Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-26Clinical Trial Update: An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026) [Phase 3]
Phase 3 trial comparing nivolumab to investigator's choice chemotherapy as first-line therapy in stage IV or recurrent PD-L1+ non-small cell…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: The Value of Surgical Mediastinal Staging in Clinical N1 Lung Cancer
This update reports on a completed clinical trial evaluating the value of surgical mediastinal staging in patients with clinical N1 non-smal…
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CLINICAL_TRIALS research · 2017-07-25Clinical Trial Update: The Utility of FDG-PET for Radiation Treatment in NSCLC
Update on a clinical trial evaluating the use of FDG-PET imaging to guide radiation treatment in non-small cell lung cancer.
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CLINICAL_TRIALS research · 2017-07-24Clinical Trial Update: The Predicted Potential of Quantitative T Cell Repertoire(TCR) in Anti-PD-L1 Treatment in NSCLC Patients
This clinical trial update discusses the potential of using quantitative T cell receptor repertoire analysis to predict response to anti-PD-…
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FDA approval · 2017-07-21FDA Approved: XALKORI — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for XALKORI (crizotinib) filed by Pfizer, authorizing a change or addition to the drug’s labeling/in…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: AZD9291 (Osimertinib) Versus Platinum-Based Doublet-Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing osimertinib (AZD9291) versus platinum-based doublet chemotherapy in locally advanced or metastatic non-small cell lu…
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CLINICAL_TRIALS withdrawal · 2017-07-21Clinical Trial Update: Crizotinib Expanded Access Protocol For ROS1 Positive NSCLC
Pfizer's expanded access protocol for crizotinib in ROS1-rearranged non-small cell lung cancer is no longer available.
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Assess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment. [Phase 2]
Phase 2 trial evaluating AZD6244 with docetaxel for second-line non-small cell lung cancer has completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-07-18Clinical Trial Update: A Study Of Dacomitinib (PF-00299804) In Patients With Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 study results for dacomitinib in advanced non-small cell lung cancer have been posted.
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: A Multicenter Randomized Phase III Study Comparing Second-line Treatment With Chemotherapy Associated or Not to Erlotinib in NSCLC Patients With Secondary Resistance to TKI-EGFR [Phase 3]
This clinical trial update reports a multicenter Phase III randomized study comparing second-line chemotherapy with or without erlotinib in …
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in NSCLC Cachexia [NA]
A pilot study evaluating the safety and tolerability of Nutrifriend Cachexia in cancer cachexia and non-small cell lung cancer has completed…
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CLINICAL_TRIALS trial_result · 2017-07-14Clinical Trial Update: Recombinant Human Endostatin Continued Pumping Into Vein Combining With CCRT in Unresectable Stage III NSCLC [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating recombinant human endostatin given by continuous infusion with concurrent chemoradiotherapy in unresecta…
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CLINICAL_TRIALS research · 2017-07-14Clinical Trial Update: LUMINIST: LUng Cancer Molecular Insights Non Interventional Study
AstraZeneca-sponsored non-interventional study in non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies [NA]
Clinical trial update on early palliative care in advanced lung and gastrointestinal malignancies; status completed with results posted in 2…
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CLINICAL_TRIALS research · 2017-07-12Clinical Trial Update: Hypofractionated Radiotherapy (Stereotactic) Versus Conventional Radiotherapy for Inoperable Early Stage I Non-small Cell Lung Cancer (NSCLC) [Phase 3]
A Phase 3 trial compares hypofractionated stereotactic radiotherapy with conventional radiotherapy for inoperable early-stage non-small cell…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1) [Phase 3]
ROMANA 1 is a Phase 3 trial evaluating the safety and efficacy of anamorelin HCl in patients with non-small cell lung cancer-associated cach…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Carboplatin, Pemetrexed Disodium, and Bevacizumab for Patients With Stage III or IV Non-Small Cell Lung Cancer Who Are Light/Never Smokers [Phase 2]
Phase 2 trial of a carboplatin/pemetrexed disodium/bevacizumab regimen in stage III or IV non-small cell lung cancer for light/never smokers…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 2) [Phase 3]
Phase 3 ROMANA 2 trial results evaluate anamorelin hydrochloride for cancer cachexia in non-small cell lung cancer; the study is completed w…
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CLINICAL_TRIALS trial_result · 2017-07-11Clinical Trial Update: Anamorelin HCl in the Treatment of Non-Small Cell Lung Cancer-Cachexia (NSCLC-C): An Extension Study (ROMANA 3) [Phase 3]
Phase 3 extension study ROMANA 3 evaluated anamorelin HCl for NSCLC-associated cachexia; results completed and posted in 2017.
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CLINICAL_TRIALS withdrawal · 2017-07-11Clinical Trial Update: A Study for Subjects Who Are Participating in an Astellas-sponsored ASP8273 Study [Phase 2]
This clinical trial update notes that the Phase 2 study of ASP8273 for subjects with non-small cell lung cancer with EGFR activating mutatio…
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CLINICAL_TRIALS trial_result · 2017-07-06Clinical Trial Update: Combination Vaccine Immunotherapy (DRibbles) for Patients With Definitively-Treated Stage III Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial of DRibbles vaccine immunotherapy for patients with definitively treated stage III non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2017-07-05Clinical Trial Update: Neo-MASCT Immunotherapy for Advanced NSCLC. [Phase 1, Phase 2]
This entry reports an update on a Neo-MASCT immunotherapy trial for advanced non-small cell lung cancer (stage IV) in Phase 1 and Phase 2. T…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: A Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing Therapy [Phase 3]
Phase 3 trial comparing atezolizumab to docetaxel in locally advanced or metastatic non-squamous non-small cell lung cancer after platinum t…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: A Phase I Trial of SS1 (dsFv) PE38 With Paclitaxel, Carboplatin, and Bevacizumab in Subjects With Unresectable Non-Small Cell Lung Adenocarcinoma [Phase 1]
This Phase I trial investigates SS1 (dsFv) PE38 combined with paclitaxel, carboplatin, and bevacizumab in patients with unresectable non-sma…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial update evaluating adjuvant therapy based on gene expression for stage IA and IB non-small cell lung cancer; study completed wi…