Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Comparison of Cost-effectiveness of Continuation Maintenance Therapy With Six Cycles of Pemetrexed Versus Pemetrexed Until Disease Progression for Metastatic Non-squamous Non-small-cell Lung Cancer
A clinical trial update evaluating the cost-effectiveness of continuation maintenance therapy with six cycles of pemetrexed versus pemetrexe…
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CLINICAL_TRIALS withdrawal · 2017-11-06Clinical Trial Update: Ph2 Nab-paclitaxel With Gemcitabine to Determine Efficacy in Advanced Non-squamous NSCLC. [Phase 2]
A Phase 2 trial evaluating nab-paclitaxel combined with gemcitabine for advanced non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: PET Response During Chemoradiation of Lung Cancer [NA]
A completed clinical trial update evaluating PET response during chemoradiation for non-small cell lung cancer.
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CLINICAL_TRIALS research · 2017-10-27Clinical Trial Update: EGFR-TKI Concurrent With/Without WBRT in Brain Metastasis From NSCLC [Phase 3]
A Phase 3 clinical trial is evaluating the use of an EGFR tyrosine kinase inhibitor with or without whole-brain radiotherapy in patients wit…
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CLINICAL_TRIALS trial_result · 2017-10-26Clinical Trial Update: Docetaxel and Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer or Other Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating docetaxel and erlotinib in advanced non-small cell lung cancer and other solid tumors has completed with…
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CLINICAL_TRIALS trial_result · 2017-10-25Clinical Trial Update: Neoadjuvant Chemo for Non-metastatic Non-small Cell Lung Cancer [Phase 2]
Phase 2 neoadjuvant chemotherapy study for non-metastatic non-small cell lung cancer was terminated; results posted in 2017.
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CLINICAL_TRIALS research · 2017-10-25Clinical Trial Update: Crizotinib in Pretreated Metastatic Non-small-cell Lung Cancer With MET Amplification or ROS1 Translocation (METROS) [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating crizotinib in pretreated metastatic non-small-cell lung cancer with …
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CLINICAL_TRIALS trial_result · 2017-10-24Clinical Trial Update: A Study Examining Long Response in Lung Cancer Patients Treated With Tarceva (Erlotinib)
A completed clinical trial update examining long-term responses in non-small cell lung cancer patients treated with Tarceva (erlotinib), wit…
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CLINICAL_TRIALS trial_result · 2017-10-19Clinical Trial Update: Efficacy and Safety Study of ABP 215 Compared With Bevacizumab in Patients With Advanced Non-Small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing ABP 215 with bevacizumab in advanced non-small cell lung cancer has completed. Results were posted in October 2017.
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Fludeoxyglucose F 18 in Detecting Lymph Node Metastasis in Patients With Stage I or Stage II Non-Small Cell Lung Cancer That Can Be Removed by Surgery [NA]
Clinical trial assessing the use of Fludeoxyglucose F-18 PET imaging to detect lymph node metastasis in patients with stage I or stage II no…
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CLINICAL_TRIALS research · 2017-10-13Clinical Trial Update: Lung Cancer Surgery: Decisions Against Life Saving Care - The Intervention [NA]
This entry notes the completion of a UNC-led clinical trial examining decisions around life-saving care in non-small cell lung cancer surger…
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FDA approval · 2017-10-02FDA Approved: ALUNBRIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
The FDA approved a supplemental application for ALUNBRIG (brigatinib) from Takeda, resulting in updates to its labeling.
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CLINICAL_TRIALS trial_result · 2017-09-26Clinical Trial Update: Early Prediction of Pathology Response of Chemoradiotherapy With FLT PET [NA]
Clinical trial update for early prediction of pathology response using FLT PET in chemoradiotherapy, terminated with posted results.
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CLINICAL_TRIALS trial_result · 2017-09-21Clinical Trial Update: LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial comparing ceritinib (LDK378) to chemotherapy in previously untreated ALK-rearranged non-small cell lung cancer; results posted…
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CLINICAL_TRIALS trial_result · 2017-09-19Clinical Trial Update: Microwave Plus Chemotherapy Versus Chemotherapy for Advanced NSCLC [Phase 3]
Phase 3 trial comparing microwave therapy plus chemotherapy versus chemotherapy alone for advanced non-small cell lung cancer; status not di…
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: A Study of Bevacizumab in Combination With Standard of Care Treatment in Participants With Advanced Non-squamous Non-small Cell Lung Cancer (NSCLC) [Phase 3]
Phase 3 study evaluating bevacizumab in combination with standard of care in advanced non-squamous non-small cell lung cancer has completed …
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CLINICAL_TRIALS trial_result · 2017-09-18Clinical Trial Update: Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer（ALTER0303） [Phase 2, Phase 3]
Clinical trial update for Anlotinib in advanced non-small cell lung cancer (ALTER0303) reporting completed Phase 2 and Phase 3 studies.
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FDA approval · 2017-09-14FDA Approved: MVASI — Original Application (Amgen, Inc)
The FDA approved MVASI (bevacizumab-awwb) from Amgen as a biosimilar to Avastin, marking the original application granting U.S. approval for…
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CLINICAL_TRIALS trial_result · 2017-09-14Clinical Trial Update: Postoperative NSCLC Treated With Integrated Medicine Base on Circulating Tumor Cell Detection [Phase 3]
A Phase 3 clinical trial update investigates postoperative non-small cell lung cancer treated with an integrated medicine approach guided by…
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CLINICAL_TRIALS trial_result · 2017-09-12Clinical Trial Update: Erlotinib as Neoadjuvant Treatment in Patients With Stage ⅢA N2 NSCLC With Activating EGFR Mutation. [Phase 2]
Phase 2 trial evaluating erlotinib as neoadjuvant treatment in stage IIIA N2 non-small cell lung cancer with activating EGFR mutation has co…
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CLINICAL_TRIALS trial_result · 2017-09-11Clinical Trial Update: Neratinib With and Without Temsirolimus for Patients With HER2 Activating Mutations in Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 trial evaluated neratinib with and without temsirolimus in patients with HER2-activating mutations in non-small cell lung cancer; …
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CLINICAL_TRIALS research · 2017-08-30Clinical Trial Update: Study to Evaluate Resistance Mechanisms and Real-world Pharmacoeconomics of Crizotinib in NSCLC Patients
Clinical trial update examining resistance mechanisms to crizotinib and real-world pharmacoeconomics in patients with metastatic non-small c…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC [Phase 3]
Phase 3 trial evaluating selumetinib plus docetaxel for second-line KRAS-positive non-small cell lung cancer; results were posted in 2017 an…
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CLINICAL_TRIALS trial_result · 2017-08-29Clinical Trial Update: the Clinical Trial of Gefitinib(Non - Small Cell Lung Cancer) [Phase 4]
A Phase 4 trial of gefitinib for non-small cell lung cancer is updated. The current trial status is listed as UNKNOWN.
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CLINICAL_TRIALS trial_result · 2017-08-28Clinical Trial Update: Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating denosumab in combination with chemotherapy as first-line treatment for metastatic non-small cell lung ca…