Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: A Phase II Study of QL1706 and Platinum-Based Chemotherapy in Patients With SMARCA4-Deficient, Locally Advanced or Metastatic Non-Small Cell Lung Cancer. [Phase 2]
Phase II trial update for QL1706 combined with platinum-based chemotherapy in SMARCA4-deficient locally advanced or metastatic non-small cel…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Pragmatic Analysis of Complex Radiotherapy Cases In Cancer of the Lung
A clinical trial registry entry describing a pragmatic analysis of complex radiotherapy cases in lung cancer (non-small cell and small cell)…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET [Phase 1]
Phase 1 study of TPX-0022 in patients with advanced MET-altered solid tumors, including non-small cell lung cancer and gastric cancer; the t…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Study on the Mechanism of Acquired Resistance of Entrectinib
A clinical trial update from Fudan University studying how resistance to entrectinib develops in ROS1 fusion-positive non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer [NA]
Clinical trial update for NutriCare Plus, a medically tailored meal intervention, being studied in patients with various forms of lung cance…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Sequential Chemotherapy With Befotertinib in Non-Small Cell Lung Cancer (NSCLC) Patients With Resistance to Third-Generation EGFR-TKI [Phase 2]
Phase 2 clinical trial update evaluating sequential chemotherapy with befotertinib in non-small cell lung cancer patients who have developed…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Effects of Essential Amino Acid Intake on Net Protein Synthesis in Weight-losing Non-small Cell Lung Cancer Patients [NA]
A completed clinical trial studied the effects of essential amino acid intake on net protein synthesis in weight-losing patients with non-sm…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: 18FDG PET for Early Identification of Tumor Exhaust for Immunotherapy in Patients With Locally Advanced or Metastatic Non-Small Cell Bronchopulmonary Carcinoma or Melanoma [NA]
A completed clinical trial evaluating 18F-FDG PET imaging to identify tumor exhaustion early to guide immunotherapy in patients with locally…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies [Phase 1]
Phase Ib study of TNO155 in combination with Spartalizumab or Ribociclib in selected malignancies was terminated, involving multiple indicat…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: IBI363 Combined With Chemotherapy or Pembrolizumab Combined With Chemotherapy as Neoadjuvant Therapy in Resectable Stage IB-III Non-Squamous Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating neoadjuvant therapy for resectable stage IB-III non-squamous non-small cell lung cancer, comparing IBI-3…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: A Real-World Study of IBI351 for KRAS G12C+ NSCLC in China
A real-world study of IBI351 for KRAS G12C-positive non-small cell lung cancer in China, with the trial status listed as not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Real World Study of Platinum Containing Dual Drug Chemotherapy Followed by Large Fractionated Radiotherapy Combined withTislelizumab in Stage IIIB/C-IV Non-small Cell Lung Cancer Patient [Phase 2]
Phase 2 real-world study evaluating platinum-containing dual-drug chemotherapy followed by large-fractionated radiotherapy in combination wi…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: A Single-Arm, Open-Label, Multicenter Phase I/II Clinical Study of GFH276 in Patients With RAS-Mutant Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a single-arm, open-label Phase I/II study of GFH276 in patients with RAS-mutant advanced solid tumors, …
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Real-world Study of Taletrectinib in Advanced ROS1+ NSCLC Following Entrectinib Progression
Real-world study assessing taletrectinib in advanced ROS1-positive non-small cell lung cancer after progression on entrectinib; the trial st…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Clinical Efficacy and Safety of Microwave Ablation Combined With Huaier Granules in Patients With Inoperable Stage IA Non-Small Cell Lung Cancer: A Prospective, Single-Center, Randomized Controlled Clinical Trial [Phase 3]
A Phase 3 randomized trial protocol evaluating the efficacy and safety of combining microwave ablation with Huaier Granules in patients with…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Sacituzumab Tirumotecan (Sac-TMT) Plus Bevacizumab in 3rd Generation EGFR-TKI Treated Advanced EGFR-mutant Nonsquamous NSCLC With Brain Metastasis [Phase 2]
This Phase 2 trial evaluates sacituzumab tirumotecan plus bevacizumab in advanced EGFR-mutant nonsquamous non-small cell lung cancer with br…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer [NA]
A recruiting clinical trial evaluating adding pemetrexed to a third-generation EGFR tyrosine kinase inhibitor (e.g., osimertinib) versus the…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer) [Phase 2]
Phase 2 single-arm trial evaluating the combination of Datopotamab Deruxtecan, carboplatin, and pembrolizumab for treatment-naive brain meta…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer or Other Solid Tumors [Phase 1, Phase 2]
BL-M02D1 is undergoing a Phase 1/2 study in locally advanced or metastatic non-small cell lung cancer and other solid tumors. The sponsor is…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: SI-B001 Combined With Osimertinib Mesylate Tablets in the Treatment of Recurrent Metastatic Non-small Cell Lung Cancer. [Phase 2, Phase 3]
An update on a Phase 2/Phase 3 clinical trial evaluating SI-B001 in combination with Osimertinib for recurrent metastatic non-small cell lun…
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: A Study of ES102 in Combination With Toripalimab in Subjects With Advanced Non-small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating ES102 in combination with toripalimab for advanced non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: Calypso-based Deep Inspiration Breath Hold (DIBH) Radiation Treatments of Lung Cancer [NA]
This clinical trial update reports the completion and results posting for Calypso-based deep inspiration breath hold radiation therapy in pa…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer [Phase 2]
A Phase 2 trial evaluating Olvimulogene Nanivacirepvec with platinum-doublet chemotherapy and physician-chosen immune checkpoint inhibitor v…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors [Phase 2]
Phase 2 clinical trial update for SI-B003 and the BL-B01D1+SI-B003 combination in locally advanced or metastatic non-small cell lung cancer,…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Efficacy Comparison of Cobolimab + Dostarlimab + Docetaxel to Dostarlimab + Docetaxel to Docetaxel Alone in Participants With Advanced Non-small Cell Lung Cancer Who Have Progressed on Prior Anti-PD-(L)1 Therapy and Chemotherapy [Phase 3]
Phase 3 clinical trial update evaluating cobolimab + dostarlimab + docetaxel versus dostarlimab + docetaxel and docetaxel alone in advanced …