Obstructive Hypertrophic Cardiomyopathy
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CLINICAL_TRIALS trial_result · 2026-08-24Clinical Trial Update: A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase III trial update for HRS-1893 in obstructive hypertrophic cardiomyopathy is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Results: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM [Phase 3]
Phase 3 trial evaluating aficamten versus metoprolol succinate in adults with obstructive hypertrophic cardiomyopathy has completed with res…
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Update: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM [Phase 3]
Phase 3 trial comparing aficamten to metoprolol succinate in adults with obstructive hypertrophic cardiomyopathy has completed; results post…
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Update: A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 study update evaluating how well aficamten works in Japanese participants with obstructive hypertrophic cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy
The clinical trial update indicates that the mavacamten study in adults with obstructive hypertrophic cardiomyopathy has been completed, wit…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 3]
A Phase 3 clinical trial update reports on aficamten’s evaluation in Japanese patients with symptomatic obstructive hypertrophic cardiomyopa…
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CLINICAL_TRIALS trial_result · 2026-03-09Clinical Trial Update: ENABLE-HCM - AI-ENabled Echocardiography With Ultrasound Beyond the Echo Lab for Better HCM Imaging and Expanded Access
The ENABLE-HCM trial evaluating AI-enabled echocardiography for hypertrophic cardiomyopathy imaging has been terminated.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER) [Phase 4]
A Phase 4 clinical trial in India evaluating mavacamten for symptomatic obstructive hypertrophic cardiomyopathy is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM [Phase 3]
Cytokinetics reports completion of a Phase 3 trial evaluating aficamten versus placebo in adults with symptomatic obstructive hypertrophic c…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Biological Collection for the Purpose of Exploring Genetic and Clinical-biological Factors Associated With Variability in Response to Mavacamten in the Treatment of Obstructive Hypertrophic Cardiomyopathy
This clinical trial update describes a biological sample collection study to explore genetic and clinical-biological factors that influence …
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM [Phase 2, Phase 3]
This clinical trial update notes the completion of a long-term safety extension study of mavacamten in adults who completed MAVERICK-HCM or …
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan
This Clinical Trial Update reports that a post-marketing surveillance study of mavacamten in Japanese patients with obstructive hypertrophic…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM [Phase 3]
An open-label Phase 3 trial of aficamten in Chinese patients with symptomatic obstructive hypertrophic cardiomyopathy has completed.
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Real-World Effectiveness of Mavacamten in Canada
A real-world effectiveness study of mavacamten in Canada has completed, reporting observational data on its use for obstructive hypertrophic…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
A prospective registry study evaluating real-world patient characteristics, treatment patterns, and outcomes in obstructive hypertrophic car…
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Mavacamten in Obstructive Hypertrophic Cardiomyopathy
A completed clinical trial evaluating mavacamten for obstructive hypertrophic cardiomyopathy is summarized in this update.
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy [Phase 3]
A Phase III clinical trial evaluating HRS-1893 for obstructive hypertrophic cardiomyopathy is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Study to Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US
A clinical trial update indicates that a study evaluating mavacamten for obstructive hypertrophic cardiomyopathy in the United States is cur…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: A Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy [Phase 2]
Phase 2 clinical trial update for HRS-1893 in patients with Obstructive Hypertrophic Cardiomyopathy; the trial is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM [Phase 3]
A Phase 3 trial evaluating aficamten versus metoprolol succinate in adults with symptomatic obstructive hypertrophic cardiomyopathy has comp…
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FDA approval · 2025-04-17FDA Approved: CAMZYOS — Supplemental Application (Myokardia, Inc.)
The FDA approved a supplemental application for CAMZYOS (mavacamten) from Myokardia, Inc., marking an approved update to its labeling or ind…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Efficacy of Mavacamten Combined With Radiofrequency Ablation in Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy [NA]
A clinical trial update describes a planned study to evaluate mavacamten in combination with radiofrequency ablation for symptomatic obstruc…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Safety, Tolerability and Pharmacokinetics Study of CK-3773274 [Phase 1]
Completed Phase 1 safety, tolerability, and pharmacokinetics evaluation of CK-3773274, including subjects with obstructive hypertrophic card…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: Real-world Patient Reported Outcomes Among Patients Treated With Camzyos
This clinical trial update reports planned real-world patient-reported outcomes for individuals treated with Camzyos (mavacamten) in obstruc…
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: A Study to Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy
This clinical trial update indicates that a study evaluating the safety of mavacamten in Korean patients with symptomatic obstructive hypert…