Opioid Dependence
📧 Sign up to get email alerts when something new happens for Opioid Dependence.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: An Innovative Intervention for OUD Treatment [Phase 2, Phase 3]
Phase 2 and Phase 3 clinical trial results for a new intervention in opioid use disorder treatment have been completed, with results posted.
-
CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Update: An Innovative Intervention for OUD Treatment [Phase 2, Phase 3]
Phase 2/3 clinical trial update for an innovative intervention targeting opioid-related disorders, completed with results posted.
-
FDA approval · 2026-04-15FDA Approved: BUPRENORPHINE AND NALOXONE — Supplemental Application (Dr.Reddys Laboratories Inc)
FDA has approved a supplemental application for buprenorphine and naloxone from Dr. Reddy's Laboratories, updating an already approved produ…
-
CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: VK4-116 Phase I Study With Food-Effect [Phase 1]
VK4-116 is entering a Phase I study to evaluate the effect of food on its pharmacokinetics in opioid use disorder and opioid dependence; the…
-
CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery [Phase 4]
A Phase 4 clinical trial is evaluating buprenorphine as a postoperative analgesic for opioid-naive patients after ankle fracture surgery. Th…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis [Phase 1]
A Phase 1 clinical trial at Indiana University is evaluating the safety and tolerability of lacosamide in patients with painful chronic panc…
-
CLINICAL_TRIALS other · 2026-02-18Clinical Trial Update: Measuring Acute Drug Demand in Humans [EARLY_Phase 1]
A suspended early-phase clinical trial (EARLY_Phase 1) conducted by the University of Maryland, Baltimore, investigating acute drug demand i…
-
CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage [Phase 2]
Phase 2 clinical trial evaluating infusion of lidocaine and a corticosteroid into the middle meningeal artery to alleviate pain after aneury…
-
FDA approval · 2025-12-22FDA Approved: BUPRENORPHINE AND NALOXONE — Supplemental Application (Lannett Company, Inc.)
FDA approved a supplemental application for a generic buprenorphine/naloxone product from Lannett Company for the treatment of opioid depend…
-
CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
This clinical trial update indicates a recruiting study assessing long-term maternal and infant outcomes of opioid use disorder during pregn…
-
CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Assessing the Acceptability, Feasibility, Effectiveness and Cost-effectiveness of LADB
This clinical trial update describes a study to assess the acceptability, feasibility, effectiveness and cost-effectiveness of LADB for opio…
-
CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Young Houston Emergency Opioid Engagement System [Phase 4]
Phase 4 clinical trial update for the Young Houston Emergency Opioid Engagement System, sponsored by The University of Texas Health Science …
-
CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children
This clinical trial update reports the pharmacogenomic and pharmacokinetic study of oxycodone to tailor postoperative pain management in ped…
-
CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Brain Mechanisms of Pharmacotherapy in Opioid Use Disorder [Phase 2]
Phase 2 clinical trial update on brain mechanisms of pharmacotherapy for opioid dependence; the study was terminated but results have been p…
-
CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: A Randomized, Double-Blind, Single-Center Clinical Study on the Efficacy of Naltrexone Implant in Antagonizing Opioid Agonist Hydromorphone [Phase 2]
Phase 2 randomized, double-blind study evaluating the efficacy of a naltrexone implant to antagonize the opioid agonist hydromorphone in opi…
-
CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Treatment of Opioid Use: Medication Adherence Therapy [NA]
This entry notes the completion of a clinical trial evaluating Medication Adherence Therapy for opioid dependence and related disorders. Pha…
-
CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Physical Activity as Adjunct Treatment for Opioid Substitution Therapy [NA]
A clinical trial studying physical activity as an adjunct to opioid substitution therapy has been suspended.
-
CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients [NA]
The clinical trial evaluating daily anti-inflammatory supplementation for chronic pain patients on long-term opioids has been terminated.
-
FDA approval · 2025-02-21FDA Approved: BUPRENORPHINE HYDROCHLORIDE AND NALOXONE HYDROCHLORIDE DIHYDRATE — Supplemental Application (Accord Healthcare, Inc)
FDA approved Accord Healthcare's supplemental ANDA for buprenorphine hydrochloride and naloxone hydrochloride dihydrate, a generic product i…
-
CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Impact of Lofexidine on Stress, Craving and Opioid Use [Phase 2]
A Phase 2 trial evaluated lofexidine for its effects on stress, cravings, and opioid use in individuals with opioid use disorder. The study …
-
FDA approval · 2024-10-31FDA Approved: METHADONE HYDROCHLORIDE — Supplemental Application (VistaPharm, LLC)
FDA approved a supplemental application for Methadone Hydrochloride manufactured by VistaPharm, LLC.
-
CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: tDCS to Decrease Opioid Relapse (UG3) [NA]
The UG3 trial evaluating transcranial direct current stimulation (tDCS) to reduce opioid relapse has completed and posted results.
-
FDA approval · 2024-06-12FDA Approved: BUPRENORPHINE HYDROCHLORIDE — Supplemental Application (Hospira, Inc.)
FDA approved Hospira's supplemental application for Buprenorphine Hydrochloride, updating the approved product's labeling and/or specificati…
-
CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Evaluation of Pain Neuroscience Education for Patients Who Experience Chronic Pain With Concurrent Opioid Dependence [NA]
A completed clinical trial from Wichita State University evaluated pain neuroscience education for adults with chronic pain and concurrent o…
-
CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: DE-eSCALation of Opioids Post-surgical dischargE [NA]
This clinical trial investigates strategies for de-escalating opioid use after surgical discharge in individuals with opioid dependence.