Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity
This completed clinical trial investigates multimodal neuroimaging and genetic biomarkers to assess nicotine addiction severity.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Implementation of Transcranial Magnetic Stimulation for Smoking Cessation [Phase 4]
Phase 4 clinical trial update indicating recruitment for a study evaluating transcranial magnetic stimulation as an aid to smoking cessation…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC) [NA]
Completed clinical trial evaluating the pharmacokinetics and pharmacodynamics of nicotine delivered via a standardized research electronic c…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community [NA]
An update on an ongoing trial examining metabolome and gut microbiome changes during smoking cessation in people on long-term drug therapy i…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum [NA]
Feasibility and acceptability trial to reduce tobacco and cannabis use during pregnancy and postpartum, sponsored by the University of Pitts…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Exenatide for Smoking Cessation and Prevention of Weight Gain [Phase 2]
Phase 2 trial update shows completion of a study evaluating exenatide for smoking cessation and prevention of weight gain.
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: A Study Of Vagal Nerve Stimulation In Conjunction With NRT For Smoking Cessation [Phase 2, Phase 3]
Mayo Clinic sponsors a clinical trial evaluating vagal nerve stimulation with nicotine replacement therapy for smoking cessation, in Phase 2…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers
A UCLA-led clinical trial evaluating brain glutamate differences between male and female cigarette smokers has completed, with results poste…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Smoking Cessation and Menstrual Cycle Phase [Phase 4]
Phase 4 clinical trial investigating how the menstrual cycle phase may influence smoking cessation outcomes; currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-19Clinical Trial Update: Smoking Harm Reduction Using E-cigarettes and Cytisine [NA]
ClinicalTrials.gov update for a study evaluating smoking harm reduction using e-cigarettes and cytisine; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Effects of E-cigs vs Pouches on Cigarette Smoking and Addiction [NA]
This clinical trial update indicates that Yale University is recruiting for a study evaluating the effects of electronic cigarettes vs nicot…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: The Use of tDCS for Vaping Reduction [NA]
This clinical trial is recruiting to evaluate whether transcranial direct current stimulation (tDCS) can reduce vaping and nicotine dependen…
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CLINICAL_TRIALS withdrawal · 2026-03-18Clinical Trial Update: Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers [NA]
This clinical trial update notes that the study on how cigarette direct mail marketing influences smoking behaviors among high- and low-soci…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Effects of Nicotine Dependence on Multidimensional Health Outcomes [NA]
A clinical trial entry from Izmir Democracy University studying how nicotine dependence affects various health outcomes in tobacco use disor…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers [NA]
Clinical trial evaluating noncombustible nicotine delivery systems as potential harm reduction tools for persistent cigarette smokers. Spons…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Enhancing Smoking Cessation for African American People Everywhere [Phase 2]
This is a Phase 2 clinical trial evaluating ESCAPE Intervention+NRT and quitSTART Intervention+NRT (with nicotine replacement therapy) for s…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Addictive Potential of LCCs in Dual Users [NA]
A completed clinical trial (NCT03496077) evaluated the addictive potential of LCCs in dual users with tobacco use disorder; results have bee…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents [NA]
A Yale University trial describes a virtual reality intervention to prevent e-cigarette use and nicotine dependence in adolescents, focusing…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Vaping and Smoking Withdrawal Project [NA]
A clinical trial update announcing recruitment for the Vaping and Smoking Withdrawal Project, a SUNY Buffalo study comparing acute abstinenc…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Combination Nicotine Replacement Therapy, Cytisine, or Varenicline for Smoking Cessation [Phase 4]
Phase 4 clinical trial evaluating combinations of nicotine replacement therapy, cytisine, or varenicline for smoking cessation is currently …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes [NA]
A clinical trial, sponsored by the Medical University of South Carolina, investigates the impact of menthol cigarette and e-cigarette regula…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Enhancing Smoking Cessation Via Telehealth Options in Primary Care [NA]
A clinical trial is recruiting to test telehealth-enabled smoking cessation support in primary care settings.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Smart Olfaction App to Reduce Relapse [EARLY_Phase 1]
A study to evaluate a Smart Olfaction App to reduce relapse in nicotine dependence, in early-phase development and not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Effects of Smoking on Network Connectivity in Patients With Schizophrenia Symptoms in Scz Patients [NA]
A clinical trial from The Hong Kong Polytechnic University is studying how smoking affects brain network connectivity in individuals with sc…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study [NA]
This open-label, pilot trial examined whether mindfulness training changes hippocampal network connectivity in tobacco vaping adolescents; t…