Obstructive Hypertrophic Cardiomyopathy
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CLINICAL_TRIALS trial_result · 2026-08-24Clinical Trial Update: A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase III trial update for HRS-1893 in obstructive hypertrophic cardiomyopathy is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM [Phase 3]
Phase 3 trial evaluating aficamten versus metoprolol succinate in adults with obstructive hypertrophic cardiomyopathy has completed with res…
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Update: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM [Phase 3]
Phase 3 trial comparing aficamten to metoprolol succinate in adults with obstructive hypertrophic cardiomyopathy has completed; results post…
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Update: A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 study update evaluating how well aficamten works in Japanese participants with obstructive hypertrophic cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy
The clinical trial update indicates that the mavacamten study in adults with obstructive hypertrophic cardiomyopathy has been completed, wit…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 3]
A Phase 3 clinical trial update reports on aficamten’s evaluation in Japanese patients with symptomatic obstructive hypertrophic cardiomyopa…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: ENABLE-HCM - AI-ENabled Echocardiography With Ultrasound Beyond the Echo Lab for Better HCM Imaging and Expanded Access
The ENABLE-HCM trial evaluating AI-enabled echocardiography for hypertrophic cardiomyopathy imaging has been terminated.
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM [Phase 3]
Cytokinetics reports completion of a Phase 3 trial evaluating aficamten versus placebo in adults with symptomatic obstructive hypertrophic c…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM [Phase 2, Phase 3]
This clinical trial update notes the completion of a long-term safety extension study of mavacamten in adults who completed MAVERICK-HCM or …
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM [Phase 3]
An open-label Phase 3 trial of aficamten in Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Real-World Effectiveness of Mavacamten in Canada
A real-world effectiveness study of mavacamten in Canada has completed, reporting observational data on its use for obstructive hypertrophic…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Mavacamten in Obstructive Hypertrophic Cardiomyopathy
A completed clinical trial evaluating mavacamten for obstructive hypertrophic cardiomyopathy is summarized in this update.
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: A Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy [Phase 2]
Phase 2 clinical trial update for HRS-1893 in patients with Obstructive Hypertrophic Cardiomyopathy; the trial is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM [Phase 3]
A Phase 3 trial evaluating aficamten versus metoprolol succinate in adults with symptomatic obstructive hypertrophic cardiomyopathy has comp…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Safety, Tolerability and Pharmacokinetics Study of CK-3773274 [Phase 1]
Completed Phase 1 safety, tolerability, and pharmacokinetics evaluation of CK-3773274, including subjects with obstructive hypertrophic card…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Trial of HRS-1893 in Healthy Volunteers and Patients With Obstructive Hypertrophic Cardiomyopathy [Phase 1]
Phase 1 clinical trial update indicating the completion of a study of HRS-1893 in healthy volunteers and patients with obstructive hypertrop…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Left Ventricular Mass Index Predicts Clinical Outcomes in Patients with Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy
A completed clinical trial suggests that left ventricular mass index predicts clinical outcomes in patients with obstructive hypertrophic ca…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM [Phase 3]
Phase 3 trial in Chinese adults with symptomatic obstructive hypertrophic cardiomyopathy evaluating mavacamten; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Myocardial Bridging in Obstructive Hypertrophic Cardiomyopathy
A completed clinical trial from Chinese Academy of Medical Sciences/Fuwai Hospital evaluating myocardial bridging in obstructive hypertrophi…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Percutaneous Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy in Children
The pediatric trial of percutaneous intramyocardial septal radiofrequency ablation for obstructive hypertrophic cardiomyopathy has completed…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects [Phase 1]
This Phase 1 study evaluated the effect of verapamil tablets on the pharmacokinetics of HRS-1893 tablets in healthy subjects and has complet…
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CLINICAL_TRIALS trial_result · 2021-10-04Clinical Trial Update: Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 clinical study evaluating mavacamten (MYK-461) in adults with symptomatic obstructive hypertrophic cardiomyopathy has completed; res…
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CLINICAL_TRIALS trial_result · 2014-12-19Clinical Trial Update: Effects of Continous Positive Airway Pressure (CPAP) in Hypertrophic Cardiomyopathy [NA]
A completed clinical trial evaluating continuous positive airway pressure (CPAP) in patients with hypertrophic cardiomyopathy, including bot…