Opioid-induced Constipation
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-27Clinical Trial Update: A Prospective, Multicenter, Randomized, Parallel-controlled, Superiority Trial [Phase 3]
A Phase 3, prospective multicenter randomized trial evaluating treatment for opioid-induced constipation (OIC) that has not yet started recr…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Electroacupuncture for Opioid-Induced Constipation in Cancer Patients: A Randomized Clinical Trial [NA]
This entry reports the completion of a randomized clinical trial evaluating electroacupuncture for opioid-induced constipation in cancer pat…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Fiber-Enriched Enteral Nutrition and Opioid-Induced Constipation in the ICU
This clinical trial update reports the completion of a study evaluating fiber-enriched enteral nutrition for opioid-induced constipation in …
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Effect of Electroacupuncture on Opioid-induced Constipation in Patients With Cancer [NA]
This clinical trial update reports the completion of a study evaluating electroacupuncture for opioid-induced constipation in cancer patient…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Safety and Preliminary Efficacy of BGP345A in Constipation Due to Opioid-based Medications [Phase 2]
Phase 2 results for BGP345A in opioid-induced constipation show safety signals and preliminary efficacy; the study has completed.
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: European Study of Opioid Induced Constipation
A European clinical trial investigating opioid-induced constipation has completed.
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Prevention of Opioid-induced Constipation in Patients With Advanced Cancer [Phase 4]
Phase 4 clinical trial update on preventing opioid-induced constipation in patients with advanced cancer; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation [Phase 4]
Phase 4 trial comparing methylnaltrexone with naloxegol for opioid-induced constipation has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Naloxegol Drug Utilization Post Authorisation Safety Study
A completed post-authorization safety study assessing real-world naloxegol utilization in patients with opioid-induced constipation.
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Naloxegol Health Outcome Post Authorisation Safety Study
A post-authorization safety study of naloxegol for opioid-induced constipation sponsored by Kyowa Kirin Pharmaceutical Development Ltd has b…
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CLINICAL_TRIALS trial_result · 2024-06-17Clinical Trial Update: Phase I Pharmacokinetics and Safety Study of Naloxegol in Paediatric OIC Patients [Phase 1]
Completed Phase I pharmacokinetics and safety study of Naloxegol in pediatric patients with opioid-induced constipation.
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CLINICAL_TRIALS trial_result · 2023-03-16Clinical Trial Update: Colonic Motor Patterns in Healthy Volunteers [Phase 4]
Phase 4 clinical trial update evaluating colonic motor patterns in healthy volunteers for opioid-induced constipation.
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CLINICAL_TRIALS trial_result · 2021-05-25Clinical Trial Update: A Study of TD-1211 in Subjects With Opioid-Induced Constipation (OIC) [Phase 2]
Phase 2 trial update for TD-1211 in opioid-induced constipation completed.
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CLINICAL_TRIALS trial_result · 2021-05-07Clinical Trial Update: Dose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC) [Phase 2]
Phase 2 dose-ranging study completed assessing SP-333 for opioid-induced constipation (OIC), evaluating safety and efficacy.
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CLINICAL_TRIALS trial_result · 2021-01-25Clinical Trial Update: A Study to Assess the Safety, Tolerability and Clinical Activity of TD-1211 in Patients With Opioid-Induced Constipation [Phase 2]
A Phase 2 clinical trial assessing safety, tolerability, and activity of TD-1211 in patients with opioid-induced constipation has completed.
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: A Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Study to Assess the Safety and Efficacy of TD-1211 in Subjects With Opioid-Induced Constipation [Phase 2]
Phase 2 clinical trial completed evaluating safety and efficacy of TD-1211 for opioid-induced constipation in adults.
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CLINICAL_TRIALS trial_result · 2021-01-20Clinical Trial Update: A Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced Constipation [Phase 1, Phase 2]
A multiple-dose clinical trial update for TD-1211 evaluating safety and pharmacology in healthy volunteers and patients with opioid-induced …
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Study Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant Pain [Phase 2]
Phase 2 clinical trial evaluating oral MOA-728 for treating opioid-induced bowel dysfunction in adults with chronic non-malignant pain; resu…
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CLINICAL_TRIALS trial_result · 2019-11-25Clinical Trial Update: Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain [Phase 2]
Phase 2 trial evaluating oral MOA-728 for opioid-induced bowel dysfunction in chronic non-malignant pain was completed.
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CLINICAL_TRIALS trial_result · 2019-09-06Clinical Trial Update: A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain [Phase 3]
Phase 3 trial evaluating oral methylnaltrexone (MNTX) for treating opioid-induced constipation in adults with chronic non-malignant pain has…
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CLINICAL_TRIALS trial_result · 2019-09-04Clinical Trial Update: Study of Subcutaneous Methylnaltrexone (MNTX) in the Treatment of Opioid-Induced Constipation During Rehabilitation After Orthopedic Procedures [Phase 2]
Phase 2 clinical trial evaluating subcutaneous methylnaltrexone for opioid-induced constipation during rehabilitation after orthopedic surge…
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CLINICAL_TRIALS trial_result · 2019-09-04Clinical Trial Update: Compassionate Use Study of Methylnaltrexone [NA]
Compassionate use study of methylnaltrexone for opioid-induced constipation has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-04-08Clinical Trial Update: Phase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer Pain [Phase 2]
Phase 2 randomized trial evaluating linaclotide for opioid-induced constipation in patients on chronic opioid therapy for non-cancer pain ha…
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CLINICAL_TRIALS trial_result · 2018-11-05Clinical Trial Update: A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy [Phase 4]
Phase 4 clinical trial comparing oxycodone/naloxone with oxycodone after laparoscopic hysterectomy for postoperative pain and opioid-induced…
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CLINICAL_TRIALS trial_result · 2018-09-28Clinical Trial Update: Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation [Phase 3]
Phase 3 clinical trial update for Naloxone HCl PR tablets targeting opioid-induced constipation.