Catalyst Wire Dossier Catalyst Wire Dossier
CLINICAL_TRIALS research · 2025-12-24

Clinical Trial Update: Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46) [Phase 3]

View source ↗

Summary

This is a Phase 3 clinical trial update comparing pembrolizumab monotherapy to sacituzumab govitecan in combination with pembrolizumab for metastatic non-small …

Upgrade for the full analysis, importance score, and drug timeline.

Diseases / indications

Drugs mentioned

  • KEYTRUDA (PEMBROLIZUMAB)
  • TRODELVY (sacituzumab govitecan)

Snippet

Sponsor: Merck Sharp & Dohme LLC | Conditions: Carcinoma, Non-Small-Cell Lung | Phase 3 | Status: ACTIVE_NOT_RECRUITING