Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: Synergistic Effect of Elemene Plus TKIs Compared With TKIs in EGFR-mutated Advanced NSCLC：Prospective Study [Phase 4]
A Phase 4 clinical trial assessing the synergistic effect of elemene plus TKIs versus TKIs alone in EGFR-mutated advanced non-small cell lun…
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: Adebrelimab Combined With Bevacizumab and Docetaxel for Advanced Non-Squamous Non-small Cell Lung Cancer After Progression on First-line Immunotherapy [Phase 2]
Phase 2 trial evaluating adequatrelimab with bevacizumab and docetaxel in advanced non-squamous non-small cell lung cancer after progression…
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: Erlotinib Combined With Chemotherapy in TKI Resistant Non-Small Cell Lung Cancers [Phase 2]
Phase 2 trial evaluating erlotinib plus chemotherapy in TKI-resistant non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: Study of Anlotinib Combined With Docetaxel in Non-Driver Mutation Non-squamous NSCLC: the Save Study [Phase 2]
Phase 2 trial investigating anlotinib combined with docetaxel in non-driver mutation non-squamous non-small cell lung cancer (NSCLC).
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL) [Phase 3]
Phase 3 PEARL study evaluating durvalumab alone or chemotherapy in patients with advanced non-small cell lung cancer; results were posted in…
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL) [Phase 3]
A Phase 3 trial evaluating durvalumab alone or with chemotherapy for advanced non-small cell lung cancer (NSCLC) is active/not recruiting wi…
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib [Phase 2]
Phase 2 trial investigating atezolizumab and bevacizumab in EGFR-mutant non-small cell lung cancer after progression on osimertinib; study t…
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Stereotactic Ablative Radiotherapy With Nivolumab for Early-Stage Operable Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial investigating stereotactic ablative radiotherapy with nivolumab for early-stage operable non-small cell lung cancer (Stage I).
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Stereotactic Body Radiotherapy for the Treatment of OPD [Phase 2, Phase 3]
Clinical trial update of stereotactic body radiotherapy for non-small cell lung cancer in Phase 2/Phase 3.
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy [Phase 3]
Phase 3 trial evaluating atezolizumab plus cabozantinib versus docetaxel in metastatic non-small cell lung cancer previously treated with an…
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: BIO 300 Non-Small Cell Lung Cancer Study [Phase 1, Phase 2]
A completed Phase 1/Phase 2 trial update for BIO 300 in non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2023-12-19Clinical Trial Update: Her2-positive Lung Cancer Treated With Dedicated Drug [Phase 2]
A Phase 2 trial update for a HER2-positive non-small cell lung cancer treatment is reported as completed.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: A Study of RC48-ADC in Subjects With Advanced Non-small Cell Lung Cancer [Phase 1, Phase 2]
Phase 1/2 trial update for RC48-ADC in advanced non-small cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Survival Prolongation by Rationale Innovative Genomics [Phase 1, Phase 2]
Phase 1/2 trial update on survival outcomes for a regimen from Rationale Innovative Genomics in metastatic and stage IIIB non-small cell lun…
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy [Phase 2]
Phase 2 clinical trial update evaluating pevonedistat with carboplatin and paclitaxel in advanced non-small cell lung cancer patients previo…
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CLINICAL_TRIALS trial_result · 2023-12-14Clinical Trial Update: Study to Assess the Safety and Tolerability of Repeated Doses of an Investigational New Drug in Patients With Cancer and Cachexia. [Phase 1]
Phase 1 trial evaluating safety and tolerability of repeated doses of an investigational drug in cancer patients with cachexia; study comple…
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CLINICAL_TRIALS trial_result · 2023-12-13Clinical Trial Update: Evaluating the Efficacy of Atezolizumab in Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 2]
A Phase 2 trial evaluating the efficacy of atezolizumab in advanced non-small cell lung cancer has completed with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC [Phase 2]
Phase 2 trial update of neoadjuvant MPDL3280A (atezolizumab) with nab-paclitaxel and carboplatin in non-small cell lung cancer has completed…
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FDA approval · 2023-12-11FDA Approved: PEMETREXED — Original Application (Solco Healthcare US, LLC)
FDA approved the original generic application for pemetrexed (PEMETREXED) by Solco Healthcare US, LLC.
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Neoadjuvant PD-1 Antibody Plus Apatinib or Chemotherapy for Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial update evaluating neoadjuvant PD-1 antibody plus apatinib or chemotherapy for non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Trigriluzole With Nivolumab and Pembrolizumab in Treating Patients With Metastatic or Unresectable Solid Malignancies or Lymphoma [Phase 1]
Phase 1 trial assessing trigriluzole in combination with nivolumab and pembrolizumab for various metastatic or unresectable solid tumors and…
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CLINICAL_TRIALS trial_result · 2023-12-05Clinical Trial Update: CD40 Agonistic Antibody APX005M (Sotigalimab) in Combination With Nivolumab [Phase 1, Phase 2]
Phase 1/2 trial of CD40 agonist APX005M (sotigalimab) with nivolumab in cancer including metastatic non-small cell lung cancer and melanoma …
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CLINICAL_TRIALS trial_result · 2023-11-29Clinical Trial Update: Deciphering Afatinib Response and Resistance With INtratumour Heterogeneity [Phase 2]
Phase 2 trial update exploring afatinib response and resistance in intratumour heterogeneity for non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2023-11-27Clinical Trial Update: Sintilimab ± IBI305 Plus Chemotherapy (Pemetrexed + Cisplatin) for EGFRm + Locally Advanced or Metastasis Non-Squamous NSCLC Patients After EGFR-TKI Treatment Failure [Phase 3]
A Phase 3 trial evaluating sintilimab with IBI305 plus pemetrexed and cisplatin for EGFR-mutant, locally advanced or metastatic non-squamous…
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CLINICAL_TRIALS trial_result · 2023-11-27Clinical Trial Update: A Study of RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 Mutation [Phase 1, Phase 2]
A study investigating RC48-ADC in combination with Pyrotinib for locally advanced or metastatic non-small cell lung cancer with HER2 mutatio…