Nicotine Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-09-30Clinical Trial Update: Choices-Teen: A Bundled Risk Reduction Intervention for Juvenile Justice Females [NA]
This is a completed trial update for Choices-Teen, a bundled risk-reduction intervention aimed at juvenile justice females to address alcoho…
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FDA label_change · 2014-09-19FDA Approved: CHANTIX — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA supplemental application for CHANTIX (varenicline tartrate) submitted by Pfizer to modify the labeling.
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CLINICAL_TRIALS trial_result · 2014-09-19Clinical Trial Update: Memory Reconsolidation Blockade as a Novel Intervention for Nicotine Dependence [Phase 3]
Phase 3 trial evaluating memory reconsolidation blockade as a novel intervention for nicotine dependence (smoking cessation). The study is c…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: Proof-Of-Concept Investigation With a Neurosteroid Analog (Ganaxolone) as a Smoking Cessation Candidate [Phase 2]
Phase 2 proof-of-concept study evaluating ganaxolone as a candidate for smoking cessation; study completed with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-08-20Clinical Trial Update: Smoking-Cessation and Stimulant Treatment (S-CAST) [Phase 3]
Phase 3 clinical trial update for S-CAST evaluating smoking-cessation and stimulant treatment in cocaine and methamphetamine dependence.
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CLINICAL_TRIALS trial_result · 2014-08-15Clinical Trial Update: 'Questions About Quitting' Smoking Cessation Trial [NA]
This completed smoking cessation trial has posted results as of 2014; the update does not indicate a new drug approval.
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CLINICAL_TRIALS research · 2014-08-06Clinical Trial Update: P60 Program Project Grant-Outreach for Smoke-Free Homes [NA]
This clinical trial entry notes that the P60 Program Project Grant-Outreach for Smoke-Free Homes study sponsored by the University of Minnes…
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CLINICAL_TRIALS trial_result · 2014-08-01Clinical Trial Update: Concurrent Bupropion / Varenicline for Smoking Cessation [Phase 3]
Phase 3 trial evaluating the combination of bupropion and varenicline for smoking cessation has completed, with results posted.
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FDA approval · 2014-07-28FDA Approved: CHANTIX — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
The FDA approved a supplemental application for CHANTIX (varenicline tartrate) submitted by Pfizer Laboratories Div Pfizer Inc, indicating a…
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CLINICAL_TRIALS trial_result · 2014-07-03Clinical Trial Update: Varenicline and Smoking Cessation in Schizophrenia [Phase 2]
Phase 2 trial evaluating varenicline for smoking cessation in individuals with schizophrenia. Results were posted in 2014.
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CLINICAL_TRIALS research · 2014-07-01Clinical Trial Update: TNS for Treating Nicotine Craving [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating transcutaneous nerve stimulation (TNS) for nicotine craving is being conducted by Santa Casa Medical S…
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Promoting Smoking Cessation in the Community Via Quit to Win Contest 2013 [NA]
The University of Hong Kong completed a community-based trial aimed at promoting smoking cessation through a Quit to Win contest. The study …
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Pilot Study on Mindfulness for Tobacco and Alcohol in University Students [EARLY_Phase 1]
This pilot early-phase 1 trial evaluated mindfulness-based strategies for reducing nicotine dependence and alcohol use in university student…
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CLINICAL_TRIALS trial_result · 2014-06-16Clinical Trial Update: Efficacy and Safety Study of Nicotine Mint Lozenge (2mg and 4mg) in Smoking Cessation [Phase 3]
Phase 3 results from a study of nicotine mint lozenges (2 mg and 4 mg) evaluating efficacy and safety in aiding smoking cessation.
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FDA approval · 2014-06-11FDA Approved: NICORETTE ORIGINAL — Supplemental Application (Haleon US Holdings LLC)
The FDA approved a supplemental application for NICORETTE ORIGINAL (nicotine polacrilex) from Haleon US Holdings LLC, authorizing continued …
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FDA approval · 2014-06-11FDA Approved: NICORETTE 4MG FRUIT CHILL GUM, LIL DRUG STORE — Supplemental Application (Lil' Drug Store Products, Inc.)
The FDA approved a supplemental application for Lil' Drug Store Products to market NICORETTE 4MG FRUIT CHILL GUM (nicotine polacrilex) as a …
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CLINICAL_TRIALS trial_result · 2014-06-09Clinical Trial Update: A Multi-National Study To Assess How Effective And Safe The Smoking Cessation Medicine Varenicline Is In Smokers Who Have Already Tried Varenicline In The Past As A Prescription Medicine From Their Usual Healthcare Provider [Phase 4]
A Phase 4 multinational study evaluated the effectiveness and safety of varenicline in smokers who had previously used varenicline; results …
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CLINICAL_TRIALS research · 2014-06-04Clinical Trial Update: Exploring Occupancy of Dopamine D3 Receptor by Buspirone in Humans Using PET [Phase 1, Phase 2]
A Phase 1/2 clinical trial using PET to study occupancy of dopamine D3 receptors by buspirone in humans, in the context of smoking cessation…
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CLINICAL_TRIALS withdrawal · 2014-05-23Clinical Trial Update: Concurrent PET D2/D3 Receptor Imaging and fMRI Smoking Cue Reactivity in Smokers [Phase 1]
A Phase 1 study using concurrent D2/D3 receptor PET imaging and fMRI during smoking cue exposure in nicotine-dependent individuals has been …
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FDA approval · 2014-04-17FDA Approved: NICORETTE ORIGINAL — Supplemental Application (Haleon US Holdings LLC)
FDA approves a supplemental application for NICORETTE ORIGINAL (nicotine polacrilex) from Haleon US Holdings LLC.
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FDA approval · 2014-04-17FDA Approved: NICORETTE 4MG FRUIT CHILL GUM, LIL DRUG STORE — Supplemental Application (Lil' Drug Store Products, Inc.)
FDA approved a supplemental application for NICORETTE 4MG FRUIT CHILL GUM from Lil' Drug Store Products, Inc., adding this product to its ap…
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CLINICAL_TRIALS trial_result · 2014-04-16Clinical Trial Update: Improving Smoking Cessation Quitlines: Pilot Study of Acceptance Therapy [NA]
This completed pilot trial tested acceptance commitment therapy aimed at improving the effectiveness of smoking-cessation quitlines; results…
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CLINICAL_TRIALS trial_result · 2014-04-15Clinical Trial Update: Auriculotherapy for Smoking Cessation: Pilot [NA]
This clinical trial update reports the completed pilot study of auriculotherapy (ear acupuncture) for smoking cessation, with results posted…
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CLINICAL_TRIALS trial_result · 2014-04-14Clinical Trial Update: Health Effects of SLT, Cigarette Smoking, and New Tobacco Products [Phase 2]
Phase 2 clinical trial assessing health effects of smokeless tobacco, cigarette smoking, and new tobacco products in nicotine dependence.
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CLINICAL_TRIALS research · 2014-03-31Clinical Trial Update: TRIAD Project: Qualitative Study of Adolescent Depression and Smoking
A completed qualitative trial update from the TRIAD Project exploring how adolescent depression relates to smoking behavior.