Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Hyperprogression in PD-L1 ≥ 50% NSCLC: a Biomarker Guided Phase 2 Trial [Phase 2]
A biomarker-guided Phase 2 trial in non-small cell lung cancer evaluating hyperprogression in patients with PD-L1 expression ≥ 50%. The stud…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: MAGE A10ᶜ⁷⁹⁶T for Advanced NSCLC [Phase 1]
A Phase 1 trial of Adaptimmune's MAGE-A10 796T T-cell receptor therapy for advanced non-small cell lung cancer has completed the Phase 1 sta…
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: An Autologous NK/CIK Cell Product (PB101) in Combination With EGFR-TKI for Treating Lung Cancer [Phase 1]
Phase 1 trial update of PB101, an autologous NK/CIK cell product, in combination with an EGFR-TKI, for non-small cell lung cancer; the study…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations [Phase 1, Phase 2]
Phase 1/2 study of Silevertinib (BDTX-1535) in glioblastoma and EGFR-mutant non-small cell lung cancer is currently active but not recruitin…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: A Phase 2 Randomized, Controlled Trial of QL1706 Plus Chemotherapy and Quad Shot for Driver Gene-negative Advanced Non-small Cell Lung Cancer. [Phase 2]
Phase 2 randomized trial assessing QL1706 plus chemotherapy and Quad Shot for driver gene-negative advanced non-small cell lung cancer; the …
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: Evaluation of Efficacy of Minimally Invasive Local Therapy for Lung Tumors and Its Impact on Breathing Function [NA]
Clinical trial update on evaluating the efficacy of minimally invasive local therapy for lung tumors and its impact on breathing function.
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Impact of Circadian Rhythm on Immunotherapy [Phase 2]
Phase 2 trial evaluating the impact of circadian rhythm on immunotherapy in advanced/metastatic non-small cell lung cancer; currently recrui…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Osimertinib and Tegavivint as First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial evaluating first-line combination therapy with osimertinib and tegavivint for metastatic EGFR-mutant non-small cell…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: This Study is Comparing Morning vs Random Scheduling of Standard of Care Pembrolizumab Checkpoint Inhibitor Immunotherapy Infusions in Patients With Metastatic Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial comparing morning versus random scheduling of standard-of-care pembrolizumab infusions for metastatic non-small cel…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating photon craniospinal irradiation for leptomeningeal metastases arising from breast cancer or non-small ce…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Shared Decision Making on Radiation Dose for Lung Malignancies [NA]
Clinical trial update indicates ongoing recruitment for a study on shared decision making regarding radiation dose in lung cancer patients, …
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) [Phase 2]
Phase 2 trial update for sotorasib (AMG 510) in KRAS G12C-mutated advanced non-squamous non-small cell lung cancer, highlighting ongoing stu…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Cancer Therapy-Related Cardiac Dysfunction Associated With EGFR-TKIs in Advanced EGFR-mutant Non-small Cell Lung Cancer
A completed clinical trial update investigates cancer therapy-related cardiac dysfunction associated with EGFR-TKIs in advanced EGFR-mutant …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Phase III Study of SKB264 for EGFR Mutant NSCLC Patients [Phase 3]
This is an update on a Phase III trial evaluating SKB264 in EGFR-mutant non-small cell lung cancer; the study is currently active but not re…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Study of SYS6010 Combined With Osimertinib Versus Osimertinib Alone as Neoadjuvant Therapy for Patients With EGFR Mutation-positive Resectable Non-squamous Non-small Cell Lung Cancer [Phase 2]
This clinical trial update describes a Phase 2 neoadjuvant study evaluating SYS6010 plus osimertinib versus osimertinib alone in EGFR-mutant…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer [Phase 2]
A Phase 2 trial evaluating Vidutolimod in combination with cemiplimab for adults with advanced or metastatic cancers was terminated, with re…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC [Phase 1]
Phase 1 study evaluating the safety and feasibility of combining pirfenidone with standard first-line chemotherapy in advanced non-small cel…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Staggered, Chemo-Immunotherapy With Durvalumab, MEDI4736 Pemetrexed & Carboplatin (PC) for Metastatic Non-Squamous NSCLC [Phase 2]
Phase 2 trial evaluating staggered durvalumab with pemetrexed and carboplatin for metastatic non-squamous non-small cell lung cancer; the st…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion [Phase 1]
Bristol-Myers Squibb is conducting a Phase 1 trial of MRTX1719 in MTAP-deleted solid tumors, including mesothelioma, non-small cell lung can…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Minimal Residual Disease in Solid Malignancies [NA]
This clinical trial update describes a study evaluating minimal residual disease in solid malignancies across several cancers, and it is cur…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial) [Phase 2]
A Phase 2 SWOG Lung-MAP trial is evaluating combinations of targeted therapies for advanced non-small cell lung cancer with EGFR and MET gen…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Exercise as a Tool to Improve Response to Immunotherapy in Non-small Cell Lung Cancer [NA]
This clinical trial aims to assess whether exercise can improve responses to immunotherapy in non-small cell lung cancer, with the study cur…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Smartphone-based Remote Symptom Monitoring to Improve Postoperative Rehabilitation Exercise Adherence After Video-assisted Thoracic Surgery (VATS) for Lung Cancer [NA]
This clinical trial investigates smartphone-based remote symptom monitoring to improve adherence to postoperative rehabilitation exercises a…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: A Study of SKB264 in Combination With Osimertinib Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Mutations, Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating SKB264 in combination with Osimertinib versus Osimertinib alone in EGFR-mutant non-squamous non-small cell lung can…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Study of Binimetinib in Combination With Pembrolizumab in Advanced Non-Small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating the combination of binimetinib and pembrolizumab for advanced non-small cell lung cancer, currently recruiting.