Opioid Overdose
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Bundled Intervention to End Opioid Overdoses [Phase 4]
This phase 4 clinical trial update outlines a bundled intervention aimed at ending opioid overdoses, to be studied in individuals with opioi…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study [NA]
A Duke University-sponsored clinical trial evaluating a community paramedic response and overdose outreach program with supportive medical-l…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care [NA]
This clinical trial update covers the development and evaluation of a machine-learning tool to predict opioid overdose risk and stratify pat…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Remote Fentanyl Test Strip Distribution and Education to Prevent Drug Overdose [NA]
This clinical trial update describes remote distribution of fentanyl test strips with education to prevent opioid overdose. The study is not…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties [NA]
A clinical trial at Nationwide Children’s Hospital is evaluating an intervention to prevent opioid and fentanyl overdoses in rural and urban…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Quantitative Xylazine Measurement in ED
Completed clinical trial evaluating quantitative measurement of xylazine in emergency department patients. The study, sponsored by Icahn Sch…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Machine-Learning Prediction and Reducing Overdoses With EHR Nudges [NA]
A University of Pittsburgh-led clinical trial is recruiting to test machine-learning predictions and electronic health record nudges intende…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Bundled Intervention [Phase 1, Phase 2]
A bundled intervention is being studied in a Phase 1/Phase 2 clinical trial, sponsored by the University of Alabama at Birmingham, currently…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Model to Save Lives Through a Volunteer First Responder Service Providing Antidote Treatment in Opioid Overdose [NA]
This clinical trial update describes a model to save lives by using volunteer first responders to administer antidote treatment for opioid o…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Vending Machine Naloxone Distribution for Your Community (VENDY) [Phase 4]
Phase 4 trial VENDY is evaluating vending-machine naloxone distribution to support harm reduction in communities; the study is currently rec…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Young Houston Emergency Opioid Engagement System [Phase 4]
Phase 4 clinical trial update for the Young Houston Emergency Opioid Engagement System, sponsored by The University of Texas Health Science …
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: The Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone Distribution [NA]
This clinical trial update reports on the feasibility of using the PulsePoint platform to facilitate overdose education and naloxone distrib…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: UnityPhilly Response App for Overdose Reversal
Drexel University-sponsored clinical trial evaluating the UnityPhilly Response App for opioid overdose reversal is currently not recruiting.
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Improving Access to Naloxone to Prevent Opioid Overdose Deaths (SAIA-Naloxone) [NA]
This clinical trials registry entry updates the SAIA-Naloxone trial (NCT05886712) sponsored by RTI International, which aims to improve acce…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: Naloxone for Opioid Associated Out of Hospital Cardiac Arrest [Phase 2]
Phase 2 clinical trial evaluating Naloxone for opioid-associated out-of-hospital cardiac arrest. Recruitment has not yet begun.
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CLINICAL_TRIALS research · 2024-12-11Clinical Trial Update: Serious Game to Teach Opioid Overdose Response [Phase 2]
A Phase 2 study sponsored by the University of Nevada, Reno is evaluating a serious game to teach opioid overdose response; the trial is not…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Health Insurance Instability and Mortality Among Patients Receiving Bup Tx for OUD
This clinical trial update from Kaiser Permanente examines how health insurance instability affects mortality among patients receiving bupre…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Improving Availability of Intranasal Naloxone [NA]
This clinical trial update describes efforts to improve access to intranasal naloxone for opioid overdose, sponsored by Hartford Hospital.
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CLINICAL_TRIALS research · 2021-07-07Clinical Trial Update: User Acceptability of a Device-Based Opioid Overdose Intervention
A completed clinical trial assessing user acceptability of a device-based intervention for opioid overdose prevention.
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CLINICAL_TRIALS research · 2012-06-20Clinical Trial Update: Naloxone Nasal Spray Pharmacokinetic Study [Phase 1]
This document reports a Phase 1 pharmacokinetic study of naloxone nasal spray sponsored by Mitovie Pharma Ltd for opioid overdose.