Opioid-induced Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation [Phase 3]
A 12-week extension of the Phase III study (D3820C00004) assessed the efficacy and safety of NKTR-118 for opioid-induced constipation in pat…
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation [Phase 3]
A Phase 3 trial update for CB-5945 in opioid-induced constipation has been terminated; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: The Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced Constipation [Phase 3]
Phase 3 trial of CB-5945 for opioid-induced constipation was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: A Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC) [Phase 2]
A Phase 2, double-blind, multiple-dose escalation study evaluated NKTR-118 (oral PEG-naloxol) for opioid-induced constipation, with results …
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation [Phase 3]
A Phase 3 trial by AstraZeneca evaluated the efficacy and safety of a treatment for opioid-induced constipation in patients with non-cancer-…
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Assessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation [Phase 3]
Phase 3 clinical trial assessing efficacy and safety of a treatment for opioid-induced constipation in patients with non-cancer-related pain…
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CLINICAL_TRIALS trial_result · 2015-06-01Clinical Trial Update: Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain [Phase 3]
A Phase 3 trial evaluated efficacy and safety of a treatment for opioid-induced constipation in patients with cancer-related pain. The study…
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: Methylnaltrexone Use for Opioid-induced Postoperative Constipation [Phase 4]
Phase 4 clinical trial update on Relistor (methylnaltrexone) for opioid-induced postoperative constipation. The study status is reported as …
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain [Phase 2]
Phase 2 trial evaluating the efficacy and safety of ADL5945 for opioid-induced constipation in adults on chronic opioid therapy has complete…
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FDA approval · 2015-04-30FDA Approved: RELISTOR — Supplemental Application (Salix Pharmaceuticals, Inc.)
FDA approved a supplemental application for Relistor (methylnaltrexone bromide) from Salix Pharmaceuticals, expanding its labeling for opioi…
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CLINICAL_TRIALS trial_result · 2015-02-12Clinical Trial Update: A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain [Phase 3]
Phase 3 study evaluating analgesic efficacy and opioid-induced constipation management of Oxycodone/Naloxone controlled-release tablets in a…
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation [Phase 3]
AstraZeneca reports long-term safety results from a Phase 3 trial of naloxegol for opioid-induced constipation in adults with non-cancer pai…
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CLINICAL_TRIALS trial_result · 2014-10-20Clinical Trial Update: Assessing a Stool Symptom Screener in Patients With Chronic Opioid-Induced Constipation
This update reports the completion of a clinical trial evaluating a stool symptom screener in patients with chronic opioid-induced constipat…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: Open Label, Healthy Volunteers, Bioequivalence Study With Naloxegol [Phase 1]
Open-label Phase 1 bioequivalence study of naloxegol in healthy volunteers for opioid-induced constipation has been completed.
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FDA approval · 2014-09-16FDA Approved: MOVANTIK — Original Application (RedHill Biopharma Ltd)
FDA approved Movantik (naloxegol oxalate) through an Original Application for the treatment of opioid-induced constipation in adults with ch…
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CLINICAL_TRIALS trial_result · 2013-12-27Clinical Trial Update: Naloxone SR Capsules in Patients With Opioid Induced Constipation [Phase 2]
Phase 2 results update on naloxone sustained-release capsules for opioid-induced constipation in patients with chronic pain, with completed …
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FDA approval · 2013-08-23FDA Approved: RELISTOR — Supplemental Application (Salix Pharmaceuticals, Inc.)
The FDA approved a supplemental application for RELISTOR (METHYLNALTREXONE BROMIDE) from Salix Pharmaceuticals, adding an indication/label u…
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FDA approval · 2013-08-19FDA Approved: LUBIPROSTONE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
FDA approved a supplemental application for Lubiprostone from Dr. Reddy's Laboratories Inc.
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CLINICAL_TRIALS trial_result · 2013-06-26Clinical Trial Update: Prucalopride Effects on Subjects With Chronic Non-cancer Pain Suffering From Opioid Induced Constipation [Phase 3]
Phase 3 trial of prucalopride in subjects with chronic non-cancer pain suffering from opioid-induced constipation was terminated; results po…
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FDA approval · 2013-04-19FDA Approved: LUBIPROSTONE — Supplemental Application (Dr. Reddy's Laboratories Inc.)
FDA approved a supplemental application for Lubiprostone filed by Dr. Reddy's Laboratories Inc.
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CLINICAL_TRIALS trial_result · 2013-02-21Clinical Trial Update: Lubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient Rehabilitation [NA]
This clinical trial compared lubiprostone (Amitiza) to standard care for opioid-induced constipation after surgery in an inpatient rehabilit…
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CLINICAL_TRIALS trial_result · 2012-08-07Clinical Trial Update: ALK37-007: Evaluation of Safety and Efficacy of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC) [Phase 2]
A Phase 2 trial evaluating ALKS 37 (RDC-1036) for opioid-induced constipation in adults has completed.
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: ALK37-005: A Study of ALKS 37 (RDC-1036) in Adults With Opioid-induced Constipation (OIC) [Phase 2]
A Phase 2 study evaluating ALKS 37 (RDC-1036) for opioid-induced constipation in adults has completed.
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain. [Phase 3]
A Phase 3 study evaluating the safety and efficacy of tegaserod for opioid-induced constipation in patients with non-cancer pain has been te…
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CLINICAL_TRIALS trial_result · 2012-04-20Clinical Trial Update: Safety and Efficacy of Tegaserod in Opioid-induced Constipation in Patients With Non-cancer Pain. [Phase 3]
A Phase 3 clinical trial evaluating the safety and efficacy of tegaserod for opioid-induced constipation in patients with non-cancer pain ha…