Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Combination of Paclitaxel-bevacizumab ± Atezolizumab in Patients With Advanced NSCLC Progressing After Immunotherapy & Chemotherapy [Phase 2]
This is a Phase 2 clinical trial evaluating paclitaxel with bevacizumab, with or without atezolizumab, in patients with advanced non-small c…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Study of QL1706 in Combination With Chemotherapy in PD-L1-Negative Non-small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial evaluating QL1706 in combination with chemotherapy for patients with PD-L1-negative non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Early Specialized Cardiovascular Intervention Based on Impedance Cardiography in Locally Advanced Non-small Cell Lung Cancer Patients [Phase 3]
Phase 3 clinical trial evaluating early specialized cardiovascular intervention guided by impedance cardiography in locally advanced non-sma…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: A Study of Tolododekin Alfa (ANK-101) in Combination With an Anti-PD-1/PD-L1 Antibody in Participants With Advanced Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 study of Tolododekin Alfa (ANK-101) in combination with an anti-PD-1/PD-L1 antibody in adults with advanced non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Lung Cancer With Copanlisib and Durvalumab [Phase 1]
Phase 1 trial update on the combination of copanlisib and durvalumab for non-small cell lung cancer has completed its Phase 1 portion.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Phase II Clinical Study of SHR2554 Tablets Combined With Other Anti-tumor Treatments in Non-small Cell Lung Cancer Subjects [Phase 2]
Phase II clinical trial of SHR2554 tablets in combination with other anti-tumor treatments for locally advanced or metastatic non-small cell…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer [Phase 1]
Phase 1 trial of DS8201a (trastuzumab deruxtecan) in combination with pembrolizumab for locally advanced/metastatic breast cancer or non-sma…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: ENCOrafenib With Binimetinib in bRAF NSCLC [Phase 2]
Phase 2 trial evaluating encorafenib plus binimetinib in non-small cell lung cancer with BRAF V600E mutation; current status is active but n…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Physical Activity Coaching After Surgery for Patients With Resectable Non-small Cell Lung Cancer [NA]
This clinical trial update notes that a study examining physical activity coaching after surgery for patients with resectable non-small cell…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy [Phase 3]
Phase 3 trial evaluating atezolizumab with carboplatin/paclitaxel in elderly patients with advanced non-small cell lung cancer; the study is…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Atezolizumab Plus 8 Gy Single-fraction Radiotherapy for Advanced Oligoprogressive NSCLC [Phase 2]
Phase 2 trial evaluating atezolizumab in combination with 8 Gy single-fraction radiotherapy for advanced oligoprogressive non-small cell lun…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TNG260 in combination with an anti-PD antibody in STK11-mutated solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Feasibility Testing of a Dyadic Exercise Program for Patients Undergoing Thoracic Radiotherapy and Their Family Caregivers [NA]
A clinical trial is evaluating the feasibility of a dyadic exercise program for patients undergoing thoracic radiotherapy and their family c…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 randomized study comparing docetaxel alone versus docetaxel with bintrafusp alfa in advanced non-small cell lung cancer was termin…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors [Phase 2]
Phase 2 study evaluating SOT101 in combination with pembrolizumab in selected advanced solid tumors was terminated; results have been posted…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC（SYNSTAR01） [Phase 3]
This document provides an update on a Phase 3 clinical trial (SYNSTAR01) evaluating SYS6010 versus platinum-based chemotherapy in EGFR-mutat…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study to Compare the Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Pembrolizumab (SB27, EU Sourced Keytruda, and US Sourced Keytruda) in Subjects With Stage II-IIIA NSCLC Following Complete Resection and Adjuvant Platinum-based Chemotherapy [Phase 1]
Phase 1 trial comparing pharmacokinetics, efficacy, safety, and immunogenicity of the pembrolizumab biosimilar SB27 versus EU/US-sourced pem…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Afuresertib +Sintilimab+Chemotherapy in Patients With Selected Solid Tumors That Resistance to Prior Anti-PD-1/PD-L1 [Phase 1, Phase 2]
A phase 1/2 trial evaluating afuresertib in combination with sintilimab and chemotherapy in selected solid tumors resistant to prior PD-1/PD…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Study of Safety and Efficacy of Brigatinib Plus Chemotherapy or Brigatinib Only in Advanced ALK-Positive Lung Cancer (MASTERPROTOCOL ALK) [Phase 2]
Clinical trial update for MASTERPROTOCOL ALK (NCT05200481) evaluating brigatinib with or without chemotherapy in advanced ALK-positive non-s…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies [Phase 1]
This clinical trial update notes the termination of a Phase 1 study of BDC-3042 as a single agent and in combination with cemiplimab in pati…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors [Phase 1, Phase 2]
Phase Ib/II clinical study evaluating HLX43 in combination with serplulimab for advanced/metastatic solid tumors is currently recruiting. Th…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Dose-escalation and Dose-expansion Phase I/Phase II Clinical Study of Dositinib Mesylate Tablets (90-1408) in the Treatment of Locally Advanced or Metastatic Non-small Cell Lung Cancer With Positive EGFR Mutation [Phase 1, Phase 2]
A dose-escalation and dose-expansion Phase I/II clinical study of Dositinib Mesylate Tablets for locally advanced or metastatic non-small ce…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression [Phase 1, Phase 2]
Clinical trial update for BT5528-100 (Phase 1/2) in EphA2-expressing advanced solid tumors. The study includes urothelial carcinoma, ovarian…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study of BL-M07D1 vs Pembrolizumab-platinum Chemotherapy in First-line Treatment of HER2-mutant Advanced or Metastatic Non-squamous NSCLC [Phase 3]
Phase 3 trial evaluating BL-M07D1 versus pembrolizumab plus platinum-based chemotherapy as first-line treatment for HER2-mutant advanced or …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
This is a screening study by TScan Therapeutics to collect samples for tumor-associated antigens, HLA typing, and HLA loss of heterozygosity…