Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Evaluating Modifiable Biomarkers for the Prediction of Immunotherapy Response and Toxicity
A completed clinical trial evaluating modifiable biomarkers to predict immunotherapy response and toxicity in non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: A Phase 1 Study of BPI-371153 in Subjects with Advanced Solid Tumors or Relapsed/Refractory Lymphoma [Phase 1]
Phase 1 trial of BPI-371153 in advanced solid tumors and lymphoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Olaparib (LYNPARZA) Plus Durvalumab (IMFINZI) in EGFR-Mutated Adenocarcinomas That Transform to Small Cell Lung Cancer (SCLC) and Other Neuroendocrine Tumors [Phase 2]
A Phase 2 trial evaluating Olaparib plus Durvalumab in EGFR-mutated non-small cell lung cancer that transformed to small cell lung cancer an…
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Cadonilimab in Patients (Pts) with Advanced Non-small Cell Lung Cancer (NSCLC) [Phase 2]
Cadonilimab is being studied in a Phase 2 trial for advanced non-small cell lung cancer and the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Survival Outcome of EGFR-TKI in Uncommon EGFR Mutant Advanced NSCLC
This clinical trial update addresses survival outcomes of EGFR-TKI therapy in patients with uncommon EGFR-mutant advanced non-small cell lun…
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Efficacy and Safety of IBI351 in Combination With Chemotherapy in Advanced Non-squamous Non-small Cell Lung Cancer Subjects With KRAS G12C Mutation [Phase 1]
This Phase 1 trial is evaluating the safety and preliminary efficacy of IBI351 in combination with chemotherapy for advanced non-squamous no…
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: A Study of AL8326 in Non-Small Cell Lung Cancer [Phase 1]
Clinical trial update for AL8326 in non-small cell lung cancer (Phase 1) shows the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer [NA]
This update reports the completion of a clinical trial evaluating health care coach support to reduce acute care use and costs in cancer pat…
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Switch Maintenance Pembrolizumab in Patients With NSCLC After First Line Platinum Doublet Chemotherapy [Phase 2]
Phase 2 trial evaluating switch maintenance pembrolizumab after first-line platinum doublet chemotherapy in metastatic non-small cell lung c…
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CLINICAL_TRIALS withdrawal · 2025-01-24Clinical Trial Update: Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers [Phase 1]
Phase 1 trial evaluating the combination of RMC-4630 and LY3214996 in metastatic KRAS-mutant cancers has been terminated. The study encompas…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: A Study of Atezolizumab (Tecentriq) to Investigate Long-term Safety and Efficacy in Previously-treated Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) [Phase 4]
Phase 4 study evaluating long-term safety and efficacy of atezolizumab (Tecentriq) in previously treated locally advanced or metastatic non-…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of HB0025 Injection in Patients With Advanced Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessing the safety and preliminary efficacy of HB0025 injection in patients with advanced solid tumors, includi…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors [Phase 1, Phase 2]
Phase 1/2 study of CBX-12 in adults with advanced or metastatic refractory solid tumors. The trial includes multiple cancer types and is cur…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Studying An Investigational Drug Crizotinib (PF-02341066) In Non Non-Small Cell Lung Cancer Tumors That Are Positive For Anaplastic Lymphoma Kinase (ALK) [Phase 1]
Phase 1 trial evaluating Pfizer's investigational crizotinib (PF-02341066) in ALK-positive non-small cell lung cancer was terminated, with r…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Nintedanib Plus EGFR TKI In EGFR-mutated Non-small Cell Lung Cancer Patients [Phase 1, Phase 2]
The document announces an ongoing Phase 1/2 trial evaluating the combination of nintedanib with an EGFR tyrosine kinase inhibitor in patient…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: AI-HOPE Lung Cancer: Building a Predictive Tool for Metastatic Lung Cancer
This document provides an update on the AI-HOPE Lung Cancer trial, which aims to build a predictive tool for metastatic non-small cell lung …
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: F-18 FDG PET/CT and CT in Initial Staging of Non-small Lung Cancer
This clinical trial evaluates F-18 FDG PET/CT plus CT for initial staging of non-small cell lung cancer, and the study status is not yet rec…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Keynatinib in Treated Patients With NSCLC and Brain Metastases [Phase 2]
Phase 2 trial of Keynatinib in previously treated non-small cell lung cancer with brain metastases has completed; the update does not detail…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation [Phase 3]
Phase 3 trial update comparing adagrasib (MRTX849) to docetaxel in KRAS G12C-mutant non-small cell lung cancer; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: A Study of SEA-CD40 Given With Other Drugs in Cancers [Phase 2]
Phase 2 study of SEA-CD40 in combination with other therapies for melanoma and non-small cell lung cancer has completed and results were pos…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating NC-6004 (a cisplatin nanoparticle formulation) in combination with gemcitabine has completed testing i…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation [Phase 3]
Phase 3 study of adagrasib (MRTX849) versus docetaxel in advanced/metastatic KRAS G12C non-small cell lung cancer is active/not recruiting w…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Real-world Study of Sunvozertinib Treatment in Advanced EGFR-Mutant NSCLC After EGFR-TKI Treatment Failure
A real-world study is planned to evaluate sunvozertinib in patients with advanced EGFR-mutant non-small cell lung cancer after failure of pr…
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Standard Care With or Without Early Palliative Care Provided by Palliative Care Specialist in Advanced Non-small Cell Lung Cancer Patients [NA]
This clinical trial investigates whether adding early palliative care by a palliative care specialist to standard care improves outcomes in …
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CLINICAL_TRIALS research · 2025-01-21Clinical Trial Update: Efficacy and Safety of Ensartinib in Neoadjuvant Therapy for Stage IIA - IIIB (Operable or Potentially Operable) ALK-Positive Lung Adenocarcinoma ：A Multicenter, Real-World Clinical Study [Phase 4]
Phase 4 multicenter real-world study evaluating the efficacy and safety of ensartinib as neoadjuvant therapy for stage IIA-IIIB ALK-positive…