Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers [NA]
A randomized trial evaluating whether availability of e-cigarette flavors influences abstinence in smokers has been terminated.
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Cigarette Packaging of Low Nicotine Cigarettes [NA]
This completed clinical trial evaluated the packaging of low-nicotine cigarettes in smokers; sponsor was the Abramson Cancer Center at Penn …
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Improving Smoking Abstinence Outcomes in the African American Community Through Extended Treatment [Phase 3]
A Phase 3 clinical trial is evaluating extended treatment to improve smoking abstinence outcomes in the African American community.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: the Effectiveness of AI Molar Mind for Smoking Cessation Through Dental Health Evaluation [NA]
A clinical trial is evaluating the AI-based tool Molar Mind for promoting smoking cessation by assessing dental health, and the study is cur…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: AI-Enhanced App-based Intervention for Adolescent E-cigarette Cessation [NA]
A clinical trial protocol for an AI-enhanced app to help adolescents cease e-cigarette use; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation [Phase 2]
Phase 2 clinical trial evaluating varenicline with nicotine lozenges and a smartphone adherence intervention for smoking cessation, currentl…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Impact of Lifestyle on Health Maintenance: A Randomized Controlled Trial [NA]
A ClinicalTrials.gov entry from the University of Zadar describes a randomized controlled trial assessing how lifestyle factors influence he…
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases [NA]
This completed clinical trial from Virginia Tech examined factors that promote or mitigate illegal tobacco purchases related to cigarettes a…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Sex Differences in E-Cigarette Perception [NA]
This Yale University-backed clinical trial investigates sex differences in perceptions of e-cigarettes among individuals with nicotine depen…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: rTMS in Promoting Smoking Cessation and Preventing Relapse in Current Smokers [NA]
This clinical trial update notes an ongoing rTMS study at Roswell Park Cancer Institute aimed at promoting smoking cessation and preventing …
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV [NA]
A completed clinical trial reports on the effectiveness of an integrated treatment targeting smoking cessation and anxiety/depression in peo…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Reward Sensitivity and Pharmacotherapy for Smoking Cessation [Phase 4]
Phase 4 study at MD Anderson evaluating reward sensitivity and pharmacotherapy for smoking cessation; currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: App for Reducing Cravings to Smoke [Phase 2]
Phase 2 clinical trial update shows ongoing recruitment for an app designed to reduce cravings to smoke, sponsored by H. Lee Moffitt Cancer …
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders [Phase 3]
Phase 3 clinical trial update on adaptive nicotine substitution to maintain smoking reduction or abstinence in nicotine responders; the Rose…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Cessation in Adults Using Nicotine-Containing E Cigarettes [Phase 3]
Phase 3 trial evaluating the efficacy and safety of cytisinicline for vaping cessation in adults using nicotine-containing e-cigarettes; stu…
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FDA approval · 2026-02-05FDA Approved: NICOTINE — Supplemental Application (McKesson Corporation dba SKY Packaging)
FDA approved a supplemental application for NICOTINE (nicotine polacrilex) submitted by McKesson Corporation dba SKY Packaging.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: An Interactive Smartphone Application to Motivate Smokers to Quit [NA]
A clinical trial update for an interactive smartphone app aimed at motivating smokers to quit, sponsored by Ottawa Heart Institute Research …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Vaping Cessation Using the Ottawa Model for Smoking Cessation Among E-Cigarette Users [NA]
An active-not-recruiting trial at the Ottawa Heart Institute is evaluating the Ottawa Model for smoking cessation to help e-cigarette users …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Effects of Relighting on Smoke Toxicant Deliveries and Subjective Smoking Measures [NA]
This clinical trial from the University of Minnesota investigates whether relighting a cigarette alters smoke toxicant delivery and subjecti…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine Addiction [Phase 1]
A Phase 1 clinical trial examining nicotinic hepatic metabolism and its effect on neuroreceptor substrates related to nicotine addiction; th…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Tobacco Cessation at FDNY [Phase 4]
A Phase 4 trial evaluating a tobacco cessation intervention for FDNY personnel has completed.
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation [NA]
Completed clinical trial from University of Nebraska evaluating incentive-based and media literacy approaches to improve vaping cessation, w…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Kick-Nic! Youth Quit Vaping App [Phase 2]
A Phase 2 clinical trial at Yale University evaluating Kick-Nic!, a youth vaping cessation app aimed at reducing nicotine use; the study is …
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence [Phase 2]
Phase 2 trial evaluating whether kava can aid tobacco cessation and alleviate stress and insomnia during abstinence; recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: Lemongrass (Cymbopogon Citratus) on Nicotine Dependence, Cotinine Levels, and Related Biomarkers in Adult Smokers [NA]
A completed clinical trial evaluated lemongrass effects on nicotine dependence, cotinine levels, and related biomarkers in adult smokers.