Non-small Cell Lung Cancer
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Multiparametric PET-MRI Integration for a New Approach to Tumor Heterogeneity in Non-Small Cell Lung Cancer (NSCLC): Pilot Study [NA]
This clinical trial evaluated multiparametric PET-MRI to study tumor heterogeneity in non-small cell lung cancer, but the pilot study has be…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial using electronic nose (E-Nose) technology to monitor treatment response in patients with non-small cell lung cancer…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Beamion 44: A Study to Test How Well Zongertinib is Tolerated by People With Advanced Non-small Cell Lung Cancer With HER2 Mutations When Given in Combination With Chemotherapy With or Without Pembrolizumab [Phase 2]
A Phase 2 trial update evaluating how well Zongertinib is tolerated when given in combination with chemotherapy with or without pembrolizuma…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: PET-CT Predicting Lymph Nodes Metastasis
Clinical trial update from Fudan University describes PET-CT as a potential predictor of lymph node metastasis in non-small cell lung cancer…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors [Phase 1]
Phase 1 clinical trial update evaluating the safety and tolerability of the radiopharmaceutical 212Pb-DOTAM-GRPR1 in adults with recurrent o…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations [Phase 3]
Phase 3 study comparing Datopotamab Deruxtecan to Docetaxel in previously treated, TROP2-positive advanced or metastatic non-squamous non-sm…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Emulation of the CheckMate 017/057 (NCT01642004 and NCT01673867) Trials Using Specialty Oncology Electronic Health Records Databases
An observational study to emulate the CheckMate 017/057 trials in advanced non-small cell lung cancer using specialty oncology electronic he…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Magnetic Resonance Imaging of the Lung: Oncological Applications
A clinical trial investigating magnetic resonance imaging (MRI) applications for lung cancer imaging is currently recruiting, focusing on no…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: The Efficacy and Safety of Narlumosbart in Combination With Stereotactic Body Radiation Therapy to Improve the Efficacy of First-line Chemotherapy Combined With Immunotherapy in Patients With Bone Metastases From Advanced Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial sponsored by Fudan University is evaluating Narlumosbart in combination with SBRT as part of first-line chemotherap…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Microbiota and the Lung Cancer [NA]
This clinical trial explores the relationship between the microbiota and non-small cell lung cancer, with the study currently active but not…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Andamertinib With or Without Platinum-doublet Chemotherapy Versus Platinum-doublet Chemotherapy in Patients With NSCLC Harboring Atypical EGFR Mutations [Phase 2]
Phase 2 trial evaluating Andamertinib with or without platinum-doublet chemotherapy versus platinum-doublet chemotherapy in patients with No…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations [Phase 2]
Phase 2 trial investigating the safety and efficacy of osimertinib in combination with amivantamab for non-small cell lung cancer with commo…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Furmonertinib Plus Radiotherapy for EGFR+ NSCLC With Pleural Effusion [Phase 2]
Phase 2 clinical trial evaluating furmonertinib plus radiotherapy for EGFR-positive non-small cell lung cancer with malignant pleural effusi…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Emulation of the KEYNOTE-042 (NCT02220894) Trial Using Specialty Oncology Electronic Health Records Databases
An update on a study that uses specialty oncology electronic health records to emulate the KEYNOTE-042 trial in advanced or metastatic non-s…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Safety and Efficacy of NK510 to Treat NSCLC [EARLY_Phase 1]
This clinical trial update indicates NK510 is being investigated for non-small cell lung cancer in an early-phase study and the trial is cur…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance [Phase 2]
Phase 2 trial evaluating MRI surveillance to reduce symptomatic brain metastases in patients with stage III non-small cell lung cancer.
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Association Between Galectin-3 Levels and Outcomes in Patients With Renal Cell Carcinoma, Transitional Cell Carcinoma , Non Small Cell Lung Cancer, and Hepatocellular Carcinoma, Treated With PD-1/PDL-1 Inhibitors
A clinical trial is investigating whether Galectin-3 levels predict outcomes in patients with renal cell carcinoma, urothelial carcinoma, no…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: UmbREALung - A Retrospective and Prospective, Observational, Real World Multi-cohort Study of Patients With Non-small Cell Lung Cancer (NSCLC) Initiating Approved Drugs Developed by AZ or as Part of an AZ Alliance
UmbREALung is a real-world, observational study in non-small cell lung cancer patients initiating approved AstraZeneca drugs or AZ Alliance …
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Boosting Osimertinib Blood Brain Barrier Penetration [Phase 2]
A Phase 2 clinical trial update from Maastricht University Medical Center describes efforts to boost brain penetration of osimertinib in non…
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EMA approval · 2026-03-19EMA Authorised: Vargatef (nintedanib) — Boehringer Ingelheim International GmbH
EMA authorised Vargatef (nintedanib) by Boehringer Ingelheim International GmbH for the treatment of non-small cell lung cancer in the Europ…
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EMA approval · 2026-03-19EMA Authorised: Imfinzi (durvalumab) — AstraZeneca AB
The European Medicines Agency has authorised Imfinzi (durvalumab) for non-small cell lung cancer. AstraZeneca AB is the marketing authorizat…
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: NOTION: iN-home Sampling Of cyTokines in ImmunOtherapy patieNts
The NOTION study investigates in-home sampling of cytokines in cancer patients receiving immunotherapy, and the trial has completed. The con…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy [Phase 2]
Phase 2 pilot study comparing outcomes of performance status 2 vs 0-1 in non-small cell lung cancer patients treated with chemotherapy and i…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Osimertinib Combined With Chemotherapy in Patients Who Had Distant Recurrence After Adjuvant Osimertinib for EGFRm Resectable SIB-IIIA NSCLC. [Phase 4]
A ClinicalTrials.gov update describes a Phase 4 trial of combining osimertinib with chemotherapy for distant recurrence after adjuvant osime…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Prediction of Outcome to Neoadjuvant Therapy in Non-small Cell Lung Cancer（NSCLC）
This clinical trial investigates predicting outcomes of neoadjuvant therapy in non-small cell lung cancer and is currently recruiting.