Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating XP-102 in combination with trametinib for BRAF V600-mutant advanced solid tumors; the study is not yet…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Clinical Trial of AMG510 in Stage III Unresectable NSCLC KRAS p.G12C Patients and Ineligible for Chemo-radiotherapy [Phase 2]
Phase 2 clinical trial update for AMG510 (sotorasib) in patients with unresectable stage III non-small cell lung cancer harboring KRAS G12C …
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CLINICAL_TRIALS withdrawal · 2025-04-10Clinical Trial Update: A2R and Ectonucleotidases Expression in Lung Cancer Circulating Tumor Cells
A clinical trial evaluating A2R and ectonucleotidases expression in circulating tumor cells from non-small cell lung cancer has been withdra…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Personalizing Adoptive Cell Transfer for Solid Tumors: Towards a New Patient-tailored Treatment Option
The study outlines a personalized adoptive cell transfer approach for solid tumors, including non-small cell lung cancer. It is currently no…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Phase 1b/2a, Open-label Study of Vactosertib in Combination With Durvalumab in Advanced NSCLC [Phase 1, Phase 2]
An open-label phase 1b/2a trial evaluating Vactosertib in combination with Durvalumab for advanced/metastatic non-small cell lung cancer has…
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CLINICAL_TRIALS trial_result · 2025-04-10Clinical Trial Update: Ultrasound-guided Cryobiopsy of Mediastinal/Hilar Lymph Nodes [NA]
A clinical trial update reports ultrasound-guided cryobiopsy of mediastinal and hilar lymph nodes in non-small cell lung cancer and indicate…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Lung Cancer Registry
A ClinicalTrials.gov registry entry for the Lung Cancer Registry (NCT04654364) shows the study is currently recruiting. The conditions inclu…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: MYLUNG Consortium Study Protocol 2
Update on the MYLUNG Consortium Study Protocol 2 for non-small cell lung cancer; the study is listed as active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO) [Phase 2]
This document reports a Phase 2 clinical trial update examining atezolizumab in combination with induction chemotherapy and radiotherapy for…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Real-world Experience With Combination Chemotherapy and Osimertinib in Poor Prognostic Group of Metastatic EGFR-mutated Lung Adenocarcinoma [Phase 2]
Phase 2 clinical trial evaluating the combination of chemotherapy with osimertinib in metastatic EGFR-mutated non-small cell lung cancer (lu…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Nivolumab and Ipilimumab Plus Chemotherapy for Patients With Stage IV Lung Cancer With Brain Metastases [Phase 2]
A Phase 2 trial of nivolumab and ipilimumab with chemotherapy for stage IV non-small cell lung cancer with brain metastases is currently act…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: NADIM II: Neo-Adjuvant Immunotherapy [Phase 2]
NADIM II is a Phase 2 neoadjuvant immunotherapy trial for non-small cell lung cancer; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors [Phase 1]
This document describes a Phase Ib trial of HS-20117 in combination with other drugs for advanced solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Glumetinib Combined With Osimertinib Mesylate Versus Platinum-based Doublet Chemotherapy in Non-Small Cell Lung Cancer Patients After Resistance to EGFR-TKIs [Phase 3]
Phase 3 clinical trial evaluating Glumetinib in combination with Osimertinib Mesylate versus platinum-based chemotherapy in non-small cell l…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: RaFIST: A Radiomics-Based Tool for Intratumoral Fibrosis Stratification in Non-Small Cell Lung Cancer
This document reports the completion of a clinical trial evaluating RaFIST, a radiomics-based tool for stratifying intratumoral fibrosis in …
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CLINICAL_TRIALS withdrawal · 2025-04-08Clinical Trial Update: Predictive Value of PET/CT for Efficacy of Neoadjuvant Immunotherapy in Non-small Cell Lung Cancer
A clinical trial investigating PET/CT as a predictor of neoadjuvant immunotherapy efficacy in non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: AB-16B5 Combined With Docetaxel in Subjects With Metastatic Non-Small Cell Lung Cancer (EGIA-002) [Phase 2]
This clinical trial update reports results from a Phase 2 study of AB-16B5 in combination with docetaxel for metastatic non-small cell lung …
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Priming Immunotherapy in Advanced Disease With Radiation [Phase 2]
This is a Phase 2 clinical trial update evaluating priming immunotherapy in combination with radiation for advanced disease. Results have be…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation [Phase 1]
Phase 1 study of MRTX1133 in KRAS G12D-mutant solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Neoadjuvant Anti PD-1 Immunotherapy in Resectable Non-small Cell Lung Cancer [Phase 2]
This Phase 2 neoadjuvant study of anti-PD-1 immunotherapy in resectable non-small cell lung cancer has completed enrollment and posted resul…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Phase 1/2a Study of JAB-21822 Plus JAB-3312 in Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation [Phase 1, Phase 2]
An early-phase Phase 1/2a trial evaluating the combination of JAB-21822 and JAB-3312 in KRAS p.G12C-mutant advanced solid tumors, including …
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: A Study of JAB-21822 in Advanced or Metastatic NSCLC With KRAS p.G12C and STK11 Co-mutation and Wild-type KEAP1 [Phase 1, Phase 2]
Phase 1/2 study of JAB-21822 in advanced or metastatic non-small cell lung cancer with KRAS p.G12C and STK11 co-mutation and KEAP1 wild-type…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Study of XB002 in Subjects With Solid Tumors (JEWEL-101) [Phase 1]
JEWEL-101 is a Phase 1 trial of XB002 in patients with solid tumors, covering multiple indications. The study has completed.
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy [Phase 3]
A Phase 3 trial comparing furmonertinib to placebo in EGFR mutation-positive stage II-IIIA non-small cell lung cancer after complete resecti…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer [Phase 2]
Phase 2 trial evaluating dose-attenuated chemotherapy in compromised patients with lung cancer is currently recruiting. The study includes b…