Opioid Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: An Innovative Intervention for OUD Treatment [Phase 2, Phase 3]
Phase 2 and Phase 3 clinical trial results for a new intervention in opioid use disorder treatment have been completed, with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Update: An Innovative Intervention for OUD Treatment [Phase 2, Phase 3]
Phase 2/3 clinical trial update for an innovative intervention targeting opioid-related disorders, completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage [Phase 2]
Phase 2 clinical trial evaluating infusion of lidocaine and a corticosteroid into the middle meningeal artery to alleviate pain after aneury…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children
This clinical trial update reports the pharmacogenomic and pharmacokinetic study of oxycodone to tailor postoperative pain management in ped…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Brain Mechanisms of Pharmacotherapy in Opioid Use Disorder [Phase 2]
Phase 2 clinical trial update on brain mechanisms of pharmacotherapy for opioid dependence; the study was terminated but results have been p…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: A Randomized, Double-Blind, Single-Center Clinical Study on the Efficacy of Naltrexone Implant in Antagonizing Opioid Agonist Hydromorphone [Phase 2]
Phase 2 randomized, double-blind study evaluating the efficacy of a naltrexone implant to antagonize the opioid agonist hydromorphone in opi…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Treatment of Opioid Use: Medication Adherence Therapy [NA]
This entry notes the completion of a clinical trial evaluating Medication Adherence Therapy for opioid dependence and related disorders. Pha…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients [NA]
The clinical trial evaluating daily anti-inflammatory supplementation for chronic pain patients on long-term opioids has been terminated.
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Impact of Lofexidine on Stress, Craving and Opioid Use [Phase 2]
A Phase 2 trial evaluated lofexidine for its effects on stress, cravings, and opioid use in individuals with opioid use disorder. The study …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: tDCS to Decrease Opioid Relapse (UG3) [NA]
The UG3 trial evaluating transcranial direct current stimulation (tDCS) to reduce opioid relapse has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Evaluation of Pain Neuroscience Education for Patients Who Experience Chronic Pain With Concurrent Opioid Dependence [NA]
A completed clinical trial from Wichita State University evaluated pain neuroscience education for adults with chronic pain and concurrent o…
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CLINICAL_TRIALS trial_result · 2024-03-01Clinical Trial Update: Collaborative Care for Opioid Dependence And Pain Pilot Study [NA]
A pilot study investigating collaborative care for individuals with opioid dependence and chronic pain was terminated, with results posted i…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Facilitating Rapid Naltrexone Initiation [Phase 3]
Phase 3 clinical trial update on facilitating rapid initiation of naltrexone for opioid dependence; status ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery [Phase 2]
A Phase 2 trial evaluating perioperative ketamine in opioid-tolerant patients undergoing lumbar spine surgery was terminated with results po…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Feasibility and Preliminary Efficacy of an Opioid Stewardship Program in Hospitalized Patients With Chronic Pain [NA]
Feasibility and preliminary efficacy data from a completed clinical trial evaluating an opioid stewardship program in hospitalized patients …
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Remote Observed Dosing of Suboxone to Improve Clinical Practice [Phase 1, Phase 2]
A phase 1/2 trial evaluating remote observed dosing of Suboxone (buprenorphine/naloxone) to inform clinical practice for opioid-use disorder…
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: Treatment for Opioid Dependent Offenders [Phase 2, Phase 3]
Phase 2/3 trial update for a treatment targeting opioid dependence; study completed.
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CLINICAL_TRIALS trial_result · 2023-03-27Clinical Trial Update: Re-entry XR-NTX for Rural Individuals With Opioid Use Disorder [EARLY_Phase 1]
A Phase 1 early trial update for re-entry XR-NTX in rural individuals with opioid use disorder has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: Buprenorphine Treatment for Opioid Dependence [Phase 3]
A Phase 3 clinical trial investigating buprenorphine treatment for opioid dependence has completed.
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CLINICAL_TRIALS trial_result · 2023-01-12Clinical Trial Update: Biomarkers of Injectable Extended Release Naltrexone Treatment [Phase 4]
Phase 4 trial update exploring biomarkers of injectable extended-release naltrexone in heroin and opioid dependence.
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CLINICAL_TRIALS trial_result · 2022-12-15Clinical Trial Update: Comparing Two Training Methods for Opioid Wizard [NA]
A completed clinical trial comparing two training methods related to opioid use disorder/ opioid dependence; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-08-08Clinical Trial Update: Medical Management of Sleep Disturbance During Opioid Tapering [Phase 2]
Phase 2 trial evaluating medical management of sleep disturbance during opioid tapering in opioid dependence/withdrawal.
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: XRB vs. SLB in Jail and at Re-entry: Pilot, Proof of Concept [Phase 4]
Phase 4 pilot trial comparing XRB versus SLB in jail and at re-entry for opioid dependence; completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-07-27Clinical Trial Update: Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction [Phase 2]
Exploratory dose-ranging Phase 2 trial update for APH-1501 in opioid addiction, status not specified.
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis [Phase 4]
Phase 4 clinical trial evaluating continuous sub-fascial bupivacaine infusion and lidocaine patches for analgesia in post-cesarean patients …