Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Radiation and Immune Checkpoints Blockade in Metastatic NSCLC (BMS # CA209-632) [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating radiation combined with immune checkpoint blockade in metastatic non-small cell lung cancer was termin…
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FDA approval · 2023-04-21FDA Approved: PEMETREXED — Supplemental Application (Sandoz Inc.)
The FDA approved a supplemental application for pemetrexed disodium, enabling the generic pemetrexed product from Sandoz Inc. to be marketed…
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Aumolertinib Adjuvant Therapy of Resectable Stage I EGFRm+ NSCLC With High-grade Patterns [Phase 2]
A phase 2 clinical trial exploring adjuvant aumolertinib after resection for resectable stage I EGFRm+ non-small cell lung cancer with high-…
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Non Small Cell Lung Cancer Trial of Durvalumab and Tremelimumab in Advanced Epidermal Growth Factor Receptor (EGFR) Mutant Disease. [Phase 2]
Phase 2 trial evaluating durvalumab and tremelimumab in adults with EGFR-mutant advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Evolution of the Heart Function When Monitoring Immunotherapies Anti-cancerous Inhibiting PD-1 [Phase 4]
Phase 4 clinical trial update evaluating heart function during PD-1–inhibiting immunotherapy in melanoma and non-small cell cancer patients.
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CLINICAL_TRIALS trial_result · 2023-04-14Clinical Trial Update: Furmonertinib in Patients With Leptomeningeal Metastases Associated With EGFR Mutated NSCLC [Phase 2]
Phase 2 clinical trial update for furmonertinib in patients with leptomeningeal metastases associated with EGFR-mutated non-small cell lung …
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: A Study of Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer [Phase 2]
A Phase 2 study evaluating the combination of atezolizumab and bevacizumab in EGFR mutation-positive stage IIIB-IV non-squamous non-small ce…
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: Aumolertinib Combined Intrathecal Chemotherapy for Leptomeningeal Metastasis From EGFR-Mutated NSCLC and Prognostic Value of Dynamic Changes in cfDNA Profiles [Phase 2]
A Phase 2 clinical trial evaluates aumolertinib combined with intrathecal chemotherapy for leptomeningeal metastasis in EGFR-mutated non-sma…
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: Phase I/II Study of SY-5007, a RET Inhibitor, in Patients With RET-altered Advanced Solid Tumor [Phase 1, Phase 2]
Phase I/II clinical trial update for SY-5007, a RET inhibitor, in RET-altered advanced solid tumors including non-small cell lung cancer and…
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CLINICAL_TRIALS trial_result · 2023-04-11Clinical Trial Update: Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies [Phase 2]
A Phase 2 trial evaluating molecular profiling-guided targeted therapy across advanced non-small cell lung cancer, small cell lung cancer, a…
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of HLX208+HLX10 in NSCLC With BRAF V600E Mutation [Phase 1, Phase 2]
A Phase Ib/II trial evaluating the safety and efficacy of HLX208 plus HLX10 in non-small cell lung cancer with BRAF V600E mutation, currentl…
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CLINICAL_TRIALS trial_result · 2023-04-07Clinical Trial Update: Maintenance Chemotherapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Chemotherapy for Stage IV Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II Trial [Phase 2]
A randomized Phase II trial comparing maintenance chemotherapy alone versus maintenance chemotherapy plus consolidative SBRT for stage IV no…
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CLINICAL_TRIALS trial_result · 2023-04-06Clinical Trial Update: Study to Investigate the Efficacy and Safety of WX-0593 in ALK Positive Non-Small Cell Lung Cancer (NSCLC) Patients [Phase 2]
Phase 2 clinical trial investigating WX-0593 in ALK-positive non-small cell lung cancer (NSCLC) patients.
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations [Phase 3]
A Phase 3 trial comparing YK-029A to platinum-based chemotherapy as first-line treatment for advanced/metastatic NSCLC with EGFR exon 20 ins…
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: Armatinib Alone or in Combination With SRT for Brain Metastases EGFR-mutated Non-small Cell Lung Cancer [Phase 3]
Phase 3 trial exploring armatinib alone or with SRT for brain metastases in EGFR-mutated non-small cell lung cancer; currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: Efficacy and Safety of PVT-1 Treatment in Patients With Advanced Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial update evaluating efficacy and safety of PVT-1 treatment in advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-04-05Clinical Trial Update: A Phase Ⅱ Trial of Neoadjuvant Toripalimab Plus Platinum-doublet Chemotherapy in Locally Advanced NSCLC. [Phase 2]
Phase II neoadjuvant trial evaluating toripalimab plus platinum-doublet chemotherapy in locally advanced non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: Re-Induction After Initial Response With Immune Therapy With Radiotherapy in Lung Cancer [Phase 2]
Phase 2 trial evaluating re-induction with immune therapy plus radiotherapy in stage IV non-small cell lung cancer after initial response.
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC [Phase 3]
A Phase 3 clinical trial update investigating atezolizumab with carboplatin, paclitaxel, and bevacizumab in NSCLC patients with EGFR mutatio…
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CLINICAL_TRIALS trial_result · 2023-04-03Clinical Trial Update: Trial Involving Subjects Over 70 Years of Age With Non Small-cell Lung Cancer of Stage IV and Comparing a "Classical" Strategy of Treatment Allocation, With an"Optimized" Strategy Allocating the Same Treatments [Phase 3]
Phase 3 trial comparing a 'classical' treatment allocation strategy versus an 'optimized' strategy for subjects with advanced non-small cell…
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CLINICAL_TRIALS trial_result · 2023-03-31Clinical Trial Update: Foundation and Clinical About the Expression of PD-1 in Peripheral Blood T Lymphocytes [Phase 2]
Phase 2 clinical trial update examining PD-1 expression in peripheral blood T cells for non-small cell lung cancer has been completed.
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Osimertinib Combined With Bevacizumab in Patients With Brain Metastasis Epidermal Growth Factor Receptor (EGFR) Mutation Positive Metastatic Non-Small Cell Lung Cancer [Phase 3]
Phase 3 clinical trial evaluating osimertinib in combination with bevacizumab for patients with brain metastases from EGFR-mutant metastatic…
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Osimertinib Combined With Bevacizumab in the Treatment Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions Metastatic Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating osimertinib in combination with bevacizumab for EGFR exon 20 insertion metastatic non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Chemotherapy Combines With Bevacizumab and PD-1 Inhibitor in Non-squamous NSCLC [Phase 2]
Phase 2 trial evaluating chemotherapy with bevacizumab and a PD-1 inhibitor in non-squamous non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Phase II Study of Afatinib Plus Bevacizumab in the Treatment Epidermal Growth Factor Receptor (EGFR) Exon G719X, S768I, and L861Q Mutation Metastatic Non-Small Cell Lung Cancer [Phase 2]
Phase II study investigating afatinib plus bevacizumab for metastatic non-small cell lung cancer with EGFR G719X, S768I, and L861Q mutations…