Obstructive Hypertrophic Cardiomyopathy
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-06Clinical Trial Update: Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM
Clinical trial update for mavacamten in obstructive hypertrophic cardiomyopathy. The study investigates the effect on coronary flow reserve …
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: A Trial of HRS-1893 in Healthy Volunteers and Patients With Obstructive Hypertrophic Cardiomyopathy [Phase 1]
Phase 1 clinical trial update indicating the completion of a study of HRS-1893 in healthy volunteers and patients with obstructive hypertrop…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Left Ventricular Mass Index Predicts Clinical Outcomes in Patients with Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy
A completed clinical trial suggests that left ventricular mass index predicts clinical outcomes in patients with obstructive hypertrophic ca…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCM [Phase 3]
Phase 3 trial in Chinese adults with symptomatic obstructive hypertrophic cardiomyopathy evaluating mavacamten; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Myocardial Bridging in Obstructive Hypertrophic Cardiomyopathy
A completed clinical trial from Chinese Academy of Medical Sciences/Fuwai Hospital evaluating myocardial bridging in obstructive hypertrophi…
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Percutaneous Intramyocardial Septal Radiofrequency Ablation for Obstructive Hypertrophic Cardiomyopathy in Children
The pediatric trial of percutaneous intramyocardial septal radiofrequency ablation for obstructive hypertrophic cardiomyopathy has completed…
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CLINICAL_TRIALS trial_result · 2024-06-06Clinical Trial Update: Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects [Phase 1]
This Phase 1 study evaluated the effect of verapamil tablets on the pharmacokinetics of HRS-1893 tablets in healthy subjects and has complet…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Percutaneous Endocardial Septal Radiofrequency Ablation in Obstructive Hypertrophic Cardiomyopathy [NA]
Clinical trial update describing percutaneous endocardial septal radiofrequency ablation for obstructive hypertrophic cardiomyopathy.
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CLINICAL_TRIALS research · 2024-05-06Clinical Trial Update: Assessment of Cardiac Function, Microvascular Function and Cardiac Perfusion in Different Disease Stages of Hypertrophic Cardiomyopathy
A clinical trial evaluating cardiac function, microvascular function, and cardiac perfusion across disease stages in hypertrophic cardiomyop…
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FDA approval · 2023-12-19FDA Approved: CAMZYOS — Supplemental Application (Myokardia, Inc.)
FDA approved a supplemental application for Camzyos (mavacamten) from Myokardia, Inc., advancing regulatory action related to the drug.
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FDA approval · 2022-04-28FDA Approved: CAMZYOS — Original Application (Myokardia, Inc.)
FDA approved CAMZYOS (mavacamten) from MyoKardia for adults with symptomatic obstructive hypertrophic cardiomyopathy, marking a new mechanis…
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CLINICAL_TRIALS trial_result · 2021-10-04Clinical Trial Update: Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy [Phase 3]
Phase 3 clinical study evaluating mavacamten (MYK-461) in adults with symptomatic obstructive hypertrophic cardiomyopathy has completed; res…
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CLINICAL_TRIALS trial_result · 2014-12-19Clinical Trial Update: Effects of Continous Positive Airway Pressure (CPAP) in Hypertrophic Cardiomyopathy [NA]
A completed clinical trial evaluating continuous positive airway pressure (CPAP) in patients with hypertrophic cardiomyopathy, including bot…