Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene [Phase 1, Phase 2]
A Phase 1/2 study of bemcentinib combined with standard chemoimmunotherapy in untreated advanced/metastatic non-small cell lung cancer with …
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab [Phase 1]
A Phase 1 clinical trial update shows ABBV-400 alone or with bevacizumab being studied in adults with advanced solid tumors, including non-s…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Biology of Young Lung Cancer Study: The YOUNG LUNG Study
The YOUNG LUNG Study is currently recruiting, focusing on the biology of lung cancer in younger patients.
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: Anti-PD-L1 in Stage IIIA(N2) Non-small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial of an anti-PD-L1 therapy in stage IIIA(N2) non-small cell lung cancer has completed with results posted.
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: LUNAR-4: Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Pembrolizumab for Treatment of Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating Tumor Treating Fields (TTFields) at 150 kHz in combination with pembrolizumab for metastatic non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
Clinical trial SYNERGY-AI is an AI-based precision oncology matching and registry study sponsored by Massive Bio, currently recruiting acros…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Atezolizumab and Stereotactic Body Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer [Phase 1]
This Phase 1 clinical trial update evaluates atezolizumab in combination with stereotactic body radiation therapy for Stage I non-small cell…
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy [Phase 2]
Phase II umbrella study evaluating multiple novel anti-cancer agents in non-small cell lung cancer patients who progressed on anti-PD-1/PD-L…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy [Phase 1]
A Phase 1 trial evaluating NBTXR3 activated by radiotherapy in combination with anti-PD-1 therapy for patients with advanced cancers; the st…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs [Phase 1, Phase 2]
Krystal Biotech's KB707 is being evaluated in a Phase 1/2 study for advanced solid tumors affecting the lungs, including non-small cell and …
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1) [Phase 1, Phase 2]
Phase 1/2 study assessing Zidesamtinib (NVL-520) in patients with ROS1-rearranged non-small cell lung cancer and other ROS1-rearranged solid…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial of Telisotuzumab vedotin in adults with advanced/metastatic non-squamous non-small cell lung cancer was terminated, with res…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Korea Osimertinib Real World Evidence Study to Assess Safety and Efficacy - PLUS
A completed real-world evidence study in Korea assessed the safety and efficacy of osimertinib for non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement [Phase 1]
A first-in-human Phase 1 trial of PF-07284890 in patients with BRAF V600 mutant solid tumors, including those with brain involvement, has be…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475 [Phase 2]
Phase 2 trial evaluating the combination of recombinant EphB4-HSA fusion protein with pembrolizumab has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line Treatment [Phase 2]
Clinical trial update on a Phase 2 study of sotorasib (Lumakras) for first-line treatment of stage IV KRAS p.G12C-mutant non-small cell lung…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
This document notes an ongoing Phase 1/2 clinical trial by BioNTech evaluating the safety and potential benefit of the investigational combi…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
The ALLUME Study is evaluating microwave ablation versus wedge resection for treatment of lung, sarcoma, and colorectal lesions, including v…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01) [Phase 1]
First-in-human Phase 1 study of DS-1062a for advanced solid tumors, including breast cancer subtypes and non-small cell lung cancer, is unde…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer [Phase 1, Phase 2]
This is a Phase 1/Phase 2 clinical trial evaluating the immune response to a MUC1 peptide vaccine in patients with non-small cell lung cance…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Premedication to Reduce Amivantamab Associated Infusion Related Reactions [Phase 2]
Phase 2 trial update examining premedication to reduce infusion-related reactions with amivantamab in non-small cell lung cancer; results ha…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Study of PULSAR-ICI +/- IMSA101 in Patients With Oligometastatic NSCLC and RCC [Phase 2]
A Phase 2 study of PULSAR-ICI with or without IMSA101 in patients with oligometastatic non-small cell lung cancer and renal cell carcinoma w…
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: A First-in-human Study to Learn How Safe the Study Treatment BAY2862789 is, to Find the Best Dose, How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, and How it Acts on Different Tumors in Participants With Advanced Solid Tumors [Phase 1]
This first-in-human Phase 1 study of BAY2862789 aims to assess safety, determine the recommended dose, characterize pharmacokinetics/pharmac…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation [Phase 2]
A Phase II neoadjuvant trial is evaluating sotorasib in combination with cisplatin or carboplatin and pemetrexed for surgically resectable s…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Gilteritinib for the Treatment of ALK NSCLC [Phase 1]
A Phase 1 trial evaluating gilteritinib for ALK-positive non-small cell lung cancer is currently recruiting.