Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-12-04Clinical Trial Update: A Study in Ovarian, Non-Small Cell Lung, Prostate, Colorectal, Gastroesophageal Cancers, and Squamous Cell Carcinoma of the Head and Neck [Phase 2]
Phase 2 clinical trial update across multiple cancer types including ovarian, non-small cell lung, prostate, colorectal, gastric/esophageal,…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: A Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy or Immunotherapy in Participants With Non-small Cell Lung Cancer (MK-3475-021/KEYNOTE-021) [Phase 1, Phase 2]
Clinical trial update for pembrolizumab combined with chemotherapy or immunotherapy in non-small cell lung cancer (KEYNOTE-021) from phase 1…
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CLINICAL_TRIALS withdrawal · 2017-11-30Clinical Trial Update: Combination of Platinum Doublets and Hypofractionated Radiotherapy in NSCLC [Phase 2]
A phase 2 trial evaluating platinum doublets with hypofractionated radiotherapy for non-small cell lung cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Bronchial Artery Infusion of Gemcitabine in Treating Patients With Recurrent or Progressive Non-Small Cell Lung Cancer [Phase 1]
The document reports a Phase 1 trial evaluating bronchial artery infusion of gemcitabine for recurrent or progressive non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Oxaliplatin, Docetaxel, and Radiation Therapy in Treating Patients With Unresectable Stage II/III or Recurrent NSCLC [Phase 1]
Phase 1 trial evaluating oxaliplatin and docetaxel with radiation therapy in unresectable stage II/III or recurrent non-small cell lung canc…
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Genotype-Driven Treatment of Advanced Non-small Cell Lung Cancer Based on mRNA Expression of ERCC1 & RRM1 as First-line Chemotherapy [Phase 2]
This Phase 2 trial in advanced non-small cell lung cancer investigates genotype-guided first-line chemotherapy based on ERCC1 and RRM1 mRNA …
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: A Dose-escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of GDC-0032 in Combination With Docetaxel or With Paclitaxel in Patients With HER2-negative Locally Recurrent or Metastatic Breast Cancer or Non-small Cell Lung Cancer [Phase 1]
Phase 1 dose-escalation study evaluating safety, tolerability, and pharmacokinetics of GDC-0032 (taselisib) in combination with docetaxel or…
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Intercalating and Maintenance Gefitinib in Combination With Chemotherapy for Advanced EGFR-mutant NSCLC [Phase 4]
Phase 4 trial evaluating intercalating and maintenance gefitinib with chemotherapy for advanced EGFR-mutant non-small cell lung cancer has b…
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CLINICAL_TRIALS trial_result · 2017-11-22Clinical Trial Update: A Study of Trastuzumab Emtansine in Participants With Human Epidermal Growth Factor Receptor (HER)2 Immunohistochemistry (IHC)-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial evaluating trastuzumab emtansine in HER2 IHC-positive locally advanced or metastatic non-small cell lung cancer has completed …
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CLINICAL_TRIALS trial_result · 2017-11-22Clinical Trial Update: NPI-0052 and Vorinostat in Patients With Non-small Cell Lung Cancer, Pancreatic Cancer, Melanoma or Lymphoma [Phase 1]
Phase 1 trial update of NPI-0052 (marizomib) and vorinostat in patients with non-small cell lung cancer, pancreatic cancer, melanoma, lympho…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Study of Linifanib (ABT-869) in Combination With Carboplatin/Paclitaxel in Japanese Subjects With Non-Small Cell Lung Cancer (NSCLC) [Phase 1]
Phase 1 study evaluating linifanib (ABT-869) in combination with carboplatin and paclitaxel in Japanese patients with non-small cell lung ca…
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CLINICAL_TRIALS trial_result · 2017-11-21Clinical Trial Update: A Phase 1b Study With Volociximab in Combination With Carboplatin and Paclitaxel in First-line, Advanced Non-Small Cell Lung Cancer (NSCLC) [Phase 1]
This clinical trial update reports completion of a Phase 1b study of volociximab in combination with carboplatin and paclitaxel as first-lin…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Efficiency of Icotinib in Plasma ctDNA EGFR Mutation-positive Patients Diagnosed With Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating icotinib in plasma ctDNA EGFR mutation-positive non-small cell lung cancer patients.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Phase I Study Of Pazopanib With Either Erlotinib Or Pemetrexed In Patients With Advanced Solid Tumors [Phase 1]
A Phase I study evaluating pazopanib in combination with either erlotinib or pemetrexed in patients with advanced solid tumors, including no…
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CLINICAL_TRIALS research · 2017-11-17Clinical Trial Update: Apatinib Combine With Platinum-Based Doublet Chemotherapy for First-line Treatment of Advanced NSCLC [Phase 1, Phase 2]
A phase 1/2 trial is evaluating apatinib in combination with platinum-based doublet chemotherapy as first-line treatment for advanced non-sm…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: IR-guided Ablation (IRGA) Combined With Stereotactic Ablative Radiation (SABR) for Large Lung Tumors [Phase 1]
Phase 1 trial of IR-guided ablation combined with stereotactic ablative radiation for large recurrent non-small cell lung cancer has been te…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Phase II Trial of Lapatinib (TYKERB) + Pemetrexed (ALIMTA) in Advanced Non Small Cell Lung Cancer With an Initial Dose Finding Phase [Phase 1]
Phase II trial of lapatinib (TYKERB) plus pemetrexed (ALIMTA) in advanced non-small cell lung cancer has completed. The study included an in…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: A Phase I, Open-label, Study of Pazopanib in Combination With Gemcitabine and Gemcitabine Plus Cisplatin for Advanced Solid Tumors [Phase 1]
A Phase I, open-label study evaluating pazopanib in combination with gemcitabine, with or without cisplatin, in patients with advanced solid…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: EGFR Mutation Positive NSCLC Patients With Gefitinib and Thalidomide [Phase 2]
Phase 2 trial evaluating gefitinib plus thalidomide in EGFR-mutant non-small cell lung cancer. The current status of the trial is unknown.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Study of Pazopanib and Paclitaxel in Advanced Non-small Cell Lung Cancer [Phase 1]
A Phase 1 study evaluating the combination of pazopanib with paclitaxel in advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: Nab-Paclitaxel Versus Paclitaxel Plus Carboplatin in Advanced Squamous Cell Non Small Cell Lung Cancer [Phase 3]
A Phase 3 trial comparing nab-paclitaxel to paclitaxel plus carboplatin in advanced squamous cell non-small cell lung cancer; the study stat…
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CLINICAL_TRIALS research · 2017-11-09Clinical Trial Update: Explore Intra-tumor Heterogeneity and Prognostic Value of Postoperative Blood ctDNA of ⅡA - ⅢA Stage Non-squamous NSCLC Based on the Capture-based Sequencing and UMI Technology of Burning Rock
A clinical trial update investigating intra-tumor heterogeneity and the prognostic value of postoperative ctDNA in stage IIA to IIIA non-squ…
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FDA approval · 2017-11-06FDA Approved: GILOTRIF — Supplemental Application (Boehringer Ingelheim Pharmaceuticals, Inc.)
The FDA approved a supplemental application for GilotrIF (afatinib) filed by Boehringer Ingelheim Pharmaceuticals, Inc. The action appears t…
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FDA approval · 2017-11-06FDA Approved: ALECENSA — Supplemental Application (Genentech, Inc.)
FDA has approved a supplemental application for Alecensa (alectinib hydrochloride) from Genentech, expanding its labeling.
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CLINICAL_TRIALS research · 2017-11-06Clinical Trial Update: Hypofractionated vs. Conventionally Fractionated Concurrent CRT for Unresectable Stage III NSCLC [Phase 3]
An update on a Phase 3 clinical trial comparing hypofractionated versus conventionally fractionated concurrent chemoradiation therapy for un…