Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2017-06-29Clinical Trial Update: Clinical Trial of Neoadjuvant Targeted Treatment to NSCLC Patients [Phase 3]
This clinical trial update notes a Phase 3 neoadjuvant targeted therapy trial in non-small cell lung cancer with disease-free survival as th…
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CLINICAL_TRIALS research · 2017-06-27Clinical Trial Update: Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer
This clinical trials update notes a completed study collecting tissue samples from patients with non-small cell lung cancer.
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CLINICAL_TRIALS withdrawal · 2017-06-27Clinical Trial Update: Study of Immunochemotherapy +/- Hypofractionated Radiation for Complete Response in Solid Tumors [NA]
A clinical trial evaluating immunochemotherapy with optional hypofractionated radiation for complete response in solid tumors has been withd…
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Bortezomib and Pemetrexed Disodium in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial investigating bortezomib with pemetrexed disodium in advanced non-small cell lung cancer and other solid tumors; completed w…
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CLINICAL_TRIALS trial_result · 2017-06-23Clinical Trial Update: Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating whole-brain radiation therapy plus pemetrexed for brain metastases from non-small cell lung cancer; the study was t…
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FDA approval · 2017-06-22FDA Approved: MEKINIST — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for MEKINIST (trametinib) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2017-06-22Clinical Trial Update: Erlotinib Treatment Beyond Progression in EGFR Mutant NSCLC [Phase 2]
A Phase 2 clinical trial examining Erlotinib treatment beyond progression in EGFR-mutant non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2017-06-22Clinical Trial Update: To Predict Efficacy by Detecting Circulating Endothelial Cell Subsets and Blood Perfusion Parameters Changes in Vivo Tumor in Study of QL1101 and Avastin® in Patients With Non-squamous Non-small Cell Lung Cancer
A clinical trial update describing ongoing biomarker research to predict efficacy of QL1101 and bevacizumab in non-squamous non-small cell l…
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CLINICAL_TRIALS withdrawal · 2017-06-22Clinical Trial Update: Phase 2 Study of MPDL3280A Combined With CDX-1401 in NY-ESO 1 (+) IIIB, IV or Recurrent Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating MPDL3280A (atezolizumab) plus CDX-1401 in NY-ESO-1 positive non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-06-21Clinical Trial Update: A Study to Evaluate the Efficacy of Brigatinib (AP26113) in Participants With Anaplastic Lymphoma Kinase (ALK)-Positive, Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib [Phase 2]
Phase 2 trial evaluating Brigatinib in ALK-positive NSCLC patients previously treated with crizotinib has completed with results posted in 2…
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: LUX-Lung 7: A Phase IIb Trial of Afatinib(BIBW2992) Versus Gefitinib for the Treatment of 1st Line EGFR Mutation Positive Adenocarcinoma of the Lung [Phase 2]
Phase IIb trial comparing afatinib to gefitinib as first-line treatment for EGFR mutation-positive adenocarcinoma of the lung has completed …
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating a combination of chemotherapy, bevacizumab, radiation therapy, and erlotinib in patients wit…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Ruxolitinib in Combination With Pemetrexed/Cisplatin in Non Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating ruxolitinib with pemetrexed/cisplatin in non-small cell lung cancer has been terminated; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Vorinostat, Paclitaxel, and Radiation Therapy in Treating Patients Unable to Tolerate Cisplatin With Stage III Non-Small Lung Cancer That Cannot Be Removed By Surgery [Phase 1, Phase 2]
This Phase 1/2 trial evaluated a vorinostat/paclitaxel/radiation therapy regimen for patients with stage III non-small cell lung cancer who …
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Microwave Ablation in the Treatment of Stage I Non Small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial update examining microwave ablation for stage I non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: Ph II Adjuvant Carboplatin/Docetaxel in Curatively Resected Stage I-IIIA NSCLC [Phase 2]
Phase II trial evaluating adjuvant carboplatin and docetaxel in curatively resected stage I-IIIA non-small cell lung cancer. Results were po…
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CLINICAL_TRIALS trial_result · 2017-06-09Clinical Trial Update: Ph II of Vinflunine and Cetuximab in Second Line Treatment of NSCLC [Phase 2]
Phase II trial of vinflunine in combination with cetuximab for second-line non-small cell lung cancer was terminated, with results posted in…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Nintedanib in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Failed Up to Two Previous Chemotherapy Regimens [Phase 2]
Phase 2 trial evaluating nintedanib in patients with advanced non-small cell lung cancer who progressed after up to two prior chemotherapy r…
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Safety and Pharmacokinetics of Escalating Doses of DNIB0600A in Participants With Non-Small Cell Lung Cancer (NSCLC) and Platinum Resistant Ovarian Cancer [Phase 1]
Phase 1 trial update evaluating the safety and pharmacokinetics of escalating doses of DNIB0600A in participants with non-small cell lung ca…
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CLINICAL_TRIALS research · 2017-06-07Clinical Trial Update: Study on Potential Biomarkers Associated With Clinical Phenotype of EGFR-TKIs in No-small Cell Lung Cancer in China
A clinical trial update examining potential biomarkers associated with the clinical phenotype of EGFR-TKI therapy in non-small cell lung can…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Erlotinib With or Without Hydroxychloroquine in Chemo-Naive Advanced NSCLC and (EGFR) Mutations [Phase 2]
Phase 2 trial evaluating erlotinib with or without hydroxychloroquine in chemo-naive advanced non-small cell lung cancer with EGFR mutations…
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Study Evaluating the Addition of Fulvestrant to Erlotinib in Stage IIIB/IV Non-Small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating the addition of fulvestrant to erlotinib in stage IIIB/IV non-small cell lung cancer was terminated; results were p…
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CLINICAL_TRIALS withdrawal · 2017-06-05Clinical Trial Update: ENB Robotic ICG Guided Surgery: A Novel Technique for Targeting Small Lung Tumors [Phase 1]
Phase 1 clinical trial of ENB robotic ICG guided surgery for targeting small lung tumors in non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-06-02Clinical Trial Update: A Randomized Phase II Study of SUBATM-itraconazole in Patients With Untreated Squamous NSCLC. [Phase 2]
A randomized Phase II study of SUBATM-itraconazole in untreated metastatic non-small cell lung cancer was terminated; results posted in 2017…
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Observational Study to Evalute the Efficacy and Safety of Avastin (Bevacizumab) in Addition to Platinum-Based Chemotherapy for First-Line Treatment of Participants With Non-Small Cell Lung Cancer
This update reports the completion of an observational study evaluating Avastin (bevacizumab) added to platinum-based chemotherapy as first-…