Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Collecting and Analyzing Tissue Samples From Patients Undergoing Surgery for Non-Small Cell Lung Cancer
A clinical trial update describing the collection and analysis of tissue samples from patients undergoing surgery for non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC. [Phase 2]
Phase 2 clinical trial evaluating SI-B001 in combination with chemotherapy for EGFR/ALK wild-type recurrent or metastatic non-small cell lun…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of SI-B001+SI-B003± Chemotherapy in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer [Phase 1, Phase 2]
A phase 1/2 trial evaluating SI-B001 with or without SI-B003 and chemotherapy for locally advanced or metastatic non-small cell lung cancer …
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CLINICAL_TRIALS label_change · 2025-09-26Clinical Trial Update: A Study on Using SFRT With Standard Treatment for Oligoprogressive NSCLC [Phase 2]
This Phase 2 clinical trial investigates SFRT with standard treatment for oligoprogressive non-small cell lung cancer and is currently recru…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating bemcentinib in combination with pembrolizumab in advanced non-small cell lung cancer has completed enrollment and p…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC [Phase 2]
A Phase 2 safety and efficacy study of CAB-AXL-ADC in adults with non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: A Phase IB/II Study of Alectinib Combined With Cobimetinib in Advanced ALK-Rearranged (ALK+) NSCLC [Phase 1, Phase 2]
Clinical trial update describing a Phase 1b/Phase 2 study evaluating the combination of Alectinib and Cobimetinib in adults with advanced AL…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: EXL01 in Combination With Nivolumab for Advanced NSCLC Refractory to Immunotherapy. [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating EXL01 in combination with Nivolumab for advanced non-small cell lung cancer refractory to immunothe…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Osimertinib for Advanced EGFR-positive NSCLC Patients
A clinical trial is evaluating Osimertinib for advanced EGFR-positive non-small cell lung cancer and the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C) [Phase 1, Phase 2]
This clinical trial update reports Eli Lilly's KRAS G12C inhibitor LY3537982 is being studied in Phase 1/2 trials across multiple KRAS G12C-…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Postbiotics Ameliorate Cachexia in Patients With Non-small-cell Lung Cancer [NA]
Clinical trial update indicating postbiotics are being studied to ameliorate cachexia in patients with non-small cell lung cancer, with the …
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Sacituzumab Tirumotecan in Combination With Furmonertinib as Second-line Treatment for EGFR-mutant Advanced or Metastatic NSCLC After Failure of First-line Third-generation EGFR-TKI Therapy [Phase 2]
A Phase 2 clinical trial is evaluating sacituzumab govitecan in combination with furmonertinib as second-line therapy for EGFR-mutant advanc…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation [Phase 1]
Phase 1 dose-escalation study of HBI-2438 in KRAS G12C-mutant solid tumors; the trial is active but not recruiting and targets indications i…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Lorlatinib After Failure of First-line TKI in Patients With Advanced ROS1-positive NSCLC (ALBATROS) [Phase 2]
Phase 2 clinical trial update on lorlatinib for patients with metastatic ROS1-positive non-small cell lung cancer after failure of first-lin…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: First-line Therapy With Nivolumab Plus Ipilimumab in Combination With Chemotherapy for Metatastatic NSCLC (NICReWo Trial)
Clinical trial update describing a first-line strategy for metastatic non-small cell lung cancer using nivolumab plus ipilimumab in combinat…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Cadonilimab(AK104) Plus Concurrent Chemoradiotherapy in Patients With Locally Advanced, Unresectable, Stage III NSCLC [Phase 2]
Phase 2 study evaluating Cadonilimab (AK104) with concurrent chemoradiotherapy in locally advanced, unresectable stage III non-small cell lu…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Immunodynamics-Guided Optimization of Individualized Immunochemotherapy in Advanced Driver-Negative NSCLC: A Randomized Trial [Phase 1, Phase 2]
Phase 1/2 randomized trial evaluating immunodynamics-guided optimization of individualized immunochemotherapy for advanced driver-negative n…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations [Phase 1]
A Phase 1 dose-escalation trial of an SHP2 inhibitor in patients with solid tumors harboring KRAS or EGFR mutations is currently active and …
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Impact of Dysbiosis-inducing Drugs on Effectivity of Immune Checkpoint Inhibitor in Non-small Cell Lung Cancer Patients
A clinical trial update describes a study investigating whether dysbiosis-inducing drugs influence the effectiveness of an immune checkpoint…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Neoadjuvant Immunotherapy in Early Stage Non-small-cell Lung Cancer Presenting as Synchronous Ground-glass Nodules [Phase 2]
Phase 2 neoadjuvant immunotherapy trial in early-stage non-small cell lung cancer presenting as synchronous ground-glass nodules has complet…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: A Study to Evaluate SHR-1210 in Combination With Famitinib Plus Chemotherapy in Subjects With NSCLC. [Phase 3]
Phase 3 trial evaluating SHR-1210 with Famitinib and chemotherapy in non-squamous non-small-cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: EBUS TBNA After PET/CT in Diagnosing Patients With Stage I-IIA Non-small Cell Lung Cancer Evaluated for Stereotactic Body Radiation Therapy
Clinical trial update on using endobronchial ultrasound-guided transbronchial needle aspiration after PET/CT to improve diagnosis in patient…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a peptide vaccine to prevent acquired resistance in patients with advanced ALK-positive non-small c…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: The Role of DNA and RNA in NGS Analyses for Advaced Stage NSCLC Patients [NA]
The trial investigates the role of DNA and RNA sequencing in NGS analyses for advanced-stage non-small cell lung cancer. Recruitment is curr…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Perioperative and Postoperative Circulating Tumor Cell Monitoring in Different Stage of NSCLC
This completed clinical trial evaluated perioperative and postoperative circulating tumor cell monitoring across different stages of non-sma…