Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Quality of Life Intervention to Inform Patient Decision-Making in Early-Stage Lung Cancer [NA]
This clinical trial investigates a quality-of-life intervention to help patients with early-stage non-small cell lung cancer make informed t…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: A Study of HMBD-002, a Monoclonal Antibody Targeting VISTA, as Monotherapy and Combined With Pembrolizumab, in Patients With Advanced Solid Tumors [Phase 1]
This is a completed Phase 1 trial of HMBD-002, a VISTA-targeting monoclonal antibody, as monotherapy and with pembrolizumab in patients with…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation [Phase 1]
Phase 1 trial evaluating PRT3789 as monotherapy or in combination with docetaxel in SMARCA4-mutant advanced/metastatic solid tumors has comp…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Study of the Monoclonal Antibody IMT-009 in Patients With Advanced Solid Tumors or Lymphomas [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/2 study of the monoclonal antibody IMT-009 in various advanced solid tumors and lymphomas, with t…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Osimertinib Plus Chemotherapy in Uncommon EGFRm NSCLC [Phase 2]
A Phase 2 trial evaluating osimertinib in combination with chemotherapy for uncommon EGFR-mutant non-small cell lung cancer has been termina…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors [Phase 1]
A Phase 1 clinical trial evaluating genetically engineered natural killer (NK) cells with or without atezolizumab for non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
An observational clinical trial from OncoHost Ltd. aims to predict responsiveness to anti-cancer treatments in patients with advanced cancer…
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CLINICAL_TRIALS other · 2025-10-15Clinical Trial Update: Osimertinib Monotherapy or Combination With Chemotherapy for Advanced NSCLC Concurrent EGFR and TP53 Mutations [Phase 3]
Phase 3 trial update evaluating osimertinib alone or with chemotherapy in advanced non-small cell lung cancer with concurrent EGFR and TP53 …
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Phase II Clinical Trial of NIVO-IPI-TAXANE in Untreated Metastatic NSCLC [Phase 2]
Phase II results have been posted for a nivolumab-ipilimumab-taxane regimen in untreated metastatic non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: eXalt3: Study Comparing X-396 (Ensartinib) to Crizotinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) Patients [Phase 3]
Update on the Phase 3 eXalt3 trial comparing Ensartinib (X-396) to Crizotinib in ALK-positive non-small cell lung cancer, with the study cur…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: Long-Term Safety Outcomes and First-Line Treatment Patterns in Patients With Non-Small Cell Lung Cancer and Programmed Death-1 (Pd-L1) <1%
Clinical trial update describing long-term safety outcomes and initial first-line treatment patterns in patients with non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer [Phase 1]
A Phase 1 study evaluating TAS2940 in locally advanced or metastatic solid tumors has been terminated. The trial enrolled patients with glio…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies [Phase 1]
A Phase 1 study of JANX008 in advanced or metastatic solid tumors is currently recruiting, evaluating multiple indications including Non-Sma…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: MOv19-BBz CAR T Cells in FRa+ Cancers [Phase 1]
Phase 1 trial evaluating MOv19-BBz CAR T cells targeting FRα in metastatic or recurrent non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study evaluating OP-3136 in advanced or metastatic solid tumors, including ER-positive/HER2-negative breast cancer, non-small cell l…
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FDA approval · 2025-10-09FDA Approved: PEMETREXED — Supplemental Application (Waverley Pharma Inc)
FDA approved a supplemental application for pemetrexed disodium by Waverley Pharma Inc, resulting in updated approval/label for the generic …
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation. [Phase 2]
This is a Phase 2 clinical trial evaluating JDQ443 as a single-agent first-line therapy for locally advanced or metastatic KRAS G12C-mutated…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations [Phase 1, Phase 2]
This clinical trial investigates whether adding valemetostat tosylate to pembrolizumab improves outcomes compared with pembrolizumab alone i…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of radiation therapy with a DLL3-targeting bispecific T-cell engager in DLL3-expres…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer [Phase 1, Phase 2]
Update on a Phase 1/2 trial evaluating pembrolizumab with stereotactic body radiation therapy or wide-field radiation therapy in patients wi…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: Evaluating the Feasibility and Preliminary Effects of BE+ [NA]
A clinical trial update on BE+ evaluating feasibility and preliminary effects in non-small cell lung cancer, focusing on self-management beh…
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CLINICAL_TRIALS research · 2025-10-09Clinical Trial Update: A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer [Phase 1, Phase 2]
Clinical trial update on AZD7789 evaluating safety and efficacy in participants with advanced or metastatic solid cancers in Phase 1/2.
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Stereotactic Body Radiation Therapy Planning With Artificial Intelligence-Directed Dose Recommendation for Treatment of Primary or Metastatic Lung Tumors, RAD-AI Study [NA]
The RAD-AI study seeks to use artificial intelligence-directed dose planning for stereotactic body radiation therapy in patients with primar…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of intratumoral MVR-T3011 given alone or with pembrolizumab in adults with advanced o…
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CLINICAL_TRIALS research · 2025-10-08Clinical Trial Update: Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
This clinical trial update describes a study evaluating detection of tumor cells and tumor DNA in blood, urine, and bone marrow across multi…