Oral Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers [Phase 2, Phase 3]
This clinical trial update covers a study evaluating the safety and efficacy of PRV111, PRV211, and PRV131 in patients with oral squamous ce…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Neoadjuvant Becotatug Vedotin Plus Pucotenlimab in Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma (OSCC) [Phase 2]
Phase 2 neoadjuvant trial evaluating Becotatug Vedotin plus Pucotenlimab in locally advanced oral and oropharyngeal squamous cell carcinoma;…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas [Phase 1]
Phase 1 study evaluating safety, efficacy, and pharmacokinetics of EVOLVE104 in patients with advanced urothelial cancer and squamous cell c…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Evaluation of the Efficacy and Safety of Nivolumab Neoadjuvant Treatment of Patients With Locally Advanced Oral Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating nivolumab as neoadjuvant therapy for locally advanced oral squamous cell carcinoma; currently not recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions [Phase 2]
This Phase 2 clinical trial update from the University of Massachusetts examines low-cost screening and image-guided photodynamic therapy fo…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology
This ongoing preliminary study evaluates in vivo imaging of oral cancers using reflectance confocal microscopy and compares intra-oral imagi…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Impact of Postoperative Radiotherapy Versus PD-1 Inhibitor Maintenance on Survival in Resectable Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma
A clinical trial evaluating whether postoperative radiotherapy or PD-1 inhibitor maintenance improves survival in patients with resectable l…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer [Phase 2]
An ongoing Phase 2 clinical trial is evaluating how antibiotics affect intratumoral bacteria in surgical patients with oral squamous cell ca…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: "Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON) [NA]
This document is a clinical trial listing for an ultra-high-frequency intraoral ultrasonography device to image the tongue in patients with …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Evaluating Treatment Strategies for p53 Mutant Oral Cancer and Oral Cancer Precursors [NA]
A University of British Columbia study is evaluating treatment strategies for p53-mutant oral cancer and its precursors, with no recruitment…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Dye for the Detection of Cancer of the Tongue and Mouth [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating a fluorescent dye for detecting cancers of the tongue and mouth in oral squamous cell carcinoma.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Surgery With or Without Neoadjuvant Treatment of SBRT Plus Chemoimmunotherapy in Resectable Locally Advanced Oral and HPV-unrelated Oropharyngeal Squamous Cell Carcinoma [Phase 3]
A Phase 3 trial evaluating whether adding neoadjuvant SBRT plus chemoimmunotherapy before surgery improves outcomes in resectable locally ad…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx
A clinical trial is evaluating dual-energy CT versus MRI for staging or evaluating squamous cell carcinomas of the oral cavity and oropharyn…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Effectiveness of Hydrogen Water Intervention on Acute Oral Inflammation, Oral Microbiota, and Pain Following Free Flap Reconstruction in Patients With Oral Cancer [NA]
A clinical trial registry entry describing a study of hydrogen-rich water to reduce acute oral inflammation, alter the oral microbiota, and …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Enhancing Oral Cancer Awareness [NA]
A Virginia Commonwealth University-sponsored clinical trial aims to enhance oral cancer awareness using a chatbot for patient education and …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Tirellizumab Combined With TP Neoadjuvant Therapy in the Treatment of Early Oral Squamous Cell Carcinoma （HNC-SYSU-005） [Phase 2]
Phase 2 clinical trial update on Tirellizumab in combination with TP neoadjuvant therapy for early oral squamous cell carcinoma, currently a…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain [NA]
This clinical trial is recruiting to define how TRPV4 in Schwann cells may contribute to pain in oral squamous cell carcinoma.
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Prospective Cohort Study on Oral Microbiome Changes in Patients With Locally Advanced Oral Squamous Cell Carcinoma Following Neoadjuvant Chemoimmunotherapy
Prospective cohort study assessing changes in the oral microbiome of patients with locally advanced oral squamous cell carcinoma after neoad…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis
A registry is being established to collect data on patients undergoing segmental mandibular defect reconstruction after oral squamous cell c…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Adebrelimab Combined With Carboplatin and Albumin-bound Taxanol in the Treatment of Resectable Locally Advanced Oral Squamous Cell Carcinoma Cardiac, Randomized, Phase II Exploratory Study [Phase 2]
Phase II exploratory randomized neoadjuvant trial evaluating adebrelimab in combination with carboplatin and nab-paclitaxel for resectable l…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: A Bidirectional Observational Clinical Study of NAIC in the Treatment of Tumor Regression Patterns in LA-OSCC and LA-OPSCC
Observational bidirectional study of NAIC to examine tumor regression patterns in locally advanced oral squamous cell carcinoma and locally …
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Primary Tumor Depth of Invasion and Lymph Node Management in Oral Squamous Cell Carcinoma
A clinical trial update describes a study sponsored by Al-Azhar University examining how primary tumor depth of invasion and lymph node mana…
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Neoadjuvant and Adjuvant Sintilimab Plus Cetuximab in Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating neoadjuvant and adjuvant sintilimab plus cetuximab in resectable locally advanced oral and oropharyngeal s…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative [NA]
A clinical trial evaluating sentinel lymph node biopsy versus limited elective neck dissection in early oral cavity cancers with clinically …
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Neoadjuvant Low-Dose Radiotherapy Combined With Adebrelimab and Single-Agent Albumin-Bound Paclitaxel Chemotherapy for Early-Stage Oral Squamous Cell Carcinoma: A Prospective, Single-Arm Clinical Trial [Phase 2]
A Phase 2 single-arm trial is evaluating neoadjuvant low-dose radiotherapy in combination with adebrelimab and albumin-bound paclitaxel for …