Periprosthetic Joint Infection
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Study to Evaluate the REMEDY SPECTRUM IM Spacer Nail in the Treatment of Ankle-Related Infections [Phase 2]
A Phase 2 clinical trial evaluating the REMEDY SPECTRUM IM Spacer Nail for treating ankle-related periprosthetic joint infection is currentl…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Joint Endoprostheses Can Succesfully Treat Disabling Osteoarthritis. However, Infection is an Important Cause of Failure. Adequate Diagnostics Remains Challenging. Combining Advanced Imaging With Next-generation Sequencing of Samples Obtained Endoscopically Should Aid in Mapping and Characterizing. [NA]
A clinical trial is evaluating whether advanced imaging combined with next-generation sequencing of endoscopically obtained samples can map …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Real-component vs All-cement Articulating Spacers for Periprosthetic Knee Infection [NA]
A clinical trial evaluating real-component versus all-cement articulating spacers for periprosthetic knee infection; the study is currently …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Genetic Susceptibility to Periprosthetic Joint Infections
A clinical trial update shows enrollment by invitation for a study investigating genetic susceptibility to periprosthetic joint infections i…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI Participants [Phase 1, Phase 2]
A Phase 1/2 study evaluating the safety, pharmacokinetics and preliminary efficacy of TNP-2092 administered via intra-articular injection in…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Evaluation of Outcomes of the Triathlon Hinge Knee (THK) System
An ongoing clinical trial sponsored by The Cleveland Clinic is recruiting to evaluate outcomes of the Triathlon Hinge Knee System for knee j…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Preop Biomarkers as Outcome Predictors in 2 Stage Revision Surgery for PJI
This clinical trial update describes a study evaluating preoperative biomarkers as predictors of outcomes in a two-stage revision surgery fo…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Clindamycin as Antimicrobial Treatment for Streptococcus Spp. PeRiprosthetic Infection
The document reports an ongoing clinical trial evaluating clindamycin as antimicrobial therapy for Streptococcus spp. periprosthetic infecti…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: IP-coated Revision Hip Implants [NA]
Aesculap AG is conducting a clinical trial evaluating IP-coated revision hip implants for prevention of peri-prosthetic joint infection, and…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Rifampin-combined Antibiotic Therapy for Staphylococcal PJI [NA]
This clinical trial update notes a study currently recruiting to evaluate rifampin-containing antibiotic therapy for staphylococcal peripros…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: One-stage Exchange in Candida Periprosthetic Infection a Suitable Way to go
A clinical trial at University Hospital Strasbourg is evaluating a one-stage exchange procedure for Candida periprosthetic infection and is …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Hip Infection: a Microdialysis Study
A microdialysis study is analyzing pharmacological aspects related to infection-free survival after surgical treatment of a periprosthetic j…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Analysis of Pharmacological Aspects Regarding Infection Free Survival After Surgical Treatment of a Periprosthetic Knee Infection: a Microdialysis Study
Clinical trial update describing a microdialysis study evaluating pharmacological factors related to infection-free survival after surgical …
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Treatment of Acute Periprosthetic Joint Infection Comparing Single and Planned Double-Debridement Antibiotics and Implant Retention Followed by Chronic Antibiotic Suppression [NA]
A Mayo Clinic clinical trial evaluating single versus planned double debridement with antibiotics and implant retention, followed by chronic…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: The Use of CCK vs PS in Revision TKAs [Phase 4]
Phase 4 clinical trial evaluating Constrained Condylar Knee (CCK) versus Posterior-Stabilized (PS) implants in revision total knee arthropla…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Intra-articular Vancomycin Powder in Knee and Hip Arthroplasty [NA]
Clinical trial investigating intra-articular vancomycin powder to prevent infection after knee and hip replacement; status is active but not…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: A Diagnostic Test Accuracy Study Comparing Biopsy to Aspiration in Shoulder and Elbow Arthroplasty Revision Surgery (BASE Study)
A clinical trial update for the BASE Study evaluating diagnostic accuracy of biopsy versus aspiration in revision shoulder and elbow arthrop…
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Phage Therapy for the Treatment of a Chronic Enterococcus Faecium Periprosthetic Joint Infection [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a bacteriophage therapy for chronic Enterococcus faecium periprosthetic joint infection; recruitmen…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Single-stage Surgery With Antibiotic-loaded Hydrogel Coated Implants Versus Two Stage Surgery for Secondary Prevention of Complex Chronic Periprosthetic Hip Joint Infection [NA]
A clinical trial comparing single-stage surgery with antibiotic-loaded hydrogel-coated implants to two-stage surgery for secondary preventio…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Efficacy of New Silver-coated Prosthesis in Reducing the Incidence of Periprosthetic Infections
A clinical trial is evaluating whether a silver-coated prosthesis can reduce periprosthetic infections in hip arthroplasty. The study is cur…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Use of Phage Therapy for Treatment of a Periprosthetic Joint Infection [Phase 1]
Phase 1 study evaluating bacteriophage therapy for periprosthetic joint infection; currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Molecular Biology in the Identification of Pathogens at Reimplantation in the Two-Stage Treatment of Periprosthetic Infections
This clinical trial update describes a study using molecular biology to identify pathogens at the reimplantation stage of the two-stage trea…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Bacteriophage Clinical Trial for Periprosthetic Joint Infection of Multidrug Resistant Pseudomonas Aeruginosa
An update on an ongoing clinical trial evaluating bacteriophage therapy for periprosthetic joint infection caused by multidrug-resistant Pse…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities [NA]
A multicenter clinical trial is recruiting to evaluate an antibiotic-eluting graft intended to promote bone growth in or near infected bone …
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: One-stage Versus Two-stage Revision of the Infected Knee Arthroplasty [NA]
This document reports an ongoing clinical trial comparing one-stage versus two-stage revision surgery for infected knee arthroplasty; the st…