Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Designing a Smoking Intervention for Youth Smokers Using Q-Methodology: A Pilot Randomized Controlled Trial [NA]
This is a protocol for a pilot randomized controlled trial that uses Q-methodology to design a smoking intervention for youth smokers, with …
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia [Phase 1]
Phase 1 trial evaluating injectable naltrexone in combination with oral bupropion for smoking cessation in adults with schizophrenia has bee…
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EMA approval · 2025-09-11EMA Authorised: Champix (varenicline) — Pfizer Europe MA EEIG
The EMA authorised Champix (varenicline) for tobacco use cessation in the European Union, with Pfizer Europe MA EEIG as the marketing author…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers [Phase 1]
A Phase 1 study in smokers assessed the acute pharmacokinetic and pharmacodynamic effects of tobacco-free oral nicotine pouches, focusing on…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: CoQuit Study for Smoking Cessation [NA]
The CoQuit study for smoking cessation has completed and its results have been posted.
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: EFFECT OF WIM HOF BREATHING EXERCISE ON VENTILATORY FUNCTIONS IN SMOKERS [NA]
This clinical trial explores whether Wim Hof breathing exercises affect ventilatory function in people who smoke or vape and have moderate t…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: IV Pulsed-Nicotine as a Model of Smoking: The Effects of Dose and Delivery Rate [EARLY_Phase 1]
An early-phase study evaluating how dose and delivery rate of intravenously pulsed nicotine influence its use as a model of smoking in nicot…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Effects of Cannabidiol on Stress and Nicotine Withdrawal [Phase 1]
A Phase 1 trial at Johns Hopkins is evaluating cannabidiol for stress and nicotine withdrawal and is currently recruiting. The study relates…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: The Effects of Electronic Cigarette and Traditional Cigarette
This completed clinical trial from Atılım University assessed the effects of electronic cigarettes and traditional cigarettes on nicotine de…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Semaglutide for Smoking Cessation in Patients With Diabetes [Phase 3]
A Phase 3 trial is evaluating semaglutide for smoking cessation in adults with type 2 diabetes; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Nicotine Pharmacokinetics and Pharmacodynamics of Two Variants of VM 1.0 Compared to Cigarettes in Adult Current Smokers [NA]
A clinical trial update from Philip Morris evaluating the pharmacokinetics and pharmacodynamics of two VM 1.0 nicotine variants compared wit…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups [NA]
The trial update reports the completion of SmokefreeSGM, a feasibility text-based smoking cessation study for sexual and gender minority gro…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Overcoming Nicotine Dependence to Enable Quitting [Phase 1, Phase 2]
Rush University Medical Center is conducting Phase 1/2 clinical trials to test approaches for overcoming nicotine dependence to help people …
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: GeoScan and Remote Geo Smoking Study: Neural and Behavioral Correlates of Smokers' Exposure to Retail Environments [NA]
Completed results from a study examining neural and behavioral responses of smokers to exposure in retail environments, sponsored by the Abr…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Family and Peer Influences on Nicotine Dependence in Medical Students of South Punjab
A completed clinical trial from Nishtar Medical University examining how family functioning and peer influence relate to nicotine dependence…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: tDCS Plus Varenicline for Smoking Cessation [Phase 4]
A Phase 4 trial is evaluating the combination of transcranial direct current stimulation (tDCS) and varenicline for smoking cessation, with …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal [NA]
A ClinicalTrials.gov entry from the University of Alabama at Birmingham describes a study exploring racial differences in circadian and slee…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Quit Smoking Text Message Study [NA]
A Yale University trial completed evaluating a text-message-based intervention to support smoking cessation. The study investigated whether …
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness [Phase 4]
Phase 4 trial update showing PARQuit, a smoking cessation intervention, has completed in adults with serious mental illness.
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CLINICAL_TRIALS trial_result · 2025-07-31Clinical Trial Update: Smartphone Based Smoking Cessation Intervention [Phase 2, Phase 3]
Clinical trial update indicating completion of Phase 2 and Phase 3 testing for a smartphone-based smoking cessation intervention, with resul…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Human Perception of Odors and Odor Blockers [NA]
Completed clinical trial evaluating human perception of odors and odor blockers in relation to tobacco smoking behaviors.
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CLINICAL_TRIALS research · 2025-07-25Clinical Trial Update: Switch or Quit R01 [NA]
A clinical trial update shows the study 'Switch or Quit R01' sponsored by the Medical University of South Carolina is currently recruiting a…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Cessation Screening Project [Phase 4]
Phase 4 clinical trial update on cessation screening for nicotine dependence has completed. Sponsor: University of Wisconsin, Madison.
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CLINICAL_TRIALS research · 2025-07-23Clinical Trial Update: Mindful Breaths: Mindfulness for Young Adult Vaping [NA]
A Tulane University-sponsored clinical trial entry for Mindful Breaths: Mindfulness for Young Adult Vaping, studying vaping cessation; the s…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: Effects of Semaglutide on Nicotine Intake [Phase 2]
Phase 2 trial evaluating semaglutide for reducing nicotine intake in adults with tobacco use disorder; the study has completed and results w…