Non-small Cell Lung Cancer
📧 Sign up to get email alerts when something new happens for Non-small Cell Lung Cancer.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity Between SB27 and Keytruda in Subjects With Metastatic Non-squamous Non-small Cell Lung Cancer [Phase 3]
This Phase 3 trial compares SB27, a pembrolizumab biosimilar, with Keytruda (pembrolizumab) in patients with metastatic non-squamous non-sma…
-
CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study of YL201 and Ivonescimab (AK112) in Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating YL201 in combination with Ivonescimab (AK112) for advanced solid tumors, including non-small cell lung…
-
CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer or Pulmonary Oligometastases [Phase 2]
Phase 2 trial evaluating whether online adaptive stereotactic radiotherapy can eliminate planning target volume (PTV) margins in early-stage…
-
CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Elimination of PTV Margins Based on MRI-guided Adaptive Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Brain Metastasis [Phase 2]
Phase 2 clinical trial investigating MRI-guided adaptive stereotactic radiotherapy to eliminate planning target volume margins in non-small …
-
CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: The Impact of Thymosin α-1 on the Efficacy of Concurrent Chemoradiotherapy Followed by Immunotherpay Consolidation for Locally Advanced NSCLC [Phase 2]
Phase 2 trial investigating whether Thymosin α-1 enhances the efficacy of concurrent chemoradiotherapy followed by immunotherapy consolidati…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer [Phase 3]
Phase III open-label trial evaluating first-line osimertinib with or without datopotamab deruxtecan for EGFR-mutant locally advanced or meta…
-
CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies [Phase 1, Phase 2]
Clinical trial update for BT8009-100 in nectin-4 expressing advanced malignancies (Phase 1/2) with status ACTIVE_NOT_RECRUITING.
-
CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Impact of Smoking Cessation Duration on Postoperative Complications in Lung Cancer Surgery
This clinical trial evaluates whether longer duration of smoking cessation before lung cancer surgery reduces postoperative complications in…
-
CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Study of Pembrolizumab/Vibostolimab Coformulation (MK-7684A) in Combination With Chemotherapy Versus Pembrolizumab Plus Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (MK-7684A-007/KEYVIBE-007) [Phase 3]
Phase 3 trial MK-7684A-007/KEYVIBE-007 comparing pembrolizumab/vibostolimab coformulation plus chemotherapy to pembrolizumab plus chemothera…
-
CLINICAL_TRIALS trial_result · 2025-11-13Clinical Trial Update: Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer [Phase 1]
This Phase 1 trial evaluates the safety, pharmacokinetics, and activity of GDC-1971 in combination with osimertinib for unresectable, locall…
-
CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Osimertinib and Gefitinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating the EGFR inhibitors osimertinib and gefitinib in EGFR-inhibitor naïve patients with advanced EG…
-
CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Nivolumab in Combination With Plinabulin in Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 1]
Phase 1 trial of nivolumab in combination with plinabulin for metastatic non-small cell lung cancer has completed.
-
CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: A Study of Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77)-Japan Extension [Phase 3]
Phase 3 trial update comparing subcutaneous pembrolizumab coformulated with berahyaluronidase alfa (MK-3475A) to intravenous pembrolizumab i…
-
CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS [Phase 1, Phase 2]
A Phase 1/Phase 2 study evaluating RMC-6236 in patients with advanced solid tumors harboring RAS mutations, including non-small cell lung ca…
-
CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC [Phase 2]
A Phase 2 study evaluating EIK1001 in combination with pembrolizumab and chemotherapy for Stage 4 non-small cell lung cancer is currently re…
-
EMA withdrawal · 2025-11-11EMA Application withdrawn: Datopotamab deruxtecan Daiichi Sankyo (datopotamab deruxtecan) — Daiichi Sankyo Europe GmbH
EMA has withdrawn the marketing authorization application for datopotamab deruxtecan by Daiichi Sankyo Europe GmbH for non-small cell lung c…
-
CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors [Phase 1, Phase 2]
Phase I/II trial of autologous T cells engineered to express T-cell receptors (TCRs) in patients with solid tumors was terminated with resul…
-
CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: TG4010 and Nivolumab in Patients With Lung Cancer [Phase 2]
Phase 2 trial update reporting completion of a study evaluating TG4010 in combination with nivolumab for non-small cell lung cancer, with re…
-
CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: A Study to Test Different Doses of BI 836880 Combined With Ezabenlimab in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours [Phase 1]
Phase 1 trial evaluating different doses of BI 836880 in combination with Ezabenlimab in patients with advanced non-small cell lung cancer; …
-
CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors [Phase 1]
This is a completed Phase 1 clinical trial update evaluating CHS-388 (formerly SRF388) in patients with advanced solid tumors, including cle…
-
CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: A Pilot Study of Blood-based Biomarkers for Response to Immune Checkpoint Inhibitors
A pilot clinical trial update evaluating blood-based biomarkers to predict response to immune checkpoint inhibitors in non-small cell lung c…
-
CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating a recombinant EphB4-HSA fusion protein in combination with standard chemotherapy for advanced or metastatic solid t…
-
CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating nivolumab with radiation therapy, with or without ipilimumab, for brain metastases arising from non-smal…
-
CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial update evaluating CIMAvax-EGF vaccine in combination with nivolumab and pembrolizumab for advanced or metasta…
-
CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer [Phase 2]
This entry describes a Phase 2 clinical trial evaluating proton beam radiation therapy after surgical resection for N2 non-small cell lung c…