Oral Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-01Clinical Trial Results: Laser Mucite ORL : Effectiveness of Laser Therapy for Mucositis Induced by a Radio-chemotherapy in Head and Neck Cancer [NA]
A completed clinical trial evaluating the effectiveness of laser therapy for mucositis induced by radio-chemotherapy in head and neck cancer…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers [Phase 2, Phase 3]
This clinical trial update covers a study evaluating the safety and efficacy of PRV111, PRV211, and PRV131 in patients with oral squamous ce…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Neoadjuvant Becotatug Vedotin Plus Pucotenlimab in Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma (OSCC) [Phase 2]
Phase 2 neoadjuvant trial evaluating Becotatug Vedotin plus Pucotenlimab in locally advanced oral and oropharyngeal squamous cell carcinoma;…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas [Phase 1]
Phase 1 study evaluating safety, efficacy, and pharmacokinetics of EVOLVE104 in patients with advanced urothelial cancer and squamous cell c…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Evaluation of the Efficacy and Safety of Nivolumab Neoadjuvant Treatment of Patients With Locally Advanced Oral Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating nivolumab as neoadjuvant therapy for locally advanced oral squamous cell carcinoma; currently not recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions [Phase 2]
This Phase 2 clinical trial update from the University of Massachusetts examines low-cost screening and image-guided photodynamic therapy fo…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology
This ongoing preliminary study evaluates in vivo imaging of oral cancers using reflectance confocal microscopy and compares intra-oral imagi…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Impact of Postoperative Radiotherapy Versus PD-1 Inhibitor Maintenance on Survival in Resectable Locally Advanced Oral and Oropharyngeal Squamous Cell Carcinoma
A clinical trial evaluating whether postoperative radiotherapy or PD-1 inhibitor maintenance improves survival in patients with resectable l…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer [Phase 2]
An ongoing Phase 2 clinical trial is evaluating how antibiotics affect intratumoral bacteria in surgical patients with oral squamous cell ca…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: "Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON) [NA]
This document is a clinical trial listing for an ultra-high-frequency intraoral ultrasonography device to image the tongue in patients with …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Evaluating Treatment Strategies for p53 Mutant Oral Cancer and Oral Cancer Precursors [NA]
A University of British Columbia study is evaluating treatment strategies for p53-mutant oral cancer and its precursors, with no recruitment…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Dye for the Detection of Cancer of the Tongue and Mouth [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating a fluorescent dye for detecting cancers of the tongue and mouth in oral squamous cell carcinoma.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Surgery With or Without Neoadjuvant Treatment of SBRT Plus Chemoimmunotherapy in Resectable Locally Advanced Oral and HPV-unrelated Oropharyngeal Squamous Cell Carcinoma [Phase 3]
A Phase 3 trial evaluating whether adding neoadjuvant SBRT plus chemoimmunotherapy before surgery improves outcomes in resectable locally ad…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: A Study of Vobramitamab Duocarmazine in Participants With Metastatic Castration Resistant Prostate Cancer and Other Solid Tumors [Phase 2]
A Phase 2 study evaluating vobramitamab duocarmazine in metastatic castration-resistant prostate cancer and other solid tumors was terminate…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma [Phase 3]
The document reports a Phase 3 trial evaluating Sintilimab plus chemotherapy as neoadjuvant and adjuvant therapy for locally advanced oral s…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx
A clinical trial is evaluating dual-energy CT versus MRI for staging or evaluating squamous cell carcinomas of the oral cavity and oropharyn…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Collagen Matrix in Oral Cancer Surgery
Clinical trial evaluating the use of a collagen matrix in oral cancer surgery has completed. The available snippet does not present trial re…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Effectiveness of Hydrogen Water Intervention on Acute Oral Inflammation, Oral Microbiota, and Pain Following Free Flap Reconstruction in Patients With Oral Cancer [NA]
A clinical trial registry entry describing a study of hydrogen-rich water to reduce acute oral inflammation, alter the oral microbiota, and …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Enhancing Oral Cancer Awareness [NA]
A Virginia Commonwealth University-sponsored clinical trial aims to enhance oral cancer awareness using a chatbot for patient education and …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Tirellizumab Combined With TP Neoadjuvant Therapy in the Treatment of Early Oral Squamous Cell Carcinoma （HNC-SYSU-005） [Phase 2]
Phase 2 clinical trial update on Tirellizumab in combination with TP neoadjuvant therapy for early oral squamous cell carcinoma, currently a…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Defining TRPV4 Contribution of Schwann Cells to Oral Cancer Pain [NA]
This clinical trial is recruiting to define how TRPV4 in Schwann cells may contribute to pain in oral squamous cell carcinoma.
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Trial of Nivolumab as a Novel Neoadjuvant Pre-Surgical Therapy for Locally Advanced Oral Cavity Cancer [Phase 2]
A Phase 2 trial evaluated nivolumab as neoadjuvant pre-surgical therapy for locally advanced oral squamous cell carcinoma. The study has com…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Prospective Cohort Study on Oral Microbiome Changes in Patients With Locally Advanced Oral Squamous Cell Carcinoma Following Neoadjuvant Chemoimmunotherapy
Prospective cohort study assessing changes in the oral microbiome of patients with locally advanced oral squamous cell carcinoma after neoad…
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CLINICAL_TRIALS other · 2025-09-18Clinical Trial Update: Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer [NA]
Clinical trial update announcing a study on proactive risk-based optimization and notifications for treatment and outcomes in head and neck …
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection and Drugs-induced Osteonecrosis
A registry is being established to collect data on patients undergoing segmental mandibular defect reconstruction after oral squamous cell c…