Non-small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Molecular Analysis of Thoracic Malignancies
This clinical trial update describes ongoing molecular analyses of thoracic malignancies, including thymic tumors and thoracic carcinomas, w…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Furmonertinib Combined With Intrathecal Chemotherapy and Stereotactic Radiotherapy (SRT) for EGFR-Mutated NSCLC Patients With Brain Parenchymal and Leptomeningeal Metastases [Phase 2]
A Phase 2 clinical trial is assessing furmonertinib in combination with intrathecal chemotherapy and stereotactic radiotherapy for EGFR-muta…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform
An observational lung cancer trial is recruiting to collect tissue samples to train and validate a live tumor diagnostic platform. The study…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of Usage of Brigatinib in the Treatment of Adult Participants for Approved Indications In South Korea
Ongoing recruitment in South Korea for brigatinib to treat adults with approved indications in non-small cell lung cancer.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Study of Oral EGFR Inhibitor DZD6008 Combined With Sunvozertinib in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN8) [Phase 1, Phase 2]
Phase 1/2 clinical trial NCT07079475 is testing DZD6008 in combination with Sunvozertinib for advanced EGFR-mutant non-small cell lung cance…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46) [Phase 3]
This is a Phase 3 clinical trial update comparing pembrolizumab monotherapy to sacituzumab govitecan in combination with pembrolizumab for m…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: The Selective Personalized Radio-Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer Trial 2 [Phase 2]
Notes a Phase 2 trial (Trial 2) of selective personalized radio-immunotherapy for locally advanced non-small cell lung cancer, currently not…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Evaluation of Lymph Node Analysis Using One Step Nucleic Acid Amplification (OSNA) in Patients With Lung Cancer Who Underwent Robotic Lung Resection, Comparison With Traditional Methods
This clinical trial assesses the use of One Step Nucleic Acid Amplification (OSNA) for lymph node analysis in non-small cell lung cancer pat…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Sunvozertinib Treatment in Untreated Advanced NSCLC With EGFR Uncommon Mutations [Phase 2]
Phase 2 study of Sunvozertinib in untreated advanced non-small cell lung cancer with uncommon EGFR mutations; currently recruiting.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors [Phase 1]
A Phase 1 study evaluating KIN-2787 in participants with BRAF and/or NRAS mutation-positive solid tumors. The study includes patients with n…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC
Clinical trial update showing ongoing recruitment for a study evaluating whether fat-free mass-based carboplatin dosing affects chemotherapy…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes [Phase 1, Phase 2]
Phase I/II clinical trial of HYP-6589 as monotherapy and in combination with tyrosine kinase inhibitors for advanced non-small cell lung can…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer [Phase 1]
The update covers a Phase 1 study of TILT-123, an oncolytic adenovirus, in combination with pembrolizumab for refractory non-small cell lung…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating infliximab or vedolizumab to treat immune checkpoint inhibitor-related colitis in patients with genito…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors [Phase 1]
A Phase 1 study evaluating PT0511 in adults with KRAS-mutated or amplified advanced solid tumors, including colorectal cancer, pancreatic ca…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating lorlatinib in patients with ROS1-positive advanced or metastatic non-small cell lung cancer. The study is …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer [Phase 1, Phase 2]
A phase 1/phase 2 clinical trial evaluating SHR-A2102 in combination with Adebrelimab (with or without other antitumor therapy) for advanced…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects
This clinical trial update describes a study investigating new biomarkers of exposure and effects from air pollution on tumors and respirato…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Garsorasib In KRAS G12C Mutant Locally Advanced and Metastatic NSCLC [Phase 2]
Phase 2 trial of Garsorasib in KRAS G12C-mutant locally advanced or metastatic non-small cell lung cancer; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Crizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial) [Phase 3]
This is a Phase 3 clinical trial update for crizotinib in ALK-positive stage IB-IIIA non-small cell lung cancer as part of the ALCHEMIST pro…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene. [Phase 2]
A Phase 2 clinical trial is evaluating zanidatamab for solid tumors with HER2 gene alterations across multiple indications and is currently …
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Platform Study of Novel Agents in Combination With Radiotherapy in NSCLC [Phase 1]
A Phase 1 platform trial evaluating novel agents in combination with radiotherapy for non-small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Epidemiology of Young Lung Cancer - Survey
A clinical trial survey investigating the epidemiology of young non-small cell lung cancer, sponsored by Addario Lung Cancer Medical Institu…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Using ctDNA to Determine Therapies for Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating whether circulating tumor DNA (ctDNA) can guide therapy choices for non-small cell lung cancer. The stud…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: A Phase II Study of SSGJ-706 Monotherapy and Combination Therapy in Advanced Non-Small Cell Lung Cancer（NSCLC） Patients [Phase 2]
This clinical trial update reports on a Phase II study evaluating SSGJ-706 as monotherapy and in combination for first-line advanced non-sma…