Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC [Phase 2]
Overview of a Phase 2 trial comparing local consolidative radiation therapy added to a tyrosine kinase inhibitor versus TKI alone in driver-…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Efficacy of Neoadjuvant Immunotherapy in Patients With Lung Cancer
An ongoing clinical trial from the Chinese Academy of Medical Sciences is evaluating the efficacy of neoadjuvant immunotherapy in patients w…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Phase 2 Clinical Study of Combination Therapy With ABSK043 and Glecirasib [Phase 2]
A Phase 2 clinical trial evaluating ABSK043 in combination with Glecirasib for non-small cell lung cancer is not yet recruiting.
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors [Phase 1]
Phase 1 trial update evaluating AB248 alone or with pembrolizumab in adults with solid tumors, including non-small cell lung cancer, melanom…
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CLINICAL_TRIALS withdrawal · 2025-09-10Clinical Trial Update: Concomitant Chemo-radiotherapy in Locally Advanced Non Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating concomitant chemo-radiotherapy for locally advanced non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 trial evaluating Belrestotug plus dostarlimab vs placebo plus pembrolizumab in untreated PD-L1-high non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC [Phase 3]
This is a Phase 3 clinical trial comparing Standard Maintenance Therapy alone versus SMT plus local consolidative radiation therapy in oligo…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette Use [NA]
Completed clinical trial evaluating an enhanced tobacco intervention protocol versus standard treatment to reduce cigarette use in patients …
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Phase I/II Study of Hypofractionated Proton Therapy for Stage II-III Non-Small Cell Lung Cancer [Phase 1, Phase 2]
This clinical trial update describes a Phase I/II study evaluating hypofractionated proton therapy for stage II-III non-small cell lung canc…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Pharmacokinetic Study of QL2107 Versus Keytruda® for Adjuvant Therapy of Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
This document outlines a Phase 3 pharmacokinetic comparison trial evaluating QL2107 versus Keytruda (pembrolizumab) as adjuvant therapy for …
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression [Phase 1, Phase 2]
A2 Biotherapeutics is evaluating A2B395, an allogeneic logic-gated CAR T therapy, in Phase 1/2 trials for solid tumors expressing EGFR and l…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study of NX-1607 in Adults With Advanced Malignancies [Phase 1]
A Phase 1 study evaluating NX-1607 in adults with advanced malignancies is actively recruiting across multiple tumor types, including ovaria…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study on the Efficacy of Androgen Deprivation Therapy Combined With Anti-PD-1 Therapy in Advanced Lung Cancer [NA]
Clinical trial recruitment is ongoing for a study evaluating androgen deprivation therapy combined with anti-PD-1 therapy in advanced non-sm…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 study comparing atezolizumab plus tiragolumab versus durvalumab in locally advanced, unresectable stage III non-small cell lung canc…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: AK112 in Non-squamous Non-small Cell Lung Cancer (NSCLC)Patients With Actionable Genomic Alterations (AGA) Who Have Failed to Previous Tyrosine Kinase Inhibitor (TKI) Treatment [Phase 2]
Clinical trial update for AK112 in non-squamous non-small cell lung cancer with actionable genomic alterations after TKI failure; Phase 2, n…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: A Study to Assess the Efficacy of WSD0922-FU in Patients With C797S+ Advanced Non-small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating WSD0922-FU in C797S+ advanced non-small cell lung cancer; currently recruiting.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Thoracic Radiotherapy for Patients With Metastatic (Stage IV) Non-Small Cell Lung Cancer at High Risk of Symptomatic Progression Within the Thorax [Phase 2]
A Phase 2 trial evaluating thoracic radiotherapy for metastatic stage IV non-small cell lung cancer at high risk of symptomatic thoracic pro…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Immune-Marker Platform for Patients With Advanced Lung Cancer
A clinical trial update describes an immune-marker platform being studied in advanced non-small cell lung cancer; the study is not yet recru…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Nanocrystalline Megestrol Acetate in Concurrent Chemoradiotherapy for Locally Advanced Non-Small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial evaluating nanocrystalline megestrol acetate combined with concurrent chemoradiotherapy for locally advanced non-smal…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Dacomitinib in Lung Cancer With Uncommon EGFR Mutations [Phase 2]
A Phase 2 clinical trial evaluating dacomitinib in metastatic non-small cell lung cancer with uncommon EGFR mutations is currently active bu…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Athletic Intervention After THoracic surgEry for luNg cAncer: a Pilot Study [NA]
A pilot clinical trial is investigating an athletic intervention after thoracic surgery for non-small cell lung cancer. The study status is …
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: A Phase I/II Study of WJ13404 Monotherapy in Patients With Advanced or Mentastatic Non-Small Cell Lung Cancer [Phase 1, Phase 2]
Phase I/II study of WJ13404 as monotherapy for locally advanced or metastatic non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: START: Safety and Anti-Tumor Activity of PeptiCRAd-1 in Treatment of Cancer [Phase 1]
Phase 1 trial update of PeptiCRAd-1 reports safety signals and anti-tumor activity across multiple cancers; trial status is ACTIVE_NOT_RECRU…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors [Phase 1]
Phase 1 first-in-human trial evaluating OKN4395 in combination with pembrolizumab in patients with solid tumors is currently recruiting. The…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC [Phase 2]
This is a Phase 2 clinical trial evaluating toripalimab in combination with cryoablation as first-line therapy for driver-negative advanced …