Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 trial evaluating HWK-007, a PTK7-directed antibody-drug conjugate, for advanced solid tumors; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients
Prospective non-interventional trial evaluating outcomes for EGFR-mutated non-small cell lung cancer patients treated with osimertinib with …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Thoracic Radiotherapy Plus Durvalumab in Elderly and/or Frail NSCLC Stage III Patients Unfit for Chemotherapy [Phase 2]
A Phase 2 study evaluated thoracic radiotherapy plus durvalumab in elderly and/or frail patients with non-small cell lung cancer stage III w…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Sacituzumab Tirumotecan Combined With Toripalimab for Resectable Stage II-IIIB NSCLC [Phase 2]
A Phase 2 clinical trial is evaluating sacituzumab govitecan in combination with toripalimab for resectable stage II-IIIB non-small cell lun…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study on the Efficacy and Safety of JSKN016 as Neoadjuvant Therapy in Resectable Stage II-III Non-small Cell Lung Cancer Patients [Phase 2]
Phase 2 trial entry for JSKN016 as neoadjuvant therapy in resectable stage II-III non-small cell lung cancer; currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC [Phase 3]
A global Phase III trial is evaluating Rilvegostomig or Pembrolizumab plus chemotherapy as first-line treatment for metastatic non-squamous …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study to Investigate Ubamatamab With and Without REGN7075 in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating Ubamatamab with and without REGN7075 in adults with advanced or metastatic non-small cell lung cancer; currently re…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Retrospective Real-World Study Based on RATIONALE-307
A clinical-trial update announcing a retrospective real-world study based on RATIONALE-307 for advanced non-small cell lung cancer. The stud…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/Resistance [Phase 2]
A Phase 2 clinical trial evaluating ASP3082 in patients with metastatic or locally advanced non-small cell lung cancer and pancreatic ductal…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: TILs Therapy for Multiple Primary Early-Stage NSCLC [EARLY_Phase 1]
Trial update for TILs therapy targeting multiple primary early-stage non-small cell lung cancer, currently in early phase 1 and not yet recr…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: TILs Plus Third-Generation EGFR-TKI Therapy for TKI-Resistant NSCLC [EARLY_Phase 1]
An early-phase (Phase 1) trial is evaluating the combination of tumor-infiltrating lymphocytes (TILs) with a third-generation EGFR-TKI for p…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 2, Phase 3]
Clinical trial update on magnesium supplementation for patients with advanced non-small cell lung cancer, a Phase 2/Phase 3 study that is no…
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EMA approval · 2026-03-26EMA Authorised: Lazcluze (lazertinib mesilate monohydrate) — Janssen Cilag International NV
The European Medicines Agency authorised Lazcluze (lazertinib mesilate monohydrate) for non-small cell lung cancer, with Janssen Cilag Inter…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07) [Phase 3]
Phase 3 clinical trial update for first-line metastatic non-small cell lung cancer evaluating datopotamab deruxtecan with pembrolizumab, wit…
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EMA approval · 2026-03-25EMA Authorised: Zirabev (bevacizumab) — Pfizer Europe MA EEIG
Zirabev (bevacizumab) has been authorised by EMA for multiple cancer indications, including colorectal, breast, non-small cell lung, renal c…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: The Efficacy and Safety of the Combination of PD-1 With Chemotherapy and Adaptive Radiotherapy Strategy in the Treatment of Stage III Non-small Cell Lung Cancer Patients [Phase 2]
A Phase 2 study is evaluating the combination of a PD-1 inhibitor (Sintilimab) with chemotherapy and adaptive radiotherapy for stage III non…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: KRAS-Specific Autologous TCR-T Cell Therapy for KRAS Mutation in Advanced Solid Tumors [Phase 1]
A Phase 1 clinical trial is evaluating a KRAS-specific autologous TCR-T cell therapy for KRAS-mutant advanced solid tumors, including colore…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Phase III Study of Envafolimab Versus Placebo Plus Chemotherapy in Resectable Stage III NSCLC [Phase 3]
A Phase III trial evaluating Envafolimab plus chemotherapy versus placebo plus chemotherapy in resectable stage III non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: A Study of IMU-201 (PD1-Vaxx), a B-Cell Immunotherapy, in Adults With Non-Small Cell Lung Cancer [Phase 1]
A Phase 1 trial of IMU-201 (PD1-Vaxx) in adults with non-small cell lung cancer has been terminated.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Fulzerasib Sequential Sintilimab Plus Platinum-Doublet Neoadjuvant Therapy for Resectable KRAS G12C-Mutant NSCLC [Phase 2]
Reports a Phase 2 clinical trial evaluating Fulzerasib sequential with Sintilimab and platinum-doublet chemotherapy as neoadjuvant therapy f…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC [Phase 2]
A Phase 2 clinical trial is evaluating high-dose intravenous ascorbate added to chemotherapy and radiation therapy for non-small cell lung c…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Study of Sotorasib in People With Non-Small Cell Lung Cancer [Phase 2]
This clinical trial update reports that a Phase 2 study of sotorasib for non-small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC [Phase 1]
A Phase 1 clinical trial update for EPI-326 in EGFR-mutant non-small cell lung cancer and head and neck squamous cell carcinoma; the study i…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Phase Ib/II Trial of Envafolimab Plus Lenvatinib for Subjects With Solid Tumors [Phase 1, Phase 2]
A Phase Ib/II trial is evaluating the combination of Envafolimab (PD-L1 inhibitor) and lenvatinib in patients with solid tumors, including n…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating adding berzosertib to standard carboplatin/gemcitabine and to pembrolizumab for patients with advan…