Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder [EARLY_Phase 1]
This clinical trial update reports completion of a Phase 1 study evaluating ketamine in combination with motivational enhancement therapy fo…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Evaluating the Efficacy of a Text Messaging-based Shisha Smoking Cessation Intervention [NA]
A clinical trial from The University of Hong Kong is evaluating whether a text messaging-based intervention can help people quit shisha toba…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency [NA]
This clinical trial update reports the completion of a study evaluating how nicotine flux and nicotine form affect subjective effects relate…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH [NA]
A completed clinical trial evaluated how the pH of e-cigarette liquids influences short-term cardiovascular effects.
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments [NA]
The INITIATE study is currently recruiting to evaluate initiating nicotine dependence treatment for smokers admitted to emergency department…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: AAT + tDCS to Reduce Cue-induced Craving and Smoking Behavior [NA]
A completed clinical trial evaluated the combination of AAT and transcranial direct current stimulation (tDCS) to reduce cue-induced craving…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Adaptation and Evaluation of a Culturally and Gender Relevant Tobacco Cessation Among Women in Brazil: An Integrated mHealth Approach [NA]
A clinical trial in Brazil is evaluating a culturally and gender-tailored, integrated mHealth tobacco cessation program for women and is cur…
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Dyadic Financial Incentive Treatments for Dual Smoker Couples [NA]
University of Georgia is recruiting for a study on dyadic financial incentive treatments for dual smoker couples to promote smoking cessatio…
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CLINICAL_TRIALS research · 2025-07-07Clinical Trial Update: E-cigarette Cessation in Adults Who Co-use Cannabis [Phase 4]
This is an ongoing Phase 4 trial evaluating strategies to stop e-cigarette use in adults who also use cannabis; recruitment is currently und…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Cognitive and Affective Mechanisms Underlying an Olfactory Approach to Modify Cigarette Craving [NA]
A University of Pittsburgh-sponsored study is examining cognitive and affective mechanisms underlying an olfactory approach to modify cigare…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Integrating Financial Coaching and Smoking Cessation Coaching [Phase 3]
A Phase 3 clinical trial from NYU Langone Health is evaluating an integrated financial coaching and smoking cessation coaching program to ai…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Evaluation of the Effectiveness of a Very Brief Smoking Cessation Intervention in Family Health Centers [NA]
This completed clinical trial evaluated the effectiveness of a very brief smoking cessation intervention delivered in family health centers.
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Study Assessing Efficacy and Safety of NFL-101 as a Tobacco Cessation Therapy [Phase 2]
A Phase 2 trial evaluating the efficacy and safety of NFL-101 for nicotine dependence has completed.
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking Cessation [EARLY_Phase 1]
Early Phase 1 trial evaluating whether isradipine enhances virtual reality cue-exposure therapy for smoking cessation; results have been pos…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Young Adult Tobacco/Nicotine and Cannabis Co-use [NA]
A Medical University of South Carolina-sponsored clinical trial on young adult tobacco/nicotine use and cannabis co-use is currently recruit…
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Efficacy of Centanafadine SR as a Potential Smoking Cessation Treatment [Phase 2]
Phase 2 trial evaluating Centanafadine SR for smoking cessation; results have been posted.
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Evaluation of the Added Value of Sophrology on the Intensity of Craving During Smoking Withdrawal [NA]
A terminated clinical trial evaluating whether sophrology adds value in reducing craving during smoking withdrawal.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Testing the mHealth App Intervention for Nondaily Smokers "SiS4" [NA]
A Massachusetts General Hospital-backed clinical trial is evaluating an mHealth app called SiS4 to aid nondaily smokers in smoking cessation…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults [NA]
A completed clinical trial evaluated a smartphone application (ACT on Vaping) to aid vaping cessation in young adults; results have been pos…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients [NA]
An ongoing clinical trial is evaluating whether stimulation with a GLP-1 receptor agonist affects smoking consumption in adults with Type 2 …
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FDA approval · 2025-05-23FDA Approved: BUPROPION HYDROCHLORIDE XL — Supplemental Application (Slate Run Pharmaceuticals, LLC)
The FDA approved a supplemental application for Bupropion hydrochloride XL from Slate Run Pharmaceuticals, approving the extended-release fo…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Quit Smoking Study for People Who Use E-Cigarettes [Phase 2]
Phase 2 quit-smoking study for people who use e-cigarettes has completed the trial and posted results on May 22, 2025.
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Combination of Acupuncture, Auricular Acupressure and Nicotine Replacement Therapy for Smoking Cessation [NA]
A clinical trial from The University of Hong Kong is evaluating a combination of acupuncture, auricular acupressure, and nicotine replacemen…
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: The Moment Study: Mixed Method E-cigarette Study [NA]
The Moment Study: Mixed Method E-cigarette Study has completed and posted results for its investigation of e-cigarette use and smoking behav…
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FDA approval · 2025-05-02FDA Approved: VARENICLINE — Original Application (Aurobindo Pharma Limited)
The FDA approved a generic version of varenicline from Aurobindo Pharma Limited via an Original Application (ANDA) for smoking cessation.