting to evaluate rifampin-containing antibiotic therapy for staphylococcal peripros…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: One-stage Exchange in Candida Periprosthetic Infection a Suitable Way to go
A clinical trial at University Hospital Strasbourg is evaluating a one-stage exchange procedure for Candida periprosthetic infection and is …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Hip Infection: a Microdialysis Study
A microdialysis study is analyzing pharmacological aspects related to infection-free survival after surgical treatment of a periprosthetic j…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Knee Infection: a Microdialysis Study
Clinical trial update describing a microdialysis study evaluating pharmacological factors related to infection-free survival after surgical …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression [NA]
A Mayo Clinic clinical trial evaluating single versus planned double debridement with antibiotics and implant retention, followed by chronic…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Reinfection and Re-revision Rates of Periprosthetic Knee Infection Under Four Different Surgical Strategies
A completed clinical trial comparing four surgical strategies for managing periprosthetic knee infection after total knee arthroplasty, eval…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: The Use of CCK vs PS in Revision TKAs [Phase 4]
Phase 4 clinical trial evaluating Constrained Condylar Knee (CCK) versus Posterior-Stabilized (PS) implants in revision total knee arthropla…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Infection Consortium Study#1
A clinical trial related to periprosthetic joint infection sponsored by Zimmer Biomet has completed.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Intra-articular Vancomycin Powder in Knee and Hip Arthroplasty [NA]
Clinical trial investigating intra-articular vancomycin powder to prevent infection after knee and hip replacement; status is active but not…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Evaluation of Conventional Antibiotic Prophylaxis During a Change of Hip or Knee Infected at a Time
A completed clinical trial evaluated conventional antibiotic prophylaxis during revision surgery for infection in hip or knee prostheses.
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: Exploring Novel Diagnostic Tools for Periprosthetic Joint Infection
A completed clinical trial is evaluating novel diagnostic tools for detecting prosthesis-related infections in hip and knee arthroplasty.
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: A Diagnostic Test Accuracy Study Comparing Biopsy to Aspiration in Shoulder and Elbow Arthroplasty Revision Surgery (BASE Study)
A clinical trial update for the BASE Study evaluating diagnostic accuracy of biopsy versus aspiration in revision shoulder and elbow arthrop…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Evaluation of Emerging New Treatments for Infection Prevention in Total Joint Replacement [Phase 3]
Phase 3 study evaluating emerging treatments to prevent infection in total joint replacement has completed.