Opioid Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-12Clinical Trial Update: Gabapentin Treatment of Benzodiazepine Abuse in Methadone Maintenance Patients [Phase 2]
Phase 2 trial update on gabapentin for benzodiazepine abuse in methadone-maintained patients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-06-27Clinical Trial Update: A Naturalistic Study of Adolescents and Young Adults in Treatment for Opioid Dependence
Yale University's naturalistic study of adolescents and young adults in treatment for opioid dependence has completed.
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse [Phase 2]
Phase 2 clinical trial update on predictors of relapse for prescription opioid abuse among pain patients.
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CLINICAL_TRIALS trial_result · 2018-05-21Clinical Trial Update: Improved Strategies for Outpatient Opioid Detoxification [Phase 1]
Phase 1 clinical trial evaluating improved outpatient detoxification strategies for opioid dependence has completed. The document notes the …
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CLINICAL_TRIALS trial_result · 2018-04-23Clinical Trial Update: Pilot Test of a Community-based Buprenorphine Treatment Intervention [NA]
This Clinical Trial Update reports on the completion of a pilot community-based buprenorphine treatment intervention for opioid dependence w…
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CLINICAL_TRIALS trial_result · 2018-02-20Clinical Trial Update: Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine [Phase 3]
Phase 3 trial assessing tolerability of depot injections of buprenorphine for opioid use disorder has completed with posted results.
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CLINICAL_TRIALS trial_result · 2018-02-13Clinical Trial Update: The Separate and Combined Effects of Vivitrol and Opiate Abstinence Reinforcement in the Treatment of Opioid Dependence [Phase 2]
Phase 2 trial evaluating the separate and combined effects of Vivitrol (naltrexone extended-release) and opiate abstinence reinforcement in …
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CLINICAL_TRIALS trial_result · 2017-10-30Clinical Trial Update: Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2 [NA]
This completed clinical trial from Johns Hopkins University tested employment-based reinforcement to promote drug abstinence. Participants h…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Study to Evaluate the Exposures of Lofexidine and Its Major Metabolites in Subjects Seeking Buprenorphine Dose Reduction [Phase 1]
A Phase 1 clinical trial update evaluating the exposures of lofexidine and its major metabolites in subjects seeking buprenorphine dose redu…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Main Study of Lofexidine and Methadone Pharmacodynamic Interaction in Methadone Maintained Patients [Phase 1]
Phase 1 trial assessing the pharmacodynamic interaction between lofexidine and methadone in methadone-maintained patients has completed.
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CLINICAL_TRIALS trial_result · 2017-09-06Clinical Trial Update: Glutamatergic Modulation to Facilitate Naltrexone Initiation in Opioid Dependence [Phase 2]
Phase 2 clinical trial investigating glutamatergic modulation to aid initiation of naltrexone in opioid dependence has completed with posted…
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CLINICAL_TRIALS trial_result · 2017-09-06Clinical Trial Update: Nalrexone Facilitated Discontinuation of Buprenorphine [Phase 1, Phase 2]
A Phase 1/2 trial evaluating nalrexone-facilitated discontinuation of buprenorphine in individuals with stable opioid dependence has complet…
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Naltrexone for Opioid Dependent Released Human Immunodeficiency Virus Positive (HIV+) Criminal Justice Populations [Phase 1, Phase 2]
Phase 1/2 trial evaluating naltrexone for opioid dependence in HIV+ criminal justice populations has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Improving Buprenorphine Detoxification Outcomes With Isradipine [Phase 1, Phase 2]
Phase 1 and Phase 2 clinical trials evaluated whether adding isradipine to buprenorphine detoxification improves outcomes for opioid depende…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Efficacy of Levetiracetam in Cocaine-Abusing Methadone Maintained Patients [Phase 2]
Phase 2 trial update evaluating the efficacy of levetiracetam in cocaine-abusing patients maintained on methadone for opioid dependence.
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Usability of Zubsolv Sublingual Tablets 5.7/1.4 to Suboxone Sublingual Film 8/2 In Buprenorphine/Naloxone Treated Opioid Dependent Population [Phase 4]
Phase 4 trial evaluated the usability of Zubsolv Sublingual Tablets (buprenorphine/naloxone) compared with Suboxone Sublingual Film (bupreno…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: A Within Subject Comparison of Opioid Withdrawal in Opioid Dependent Individuals [Phase 1, Phase 2]
A within-subject study evaluating opioid withdrawal in opioid-dependent individuals across Phase 1 and Phase 2, with results posted after co…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Levetiracetam (Keppra) Tolerability in Cocaine Abusing Methadone-maintained Patients. [Phase 2]
Phase 2 trial evaluating tolerability of levetiracetam (Keppra) in cocaine-dependent patients on methadone maintenance completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Effectiveness of Naltrexone and Lofexidine in Treating Detoxified Heroin Addicts - 1 [Phase 1]
A Phase 1 trial sponsored by the National Institute on Drug Abuse evaluated the effectiveness of naltrexone and lofexidine for detoxified op…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Buprenorphine/Naloxone in the Treatment of Heroin Dependence - 14 [Phase 4]
Phase 4 clinical trial evaluating buprenorphine/naloxone for heroin dependence has completed.
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CLINICAL_TRIALS trial_result · 2016-10-10Clinical Trial Update: Cocaine Withdrawal and Pharmacotherapy Response [NA]
Clinical trial update on cocaine withdrawal and pharmacotherapy response; study completed with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled trial evaluating an investigational Indivior compound for cocaine dependence in adult…
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: Methadone Maintenance & HIV Risk in Ukraine [Phase 3]
A Phase 3 clinical trial assessing methadone maintenance and HIV risk reduction among people with opioid dependence in Ukraine has completed…
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CLINICAL_TRIALS trial_result · 2016-08-08Clinical Trial Update: Starting Treatment With Agonist Replacement Therapies Follow-up Study
A follow-up clinical trial on starting treatment with agonist replacement therapies for opioid dependence has completed.
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CLINICAL_TRIALS trial_result · 2016-06-07Clinical Trial Update: Study to Assess Longer-term Opioid Medication Effectiveness (SALOME) [Phase 3]
The SALOME Phase 3 trial evaluating longer-term opioid medication effectiveness for opioid dependence and heroin dependence has completed.