Otoferlin-related Deafness

• CLINICAL_TRIALS trial_result · 2026-02-23
  Clinical Trial Update: A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants With Hearing Loss Due to Otoferlin Mutations [Phase 1, Phase 2]

  Regeneron's DB-OTO, an AAV-based gene therapy, is being evaluated in Phase 1/2 for congenital hearing loss due to biallelic OTOF mutations a…

• CLINICAL_TRIALS research · 2025-09-04
  Clinical Trial Update: A Comparative Analysis of Speech Perception Between Cochlear Implant Patients and DFNB9 Patients Receiving Gene Therapy

  A trial update describing ongoing recruitment for a comparative study of speech perception in cochlear implant users vs. DFNB9 patients rece…

• CLINICAL_TRIALS trial_result · 2025-07-25
  Clinical Trial Update: A Study of EH002 Gene Therapy for Otoferlin Gene Mutation-mediated Hearing Loss [NA]

  Clinical trial update shows EH002 gene therapy aimed at otoferlin gene mutation–mediated congenital hearing loss is actively recruiting; no …