Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: OSE2101 Versus Chemotherapy in HLA-A2 Positive Patients With Advanced NSCLC After Immune Checkpoint Inhibitor Failure [Phase 3]
Phase 3 trial comparing OSE2101 to chemotherapy in HLA-A2 positive advanced NSCLC after immune checkpoint inhibitor failure was terminated; …
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CLINICAL_TRIALS research · 2024-02-01Clinical Trial Update: Neoadjuvant Immunotherapy Plus Chemotherapy for Potentially Resectable Stage IIIA/IIIB Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating neoadjuvant immunotherapy plus chemotherapy for potentially resectable stage IIIA/IIIB non-small cell lung cancer.
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FDA approval · 2024-01-31FDA Approved: TAGRISSO — Supplemental Application (AstraZeneca Pharmaceuticals LP)
FDA granted approval of a supplemental application for Tagrisso (osimertinib) submitted by AstraZeneca Pharmaceuticals LP.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A [Phase 3]
CANOPY-A is a Phase 3 trial evaluating canakinumab as adjuvant therapy for completely resected non-small cell lung cancer. The study was ter…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial results update for trastuzumab deruxtecan (Enhertu) in HER2-mutated metastatic non-small cell lung cancer; results have been p…
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Study to Evaluate Treatment Customized According to RAP80 and BRCA1 in Patients With Advanced Lung Carcinoma [Phase 3]
Phase 3 trial evaluating treatment tailored to RAP80 and BRCA1 in advanced non-small cell lung cancer with BRCA1 mutation; study terminated …
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO) [Phase 3]
Phase III clinical trial update for TY-9591 in locally advanced or metastatic non-small cell lung cancer (NCT05382728) is currently recruiti…
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: CHEckpoint Inhibition in Combination With an Immunoboost of External Beam Radiotherapy in Solid Tumors [Phase 2]
Phase 2 trial evaluating checkpoint inhibition in combination with external beam radiotherapy for solid tumors; study is completed.
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL [Phase 1, Phase 2]
Phase 1/2 trial update for CX-2029 in solid tumors and DLBCL completed; aims to identify safe and active dose levels.
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CLINICAL_TRIALS trial_result · 2024-01-18Clinical Trial Update: Osimertinib in Treating Participants With Stage I-IIIA EGFR-mutant Non-small Cell Lung Cancer Before Surgery [Phase 2]
Phase 2 trial evaluating osimertinib given before surgery in patients with stage I-IIIA EGFR-mutant non-small cell lung cancer. Results have…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789) [Phase 3]
A Phase 3 trial evaluating pemetrexed plus platinum chemotherapy with or without pembrolizumab in adults with tyrosine kinase inhibitor–resi…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Prospective Clinicogenomic Program [Phase 4]
A Phase 4 prospective clinicogenomic program in progress for non-small cell lung cancer and small-cell lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: M7824 With cCRT in Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Phase 2 trial update for M7824 in unresectable stage III non-small cell lung cancer has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: A Study of Avutometinib (VS-6766) + Defactinib in Recurrent KRAS G12V, Other KRAS and BRAF Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating avutometinib (VS-6766) in combination with defactinib in recurrent KRAS G12V, other KRAS and BRAF mutated non-small…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia [Phase 1]
Phase 1 study comparing repeated doses of an investigational drug versus placebo to assess effects on appetite in advanced cancer and anorex…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Biodistribution and Safety of the PET Probes [18F]FPRGD2 and [18F]FPPRGD2 [EARLY_Phase 1]
Phase 1 trial update assessing biodistribution and safety of PET probes [18F]FPRGD2 and [18F]FPPRGD2 in cancer patients; results posted afte…
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CLINICAL_TRIALS trial_result · 2024-01-11Clinical Trial Update: Trial of Consolidation Pembrolizumab After Concurrent Chemotherapy and Proton Reirradiation for Thoracic Recurrences of Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating consolidation pembrolizumab after concurrent chemotherapy and proton reirradiation for thoracic recurrences of non-…
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients [Phase 2]
Phase 2 clinical trial update evaluating targeted drugs guided by genomic profiles in metastatic non-small cell lung cancer (NSCLC).
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Efficacy and Biomarker Explanation of IBI-323 + Bevacizumab Plus Platinum Based Chemotherapy on ALK-Rearranged NSCLC [Phase 2]
Phase 2 clinical trial update on IBI-323 plus bevacizumab and platinum chemotherapy in ALK-rearranged non-small cell lung cancer, with effic…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: High Dose Vitamin A Compound in Treating Participants With Resectable Non-Small Cell Lung Cancer [EARLY_Phase 1]
Early-phase trial of a high-dose vitamin A compound in participants with resectable non-small cell lung cancer was terminated; results poste…
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: Serplulimab for Patients With Non-small Cell Lung Cancer (NSCLC) With TPS ≥ 50%: a Prospective, Single-center, Single-arm Phase 2 Study. [Phase 2]
A Phase 2 clinical trial evaluating serplulimab in NSCLC patients with high TPS (≥50%), conducted at a single center in Zhejiang, with outco…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Effect of Pembrolizumab With or Without Carboplatin and Paclitaxel on Immune Response in Patients With Recurrent or Stage IIIB-IV Non-small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating pembrolizumab with or without carboplatin and paclitaxel in recurrent or stage IIIB-IV non-small cell lung cancer h…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial PROCLAIM-CX-2009 evaluating safe and active doses of CX-2009 for selected solid tumors; trial status terminated with results…
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CLINICAL_TRIALS trial_result · 2023-12-29Clinical Trial Update: Neoadjuvant of Tislelizumab Combined With Chemotherapy Followed by Surgery in Unresectable Stage Ⅲ NSCLC [Phase 2]
Phase 2 trial update investigating neoadjuvanttislelizumab plus chemotherapy followed by surgery for unresectable stage III non-small cell l…
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CLINICAL_TRIALS trial_result · 2023-12-27Clinical Trial Update: A Study Exploring Efficacy of SIBP04 in Subjects With Non-squamous Non-small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating the efficacy of SIBP04 in subjects with non-squamous non-small cell lung cancer has completed.