Opioid Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: VK4-116 Phase I Study With Food-Effect [Phase 1]
VK4-116 is entering a Phase I study to evaluate the effect of food on its pharmacokinetics in opioid use disorder and opioid dependence; the…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery [Phase 4]
A Phase 4 clinical trial is evaluating buprenorphine as a postoperative analgesic for opioid-naive patients after ankle fracture surgery. Th…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis [Phase 1]
A Phase 1 clinical trial at Indiana University is evaluating the safety and tolerability of lacosamide in patients with painful chronic panc…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
This clinical trial update indicates a recruiting study assessing long-term maternal and infant outcomes of opioid use disorder during pregn…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Assessing the Acceptability, Feasibility, Effectiveness and Cost-effectiveness of LADB
This clinical trial update describes a study to assess the acceptability, feasibility, effectiveness and cost-effectiveness of LADB for opio…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Young Houston Emergency Opioid Engagement System [Phase 4]
Phase 4 clinical trial update for the Young Houston Emergency Opioid Engagement System, sponsored by The University of Texas Health Science …
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Physical Activity as Adjunct Treatment for Opioid Substitution Therapy [NA]
A clinical trial studying physical activity as an adjunct to opioid substitution therapy has been suspended.
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CLINICAL_TRIALS research · 2024-05-02Clinical Trial Update: DE-eSCALation of Opioids Post-surgical dischargE [NA]
This clinical trial investigates strategies for de-escalating opioid use after surgical discharge in individuals with opioid dependence.
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CLINICAL_TRIALS research · 2023-02-10Clinical Trial Update: Improving Effective Contraceptive Use Among Opioid-maintained Women: Stage II [NA]
Clinical trial update on improving effective contraceptive use among women maintained on opioids; status completed with posted results.
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CLINICAL_TRIALS research · 2019-01-07Clinical Trial Update: 5HT3 Antagonists to Treat Opioid Withdrawal and to Prevent the Progression of Physical Dependence [NA]
A completed clinical trial investigating 5HT3 antagonists for treating opioid withdrawal and preventing progression of physical dependence.
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CLINICAL_TRIALS research · 2015-11-23Clinical Trial Update: Study of Integrating Antiretroviral Therapy With Methadone Treatment for People Who Inject Drugs
A clinical trial update examining the integration of antiretroviral therapy with methadone treatment for people who inject drugs.
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CLINICAL_TRIALS research · 2015-09-10Clinical Trial Update: Distress Tolerance and Buprenorphine [Phase 3]
A Phase 3 clinical trial studying distress tolerance with buprenorphine for opioid dependence has completed.
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CLINICAL_TRIALS research · 2013-02-06Clinical Trial Update: An Assessment of Fentanyl Dose Requirements in Opioid-maintained Individuals [NA]
This document provides a clinical trial update evaluating fentanyl dose requirements in individuals maintained on opioids.