Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Osimertinib Plus Capivasertib in NSCLC With PIK3CA/AKT1/PTEN Alterations Following Prior 1L Osimertinib [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of osimertinib and capivasertib in patients with advanced non-small cell lung cancer h…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy [Phase 1]
This is a Phase I trial evaluating atezolizumab with interleukin-12 gene therapy in metastatic non-small cell lung cancer that progressed af…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer [Phase 1]
Phase 1 study evaluating the efficacy and safety of Cofetuzumab Pelidotin in PTK7-expressing, recurrent non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: SHR-A1811 + AK112 in HER2-Altered Advanced/Metastatic NSCLC [Phase 2]
This document details a Phase 2 clinical trial of SHR-A1811 plus AK112 in HER2-altered advanced/metastatic non-small cell lung cancer, which…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC [Phase 1, Phase 2]
Clinical trial update for AZD2936, a bispecific anti-TIGIT/anti-PD-1 antibody, in participants with advanced or metastatic non-small cell lu…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Phase II Clinical Trial of SHR-1826 for Non-Small Cell Lung Cancer [Phase 2]
Phase II clinical trial update for SHR-1826 in non-small cell lung cancer; the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Intrathecal Pemetrexed for Leptomeningeal Metastasis in EGFR-Mutant NSCLC [Phase 2]
A Phase 2 clinical trial evaluating intrathecal pemetrexed for leptomeningeal metastasis in EGFR-mutant non-small cell lung cancer is curren…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Phase III Study of AK112 for NSCLC Patients [Phase 3]
This document provides an update on a Phase III trial of AK112 for non-small cell lung cancer. The study is currently active but not recruit…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Family-Supported Palliative Care in Advanced Lung Cancer [NA]
This clinical trial evaluated family-supported palliative care in advanced lung cancer, including non-small cell lung cancer, and has comple…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC [Phase 3]
A Phase 3 trial of neladalkib (NVL-655) for tyrosine kinase inhibitor–naive patients with advanced ALK-positive non-small cell lung cancer i…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Photoimmunotherapy With ASP-1929 and Cemiplimab for the Treatment of Refractory, Inoperable, and Metastatic Stage IIIB-IV Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating ASP-1929 photoimmunotherapy in combination with cemiplimab for refractory, inoperable, and metastatic non-small cel…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating a T cell receptor–based immunotherapy for patients with metastatic non-small cell lung cancer is current…
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CLINICAL_TRIALS other · 2026-03-24Clinical Trial Update: Concomitant Use of Radiotherapy and Integrated Exercise - Lung Cancer [NA]
Administrative update on a clinical trial evaluating concomitant radiotherapy and integrated exercise for non-small cell lung cancer. The st…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4 [Phase 1]
Phase 1/1b trial evaluating RNDO-564 as a single agent or in combination with pembrolizumab in bladder cancer and nectin-4–associated solid …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer [Phase 3]
Clinical trial update for a Phase 3 study of nivolumab and ipilimumab with or without local consolidation therapy in patients with Stage IV …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Study of Healthy Donor FMT (hdFMT) and Pembrolizumab in Relapsed/Refractory (R/R) PD-L1 Positive NSCLC [Phase 2]
Phase 2 trial evaluating healthy donor fecal microbiota transplant in combination with pembrolizumab for relapsed/refractory PD-L1 positive …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies [Phase 1, Phase 2]
AZD8205 is being studied in a Phase I/IIa trial as a single agent or in combination for advanced/metastatic solid tumors. Recruitment is ong…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV [Phase 1]
This is a Phase 1 clinical trial evaluating the combination of cabozantinib (XL184) and nivolumab in patients with various advanced cancers …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Megestrol Acetate for First-Line Treatment of Malnourished Non-Small Cell Lung Cancer [Phase 3]
A Phase 3 clinical trial update evaluating megestrol acetate as first-line treatment for malnourished non-small cell lung cancer; the study …
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Quick Start Durvalumab Following Chemoradiation for Stage III Nonsmall Cell Lung Cancer [Phase 2]
A Phase 2 trial is evaluating starting durvalumab after chemoradiation in patients with unresectable stage III non-small cell lung cancer. T…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01) [Phase 2]
A Phase 2 clinical trial update on pembrolizumab (Keytruda) for previously treated stage IV nonsquamous non-small cell lung cancer, currentl…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: BBO-11818 in Adult Subjects With KRAS Mutant Cancer [Phase 1]
Phase 1 trial update for BBO-11818 in adults with KRAS-mutant cancers, currently recruiting across several KRAS-driven solid tumors includin…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Targeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial) [Phase 2]
This Clinical Trials update describes the Phase 2 A LUNG-MAP trial evaluating targeted therapy for RET fusion-positive advanced non-small ce…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: A Study to Learn About PF-07921585 Alone or With Other Anti-cancer Medicines in People With Cancer [Phase 1]
A Phase 1 study of PF-07921585 alone or with other anti-cancer medicines in multiple cancers has been terminated.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Symbiotic-Lung-10: A Study to Learn About PF-08634404 Alone or in Combination in Early-stage or Locally Advanced NSCLC [Phase 2]
A Phase 2 study called Symbiotic-Lung-10 evaluating PF-08634404 alone or with a partner in early-stage or locally advanced non-small cell lu…