Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Mechanism of Response to IMFINZI Neoadjuvant Therapy in Non-small Cell Lung Cancer Patients Based on Multiple-omics Models [Phase 1, Phase 2]
A clinical trial update investigating mechanisms of response to IMFINZI neoadjuvant therapy in non-small cell lung cancer using multiple-omi…
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CLINICAL_TRIALS trial_result · 2023-03-28Clinical Trial Update: AZD9291, an Irreversible EGFR-TKI, in Relapsed EGFR-mutated Non-small Cell Lung Cancer Patients Previously Treated With an EGFR-TKI, Coupled to Extensive Translational Studies [Phase 2]
Phase 2 clinical trial update of AZD9291 (osimertinib) in relapsed EGFR-mutated non-small cell lung cancer after prior EGFR-TKI treatment, w…
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CLINICAL_TRIALS trial_result · 2023-03-27Clinical Trial Update: Efficacy Study of Osimertinib in Treatment-naïve Patients With EGFR Mutant NSCLC According to TP53 Mutational Status. [Phase 4]
A Phase 4 clinical trial assessing the efficacy of osimertinib in treatment-naïve EGFR-mutant non-small cell lung cancer, stratified by TP53…
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FDA approval · 2023-03-24FDA Approved: TABRECTA — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for Tabrecta (capmatinib) by Novartis Pharmaceuticals Corporation, expanding the label for MET e…
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: Study Comparing Bevacizumab + Erlotinib vs Erlotinib Alone as First Line Treatment of Patients With EGFR Mutated Advanced Non Squamous Non Small Cell Lung Cancer [Phase 3]
A phase 3 clinical trial comparing bevacizumab plus erlotinib versus erlotinib alone as first-line treatment for EGFR-mutated advanced non-s…
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: MILES-3: Cisplatin in Combination With Gemcitabine for Elderly Patients With Lung Cancer [Phase 3]
Phase 3 trial evaluating cisplatin in combination with gemcitabine for elderly patients with non-small cell lung cancer (metastatic or stage…
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: MILES-4: Study Comparing Gemcitabine and Pemetrexed, With or Without Cisplatin, in Patients With Nonsquamous Lung Cancer [Phase 3]
Phase 3 trial comparing gemcitabine and pemetrexed with or without cisplatin in nonsquamous non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: Chemo-immunotherapy Induction Followed by Hypo-radiotherapy in LA-NSCLC(CHIC) [Phase 2]
Phase 2 clinical trial update investigating chemo-immunotherapy induction followed by hypo-radiotherapy in locally advanced non-small cell l…
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FDA approval · 2023-03-23FDA Approved: TEPMETKO — Supplemental Application (EMD Serono, Inc.)
The FDA approved a supplemental application for Tepmetko (tepotinib hydrochloride) submitted by EMD Serono, Inc., to update/expand the drug'…
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CLINICAL_TRIALS trial_result · 2023-03-23Clinical Trial Update: Pembrolizumab Plus Pemetrexed for Elderly Patients With Non-Sq NSCLC With PD-L1 < 50%: CJLSG1901 [Phase 2]
Phase 2 trial evaluating pembrolizumab plus pemetrexed in elderly patients with non-squamous non-small cell lung cancer and PD-L1 < 50%.
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CLINICAL_TRIALS trial_result · 2023-03-23Clinical Trial Update: Study of Rofecoxib and Prolonged Constant Infusion of Gemcitabine in the Polychemotherapy Treatment of Advanced NSCLC [Phase 2, Phase 3]
Phase 2/3 trial investigating rofecoxib with prolonged gemcitabine infusion in advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-03-23Clinical Trial Update: Study of Polymeric Micellar Paclitaxel, Platinum Combined With Sindilizumab Injection for Advanced Non-squamous NSCLC [Phase 2]
Phase 2 trial update for a combination of polymeric micellar paclitaxel, platinum, and sindilizumab in advanced non-squamous non-small cell …
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CLINICAL_TRIALS trial_result · 2023-03-22Clinical Trial Update: PD-L1 Expression in Lung Cancer [Phase 2]
Phase 2 trial update examining PD-L1 expression in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-03-20Clinical Trial Update: Efficacy of SRT as Salvage Therapy in Patients With Brain Oligo-progression of EGFR-mutant Non-small Cell Lung Cancer After Failure of the Third-generation EGFR-TKIs [Phase 2]
A Phase 2 trial evaluating SRT as salvage therapy for brain oligoprogression in EGFR-mutant non-small cell lung cancer after failure of thir…
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FDA label_change · 2023-03-17FDA Approved: LUMAKRAS — Supplemental Application (Amgen Inc)
FDA approved a supplemental application for LUMAKRAS (sotorasib) from Amgen, resulting in a labeling update related to the drug.
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CLINICAL_TRIALS trial_result · 2023-03-17Clinical Trial Update: Study CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC) [Phase 1, Phase 2]
Clinical trial update for CB-839 in combination with nivolumab in melanoma, clear cell renal cell carcinoma, and non-small cell lung cancer …
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CLINICAL_TRIALS trial_result · 2023-03-17Clinical Trial Update: Assessing an Oral EGFR Inhibitor,YK-209A in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR [Phase 1, Phase 2]
Clinical trial update for an oral EGFR inhibitor YK-209A in advanced non-small cell lung cancer (Phase 1/Phase 2) with unknown status.
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Paclitaxel-bevacizumab in Advanced Lung Cancer [Phase 3]
Phase 3 clinical trial update for paclitaxel-bevacizumab in non-squamous non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Early or Delayed Intervention of Brain Radiotherapy Combined With Almonertinib in EGFR Mutated NSCLC With Brain Metastases [Phase 3]
Phase 3 trial investigating early or delayed brain radiotherapy combined with almonertinib in EGFR-mutated non-small cell lung cancer with b…
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Maintenance After Induction Chemotherapy in Elderly Patients With Advanced Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating maintenance therapy after induction chemotherapy in elderly patients with advanced non-small cell lung cancer has c…
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Chemotherapy for Lung Cancer in HIV-positive Patients [Phase 2]
A Phase 2 clinical trial assessing chemotherapy for non-small cell lung cancer in HIV-positive patients has completed.
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CLINICAL_TRIALS trial_result · 2023-03-13Clinical Trial Update: A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating NKTR-214 in combination with nivolumab and other anti-cancer therapies in select advanced solid tumors completed …
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CLINICAL_TRIALS trial_result · 2023-03-13Clinical Trial Update: Re-introduction of Pemetrexed and Cisplatin With Prolonged Angiogenic Blocking by Bevacizumab in Advanced Lung Cancer. [Phase 2]
Phase 2 trial updating re-introduction of pemetrexed and cisplatin with prolonged anti-angiogenic therapy using bevacizumab in metastatic no…
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
Clinical trial update for bempegaldesleukin and pembrolizumab, with or without chemotherapy, in locally advanced or metastatic solid tumors;…
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CLINICAL_TRIALS trial_result · 2023-03-08Clinical Trial Update: Immunological Variables Associated to ICI Toxicity in Cancer Patients [Phase 2]
A Phase 2 clinical trial investigating immunological variables associated with immune checkpoint inhibitor toxicity in cancer patients.