Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial) [Phase 2]
Phase 2 expanded Lung-MAP trial evaluating a MET-targeted therapy for advanced non-small cell lung cancer with MET gene amplification; recru…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer [Phase 2, Phase 3]
Lung-MAP is a master screening protocol for patients with previously treated non-small cell lung cancer, currently in Phase 2 and Phase 3 an…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Atezolizumab Plus Bevacizumab in First Line NSCLC Patients [Phase 2]
This update reports results from a Phase 2 trial evaluating the combination of Atezolizumab and Bevacizumab as first-line therapy for Non-Sm…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Predictive Value of Exosomes in Pleural Effusion for Advanced Lung Cancer
This clinical trial update investigates whether exosomes from pleural effusion can serve as predictive biomarkers for outcomes in advanced n…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Neoadjuvant Chemo-immunotherapy for Stage III PD-L1 Positive Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial update announcing ongoing recruitment for neoadjuvant chemo-immunotherapy in stage III PD-L1 positive non-small cell lung ca…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer [Phase 1, Phase 2]
Takeda's TAK-186 (MVC-101) was studied in a Phase 1/2 trial for adults with advanced or metastatic cancers including squamous cell carcinoma…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: SX-682 With Pembrolizumab for the Treatment of Metastatic or Recurrent Stage IIIC or IV Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial is evaluating SX-682 in combination with pembrolizumab for metastatic or recurrent stage IIIC or IV non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Early Assessment of Response to Treatment of Metastatic LUng Tumors Based on CIrculating Tumor DNA [NA]
A completed clinical trial update evaluating early response to treatment in metastatic non-small cell lung cancer using circulating tumor DN…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: A Randomized Phase II Trial of Cemiplimab Plus OSE2101 ( TEDOPI®) as Maintenance Therapy in ctDNA Positive NSCL. The Cemited Study. [Phase 2]
A Phase II randomized trial is evaluating cemiplimab plus OSE2101 (TEDOPI) as maintenance therapy in ctDNA-positive non-small cell lung canc…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Patient and Physician Preference Study in Resectable, Non-small Cell Lung Cancer Treatments
This Bristol-Myers Squibb sponsored study focuses on patient and physician preferences for treatments in resectable non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Assessing an Oral EGFR Inhibitor, Sunvozertinib in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR or HER2 Mutation (WU-KONG1) [Phase 1, Phase 2]
A Phase 1/2 clinical trial update on sunvozertinib, an oral EGFR inhibitor, in adults with advanced non-small cell lung cancer harboring EGF…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Influence of a PSychological Intensive Support Program for Lung Cancer Patients ON Post-operative Outcomes. [NA]
This entry describes a clinical trial evaluating the effect of a Psychological Intensive Support Program on postoperative outcomes in non-sm…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Residual Disease Evaluation of Resected NSCLC by cirDNA Analysis [NA]
This ClinicalTrials.gov update describes a study evaluating residual disease in resected non-small cell lung cancer using circulating tumor …
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Study of GV20-0251 in Participants With Solid Tumor Malignancies [Phase 1, Phase 2]
GV20 Therapeutics is evaluating GV20-0251 in a Phase 1/2 trial for adults with various solid tumors, and the study is currently recruiting. …
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EMA approval · 2025-12-02EMA Authorised: Krazati (adagrasib) — Bristol-Myers Squibb Pharma EEIG
The European Medicines Agency authorised Krazati (adagrasib) for non-small cell lung cancer under conditional approval.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Palliative RadIotherapy of Multiple Metastatic Sites Before First Line of Systemic Therapy With Immune Checkpoint Inhibitors and Chemotherapy in Metastatic Non-Small-Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluating palliative radiotherapy to multiple metastatic sites before first-line systemic therapy with immune checkpoint in…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Optimal Methods to Characterize ADC Resistance in Solid Tumors and Identify Clinically Useful Biomarkers [Phase 2]
Phase 2 clinical trial focusing on methods to characterize resistance to antibody-drug conjugates in solid tumors and to identify clinically…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Application Research of Methylation Markers in Early-stage Lung Cancer Patients Treated With Co-ablation System Therapy
This clinical trial investigates methylation markers for early-stage non-small cell lung cancer in patients treated with the Co-ablation Sys…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Phase II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Subjects With Advanced Lung Cancer [Phase 2]
Phase II clinical study to evaluate HLX43 in combination with Serplulimab for advanced lung cancer; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Phase II Clinical Study of Pyrotinib in First-line Treatment of Primary HER2-amplified/Mutated Advanced Non-small Cell Lung Cancer [Phase 2]
Phase II study of Pyrotinib as first-line therapy for HER2-amplified/mutated advanced non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Real-Time Non-Invasive Localization for Multiple Lung Nodules [NA]
The document notes the completion of a clinical trial investigating real-time non-invasive localization for multiple lung nodules in non-sma…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: A Study to Evaluate PK, Efficacy, and Safety of BAT3306 Plus Chemo and Compare With Keytruda®(EU/US) in Participants With IV nqNSCLC [Phase 3]
A Phase 3 trial evaluating BAT3306 plus chemotherapy versus Keytruda (pembrolizumab) in non-small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: RAPART in Locally Advanced Non-small Cell Lung Cancer Patients [NA]
RAPART trial in locally advanced non-small cell lung cancer is currently recruiting at Capital Medical University.
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Application of Methylation Markers in Early Detection and MRD Monitoring of Lung Cancer
This clinical trial evaluates methylation markers for early detection and minimal residual disease monitoring in non-small cell lung cancer.