Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Brigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLC [Phase 1]
Phase 1 clinical trial update for Brigatinib plus Bevacizumab in ALK-rearranged non-small cell lung cancer (locally advanced to metastatic/r…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: ALG-LungCancerRegistry (SAFRO2202)
An ongoing clinical trial registry in Algeria (SAFRO2202) for lung cancer is recruiting patients with non-small cell lung cancer, small cell…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Ph I/II Trial of Systemic VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors [Phase 1, Phase 2]
An ongoing Phase 1/2 study investigates systemic VSV-IFNβ-NIS in combination with checkpoint inhibitors for select solid tumors. The trial i…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Primary Tumor Resection Plus Osimertinib in Advanced EGFR-mutant Non-small Cell Lung Cancer [Phase 2]
This clinical trial update describes a Phase 2 study of adding primary tumor resection to osimertinib in advanced EGFR-mutant non-small cell…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Primary Tumor Resection With Sintilimab and Chemotherapy in Advanced NSCLC [Phase 2]
Phase 2 trial investigating primary tumor resection with sintilimab and chemotherapy in advanced non-small cell lung cancer; the study is no…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Sequencing of Stereotactic Ablative Body Radiotherapy in Combination With PD-1 Blockade Using Pembrolizumab in Metastatic Non-Small Cell Lung Carcinoma [Phase 1]
Phase 1 trial evaluating sequencing of stereotactic ablative body radiotherapy with pembrolizumab in metastatic non-small cell lung cancer h…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: SRS for NSCLC With Oligo-residual Intracranial Disease After First-line 3rd Generation EGFR-TKI [Phase 2]
Clinical trial update on stereotactic radiosurgery for brain metastases in non-small cell lung cancer after a first-line third-generation EG…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Special Drug Use-results Surveillance of Tabrecta Tablets
The document reports results from Special Drug Use surveillance of Tabrecta (capmatinib) tablets in non-small cell lung cancer, with the stu…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: First-line Immunotherapy-based Standard of Care and Local Ablative Treatments for Oligometastatic Non-small Cell Lung Cancer Patients. [Phase 3]
A Phase 3 trial is investigating upfront immunotherapy-based standard of care combined with local ablative therapies for oligometastatic non…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Deciphering Mechanisms Underlying Cancer Immunogenicity [NA]
A clinical trial exploring mechanisms underlying cancer immunogenicity, sponsored by Institut Claudius Regaud; the study is currently recrui…
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: A Study of GI-108, an Anti-CD73-IgG4 Fc-IL-2v Bispecific Fusion Protein, as Monotherapy in Patients With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial update for GI-108, a bispecific anti-CD73-IL-2v fusion protein, being studied as monotherapy in advanced or metasta…
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CLINICAL_TRIALS other · 2025-09-15Clinical Trial Update: Serplulimab Combined With Cryoablation for Early-Stage Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating serplulimab in combination with cryoablation for early-stage non-small cell lung cancer; the study status is not …
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: A Real-world Study of Adebrelimab-based Combination Regimens in the Treatment of Advanced Solid Tumors
Real-world study evaluating adebrelimab-based combination regimens for advanced solid tumors. The conditions include non-small cell lung can…
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CLINICAL_TRIALS withdrawal · 2025-09-15Clinical Trial Update: Neoadjuvant KRAS G12C Directed Therapy With Adagrasib (MRTX849) With or Without Nivolumab [Phase 2]
Phase 2 neoadjuvant trial of adagrasib (MRTX849) with or without nivolumab in resectable non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: A Study of YL202 in Combination With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of YL202 in combination with other anti-tumor therapies for patients with advanced soli…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors [Phase 1]
Phase 1a/1b study of TPST-1495 as monotherapy and in combination with pembrolizumab has completed status, spanning multiple solid tumors inc…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: A Retrospective Observational Study of Nivolumab in Combination With Chemotherapy as Neoadjuvant Therapy for Resectable NSCLC Patients: Real-World Experience in Taiwan (NEOREAL)
An observational real-world study from Taiwan is evaluating nivolumab in combination with chemotherapy as neoadjuvant therapy for resectable…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Robotic Lobectomy vs. Thoracoscopic Lobectomy for Early Stage Lung Cancer: RCT [NA]
A randomized trial comparing robotic lobectomy with thoracoscopic lobectomy for early-stage non-small cell lung cancer; the study status is …
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Real-World Study on Gene Profile in Patients With Advanced NSCLC Who Progressed on First-Line Osimertinib Therapy(GPS). [Phase 4]
Phase 4 real-world study assessing gene profiles in patients with advanced non-small cell lung cancer who progressed on first-line osimertin…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Fissios© and Postoperative Complications (FPoC Trial) [NA]
This document provides an update on the Fissios© Postoperative Complications (FPoC) Trial, sponsored by Carlos Alfredo Fraile Olivero, MD, P…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial [Phase 2]
This entry announces a Phase II randomized, double-blind trial of RMT in combination with Durvalumab and chemotherapy in untreated non-small…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Personalized SBRT in Early-Stage Peripheral NSCLC [Phase 2]
This is a Phase 2 clinical trial update for personalized SBRT in early-stage peripheral non-small cell lung cancer, currently enrolling by i…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Immunotherapy Clearance and Phenotype of Circulating Tumor Cells in Lung and Head and Neck Cancers [NA]
Clinical trial update on immunotherapy and circulating tumor cell phenotyping in metastatic non-small cell lung cancer and metastatic head a…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT [Phase 3]
A Phase III randomized trial is evaluating upfront cranial radiotherapy versus observation in patients with oncogene-mutated non-small cell …
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: First Line Treatment in EGFR Mutation Positive Advanced NSCLC Patients With Central Nervous System (CNS) Metastases [Phase 2, Phase 3]
Clinical trial update indicating the completion of a Phase 2/3 study evaluating first-line treatment for EGFR mutation-positive advanced non…