Opioid Overdose
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-07Clinical Trial Results: Opioid Rapid Response System: Naloxone Training in Communities [NA]
Completed clinical trial evaluating naloxone training in communities as part of an opioid rapid response system.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Pharmacokinetic (PK) Evaluation of Nalmefene Formulations [Phase 1]
This Phase 1 pharmacokinetic evaluation examines nalmefene formulations for opioid overdose. The study status is completed.
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults [Phase 1]
Phase 1 study assessing pharmacokinetics and safety of multiple doses of intranasal naloxone in healthy adults.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Bundled Intervention to End Opioid Overdoses [Phase 4]
This phase 4 clinical trial update outlines a bundled intervention aimed at ending opioid overdoses, to be studied in individuals with opioi…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The Community Paramedic Response and Overdose Outreach With Supportive Medical-Legal Services Study [NA]
A Duke University-sponsored clinical trial evaluating a community paramedic response and overdose outreach program with supportive medical-l…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care [NA]
This clinical trial update covers the development and evaluation of a machine-learning tool to predict opioid overdose risk and stratify pat…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Remote Fentanyl Test Strip Distribution and Education to Prevent Drug Overdose [NA]
This clinical trial update describes remote distribution of fentanyl test strips with education to prevent opioid overdose. The study is not…
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FDA approval · 2026-04-09FDA Approved: REZENOPY — Supplemental Application (Scienture LLC)
FDA approved a supplemental application for REZENOPY (naloxone HCl) filed by Scienture LLC.
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Preventing Overdose Using Information and Data From the Environment [NA]
Brown University-sponsored trial evaluating a strategy to prevent overdose using environmental information and data. The study is completed …
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorders (PLI-MOUD) [NA]
This completed clinical trial evaluated pharmacist-led interventions to improve access to medications for opioid use disorders. The study wa…
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CLINICAL_TRIALS withdrawal · 2026-04-02Clinical Trial Update: Tailoring Overdose Education for Black Churches [NA]
A clinical trial investigating tailored overdose education for Black churches has been withdrawn.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Evaluating an Intervention to Prevent Overdoses in Rural and Urban Counties [NA]
A clinical trial at Nationwide Children’s Hospital is evaluating an intervention to prevent opioid and fentanyl overdoses in rural and urban…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Quantitative Xylazine Measurement in ED
Completed clinical trial evaluating quantitative measurement of xylazine in emergency department patients. The study, sponsored by Icahn Sch…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Machine-Learning Prediction and Reducing Overdoses With EHR Nudges [NA]
A University of Pittsburgh-led clinical trial is recruiting to test machine-learning predictions and electronic health record nudges intende…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: A Bundled Intervention [Phase 1, Phase 2]
A bundled intervention is being studied in a Phase 1/Phase 2 clinical trial, sponsored by the University of Alabama at Birmingham, currently…
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FDA approval · 2026-02-11FDA Approved: NARCAN — Supplemental Application (Emergent Devices Inc.)
FDA approved a supplemental application for Narcan nasal naloxone (Naloxone hydrochloride nasal) submitted by Emergent Devices Inc.
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Evaluation of a Novel Intervention to Prevent Polysubstance Overdoses Involving Illicit Stimulants [NA]
A completed clinical trial evaluating a novel intervention to prevent polysubstance overdoses involving illicit stimulants, including opioid…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Opioid Rapid Response System: Naloxone Training in Communities [NA]
The study evaluating community Naloxone training as part of an opioid rapid response system has completed.
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FDA approval · 2026-01-09FDA Approved: NARCAN — Supplemental Application (Emergent Devices Inc.)
FDA approved a supplemental application for NARCAN nasal naloxone by Emergent Devices Inc., authorizing an updated version of the product.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Model to Save Lives Through a Volunteer First Responder Service Providing Antidote Treatment in Opioid Overdose [NA]
This clinical trial update describes a model to save lives by using volunteer first responders to administer antidote treatment for opioid o…
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FDA approval · 2025-11-21FDA Approved: NARCAN — Supplemental Application (Emergent Devices Inc.)
FDA approved a supplemental application for Narcan (naloxone hydrochloride nasal spray) from Emergent Devices Inc., representing an addition…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Vending Machine Naloxone Distribution for Your Community (VENDY) [Phase 4]
Phase 4 trial VENDY is evaluating vending-machine naloxone distribution to support harm reduction in communities; the study is currently rec…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Young Houston Emergency Opioid Engagement System [Phase 4]
Phase 4 clinical trial update for the Young Houston Emergency Opioid Engagement System, sponsored by The University of Texas Health Science …
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FDA approval · 2025-08-25FDA Approved: KLOXXADO — Supplemental Application (Hikma Specialty USA Inc.)
The FDA approved a supplemental application for KLOXXADO (naloxone HCl) submitted by Hikma Specialty USA Inc. This action approves a supplem…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: The Rhode Island Prescription and Illicit Drug Study [NA]
Brown University’s Rhode Island Prescription and Illicit Drug Study has completed, and posted its results. The study focused on opioid overd…