Oral Cavity Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial update evaluating either docetaxel plus cetuximab or adding atezolizumab to standard chemotherapy and radiation f…
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: A Fluorescent Tumor Marking Agent, Tozuleristide, for Imaging Oral Cavity Squamous Cell Cancer and High-Grade Oral Cavity Dysplasia During Surgery [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Tozuleristide as a fluorescent tumor marking agent for imaging oral cavity squamous cell carcinoma and…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with cetuximab for recurrent/metastatic head and neck squamous cell carcinoma; the stu…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM) [NA]
A clinical trial evaluating the impact of virtual implant visualization on dosimetry for protecting potential dental implant sites in head a…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck. [Phase 2]
A Phase 2 clinical trial evaluating a peptide-based immunotherapy for head and neck squamous cell carcinoma was terminated; the update repor…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma [Phase 1]
Phase 1 study evaluating IRX-2 regimen with durvalumab for incurable head and neck squamous cell carcinoma has completed, including multiple…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Study Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC [NA]
A completed clinical trial comparing fibula free-flap microreconstruction with or without PVP in patients with oropharyngeal or oral cavity …
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating the addition of M6620 (berzosertib; VX-970) to standard chemotherapy and radiation for head and neck cancers, inclu…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating durvalumab with or without metformin in head and neck squamous cell carcinoma, including oral cavity…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer [EARLY_Phase 1]
Phase 1 trial evaluating durvalumab given before surgery in patients with oral cavity and/or oropharyngeal squamous cell carcinoma; the stud…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin [Phase 1]
Phase 1 trial evaluating the safety and tolerability of Onalespib in combination with radiation therapy and cisplatin for locoregionally adv…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating the combination of pembrolizumab and cabozantinib in head and neck squamous cell carcinoma reported results, with r…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Sentinel Node Biopsy in Early Oral Cancers a Tertiary Cancer Centre Experience [NA]
Completed clinical trial update from Tata Memorial Hospital describing sentinel lymph node biopsy in early oral cavity squamous cell carcino…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating image-guided proton therapy for locally advanced unresectable head an…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: WEE1 Inhibitor with Cisplatin and Radiotherapy: a Trial in Head and Neck Cancer [Phase 1]
Phase 1 trial evaluating a WEE1 inhibitor in combination with cisplatin and radiotherapy for head and neck cancers has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma [Phase 2]
Phase 2 neoadjuvant trial evaluating sintilimab in combination with carboplatin and nab-paclitaxel for resectable oral cavity and oropharyng…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin Followed By Chemoradiation in Treating Patients With Recurrent Head and Neck Cancer [Phase 1]
Phase 1 trial of nab-paclitaxel (albumin-bound paclitaxel) with carboplatin followed by chemoradiation in patients with recurrent head and n…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin [Phase 2]
Phase 2 trial evaluating sodium thiosulfate to prevent cisplatin-induced ototoxicity in patients with head and neck squamous cell carcinoma …
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CLINICAL_TRIALS trial_result · 2024-06-20Clinical Trial Update: Postoperative CCRT With Docetaxel vs Cisplatin in High Risk Oral Cavity Cancer [Phase 2, Phase 3]
This trial compares postoperative concurrent chemoradiation with docetaxel versus cisplatin in high-risk oral cavity squamous cell carcinoma…
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CLINICAL_TRIALS trial_result · 2024-04-01Clinical Trial Update: Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery [Phase 2]
A phase 2 trial evaluated the combination of nivolumab with carboplatin and paclitaxel in patients with stage III-IV head and neck squamous …
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Preoperative TPF Chemotherapy in Molecularly Selected Locally Advanced Resectable Oral Cavity Squamous Cell Cancer [Phase 2]
Phase 2 trial evaluating preoperative TPF chemotherapy in molecularly selected locally advanced resectable oral cavity squamous cell cancer …
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: ACTOplus Met XR in Treating Patients With Stage I-IV Oral Cavity or Oropharynx Cancer Undergoing Definitive Treatment [Phase 2]
Phase 2 clinical trial update for ACTOplus Met XR in patients with stage I-IV oral cavity or oropharyngeal cancer undergoing definitive trea…
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: A Study of Concurrent Chemoradiotherapy Based of Cisplatin With or Without Sintilimab as First-line Therapy for Patients With Advanced Oral Cavity Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating concurrent chemoradiotherapy with cisplatin with or without sintilimab as first-line therapy for advanced …
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Comparison of Adaptive Dose Painting by Numbers With Standard Radiotherapy for Head and Neck Cancer. [Phase 2]
Phase 2 clinical trial comparing adaptive dose painting by numbers with standard radiotherapy for head and neck cancer has completed.
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CLINICAL_TRIALS trial_result · 2022-06-02Clinical Trial Update: Photodynamic Therapy With HPPH Compared to Standard of Care Surgery in Treating Patients With Oral Cavity Cancer [Phase 2]
Phase 2 trial comparing photodynamic therapy with HPPH to standard surgical care in stage I–II oral cavity squamous cell carcinoma was termi…